(17 nodes) beta-catenin-TCF complex, and C-terminal binding protein network (Latimeria chalumnae)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	BCL9	BCL9 transcription coactivator. (1578 aa)
	TCF7L1	Transcription factor 7 like 1. (438 aa)
	LEF1	Lymphoid enhancer binding factor 1. (397 aