STRINGSTRING
BCL9 BCL9 LRP1B LRP1B FZD8 FZD8 ROR2 ROR2 RYK RYK LRP8 LRP8 FZD4 FZD4 H2ZXM4_LATCH H2ZXM4_LATCH TCF7L1 TCF7L1 H2ZYH3_LATCH H2ZYH3_LATCH LOC102346005 LOC102346005 H3A4P0_LATCH H3A4P0_LATCH UCKL1 UCKL1 H3A5Z1_LATCH H3A5Z1_LATCH WLS WLS LOC102358266 LOC102358266 LEF1 LEF1 APC APC H3A8H2_LATCH H3A8H2_LATCH WNT7A WNT7A WNT9B WNT9B DKK2 DKK2 WNT5A WNT5A WNT11 WNT11 H3ABE1_LATCH H3ABE1_LATCH H3ABR4_LATCH H3ABR4_LATCH LOC102353948 LOC102353948 LOC102350744 LOC102350744 CTNNBIP1 CTNNBIP1 SFRP2 SFRP2 GSK3A GSK3A H3ADZ3_LATCH H3ADZ3_LATCH BAMBI BAMBI H3AF20_LATCH H3AF20_LATCH WNT16 WNT16 PORCN PORCN WNT3 WNT3 APC2 APC2 CSNK1A1 CSNK1A1 SFRP1 SFRP1 ROR1 ROR1 LRP3 LRP3 PCSK9 PCSK9 PYGO2 PYGO2 SFRP1-2 SFRP1-2 H3AP48_LATCH H3AP48_LATCH SOST SOST LOC102348686 LOC102348686 WIF1 WIF1 DKK3 DKK3 GSK3B GSK3B FZD3 FZD3 NDP NDP AXIN1 AXIN1 LDLRAP1 LDLRAP1 CTBP2 CTBP2 H3AXS1_LATCH H3AXS1_LATCH TSPAN12 TSPAN12 FZD1 FZD1 LOC102359071 LOC102359071 DAB1 DAB1 CTBP1 CTBP1 SFRP5 SFRP5 FZD7 FZD7 FZD6 FZD6 DKK4 DKK4 DVL3 DVL3 LDLR LDLR TCF7L2-2 TCF7L2-2 WNT8A WNT8A WNT4 WNT4 H3B5C9_LATCH H3B5C9_LATCH CTNNB1 CTNNB1 SOX17 SOX17 KREMEN1 KREMEN1 AMER1 AMER1 TCF7L2 TCF7L2 WNT2 WNT2 KLF8 KLF8 LOC102363206 LOC102363206 TCF7 TCF7 LOC102354692 LOC102354692 WNT9A WNT9A WNT10A WNT10A WNT6 WNT6 LOC102354118 LOC102354118 AXIN2 AXIN2 WNT3A WNT3A LOC102357156 LOC102357156 GPC4 GPC4 WNT5B WNT5B FZD2 FZD2 NLK NLK WNT2B WNT2B LRP6 LRP6 WNT8B WNT8B LRP5 LRP5 DVL1 DVL1 FZD10 FZD10 FZD9 FZD9 WNT1 WNT1 LOC102350297 LOC102350297 WNT10B WNT10B RELN RELN VLDLR VLDLR KLF3 KLF3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
BCL9BCL9 transcription coactivator. (1578 aa)
LRP1BUncharacterized protein. (1007 aa)
FZD8Frizzled class receptor 8; Belongs to the G-protein coupled receptor Fz/Smo family. (582 aa)
ROR2Receptor tyrosine kinase like orphan receptor 2; Belongs to the protein kinase superfamily. Tyr protein kinase family. ROR subfamily. (882 aa)
RYKReceptor like tyrosine kinase. (542 aa)
LRP8LDL receptor related protein 8. (842 aa)
FZD4Frizzled class receptor 4; Belongs to the G-protein coupled receptor Fz/Smo family. (530 aa)
H2ZXM4_LATCHEGF-like domain-containing protein. (580 aa)
TCF7L1Transcription factor 7 like 1. (438 aa)
H2ZYH3_LATCHProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (355 aa)
LOC102346005Uncharacterized protein. (727 aa)
H3A4P0_LATCHIg-like domain-containing protein. (174 aa)
UCKL1Uridine-cytidine kinase 1 like 1. (550 aa)
H3A5Z1_LATCHUncharacterized protein. (223 aa)
WLSWnt ligand secretion mediator. (541 aa)
LOC102358266Dickkopf WNT signaling pathway inhibitor 1b. (261 aa)
LEF1Lymphoid enhancer binding factor 1. (397 aa)
APCAPC regulator of WNT signaling pathway. (2802 aa)
H3A8H2_LATCHUncharacterized protein. (541 aa)
WNT7AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (349 aa)
WNT9BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (362 aa)
DKK2Dickkopf WNT signaling pathway inhibitor 2. (212 aa)
WNT5AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (381 aa)
WNT11Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (354 aa)
H3ABE1_LATCHUncharacterized protein. (86 aa)
H3ABR4_LATCHUncharacterized protein. (272 aa)
LOC102353948Nemo-like kinase, type 1. (336 aa)
LOC102350744RGS domain-containing protein. (110 aa)
CTNNBIP1Catenin beta interacting protein 1. (81 aa)
SFRP2Secreted frizzled related protein 2. (294 aa)
GSK3AGlycogen synthase kinase 3 alpha a; Belongs to the protein kinase superfamily. (463 aa)
H3ADZ3_LATCHRGS domain-containing protein. (163 aa)
BAMBIBMP and activin membrane-bound inhibitor homolog; Negatively regulates TGF-beta signaling. Belongs to the BAMBI family. (259 aa)
H3AF20_LATCHSi:ch211-243j20.2. (511 aa)
WNT16Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (357 aa)
PORCNPorcupine O-acyltransferase; Belongs to the membrane-bound acyltransferase family. (463 aa)
WNT3Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (331 aa)
APC2APC regulator of WNT signaling pathway 2. (2366 aa)
CSNK1A1Casein kinase 1 alpha 1. (287 aa)
SFRP1NTR domain-containing protein. (128 aa)
ROR1Receptor tyrosine kinase like orphan receptor 1. (769 aa)
LRP3LDL receptor related protein 3. (692 aa)
PCSK9Proprotein convertase subtilisin/kexin type 9. (672 aa)
PYGO2Pygopus family PHD finger 2. (401 aa)
SFRP1-2FZ domain-containing protein. (203 aa)
H3AP48_LATCHDickkopf_N domain-containing protein. (253 aa)
SOSTSclerostin. (210 aa)
LOC102348686Uncharacterized protein. (591 aa)
WIF1WNT inhibitory factor 1. (379 aa)
DKK3Dickkopf WNT signaling pathway inhibitor 3. (349 aa)
GSK3BGlycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily. (420 aa)
FZD3Frizzled class receptor 3; Belongs to the G-protein coupled receptor Fz/Smo family. (604 aa)
NDPCTCK domain-containing protein. (132 aa)
AXIN1Axin 1. (880 aa)
LDLRAP1Low density lipoprotein receptor adaptor protein 1b. (316 aa)
CTBP2C-terminal binding protein 2. (1002 aa)
H3AXS1_LATCHProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (313 aa)
TSPAN12Tetraspanin 12; Belongs to the tetraspanin (TM4SF) family. (236 aa)
FZD1Frizzled class receptor 1; Belongs to the G-protein coupled receptor Fz/Smo family. (557 aa)
LOC102359071Uncharacterized protein. (297 aa)
DAB1DAB adaptor protein 1. (484 aa)
CTBP1C-terminal binding protein 1; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (440 aa)
SFRP5Secreted frizzled related protein 5. (309 aa)
FZD7Frizzled class receptor 7; Belongs to the G-protein coupled receptor Fz/Smo family. (555 aa)
FZD6Frizzled class receptor 6; Belongs to the G-protein coupled receptor Fz/Smo family. (712 aa)
DKK4Dickkopf WNT signaling pathway inhibitor 4. (222 aa)
DVL3Dishevelled segment polarity protein 3. (716 aa)
LDLRLow density lipoprotein receptor. (851 aa)
TCF7L2-2Transcription factor 7 like 2. (180 aa)
WNT8AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (360 aa)
WNT4Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (355 aa)
H3B5C9_LATCHProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (351 aa)
CTNNB1Catenin beta 1. (781 aa)
SOX17SRY-box transcription factor 17. (381 aa)
KREMEN1Kringle containing transmembrane protein 1. (249 aa)
AMER1APC membrane recruitment protein 1. (900 aa)
TCF7L2Transcription factor 7 like 2. (439 aa)
WNT2Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (358 aa)
KLF8Kruppel like factor 8. (364 aa)
LOC102363206Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (575 aa)
TCF7Transcription factor 7. (343 aa)
LOC102354692Muscle-specific beta 1 integrin binding protein 2. (204 aa)
WNT9AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (341 aa)
WNT10AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (387 aa)
WNT6Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (348 aa)
LOC102354118Dickkopf_N domain-containing protein. (243 aa)
AXIN2Axin 2. (841 aa)
WNT3AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (367 aa)
LOC102357156Uncharacterized protein; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (445 aa)
GPC4Glypican 4; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family. (433 aa)
WNT5BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (378 aa)
FZD2Frizzled class receptor 2; Belongs to the G-protein coupled receptor Fz/Smo family. (552 aa)
NLKMitogen-activated protein kinase. (382 aa)
WNT2BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (370 aa)
LRP6Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. (1615 aa)
WNT8BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (432 aa)
LRP5Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. (1598 aa)
DVL1Dishevelled segment polarity protein 1. (552 aa)
FZD10Frizzled class receptor 10; Belongs to the G-protein coupled receptor Fz/Smo family. (580 aa)
FZD9Frizzled class receptor 9; Belongs to the G-protein coupled receptor Fz/Smo family. (583 aa)
WNT1Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (373 aa)
LOC102350297Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (354 aa)
WNT10BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (372 aa)
RELNReelin. (3462 aa)
VLDLRVery low density lipoprotein receptor. (885 aa)
KLF3Kruppel like factor 3. (337 aa)
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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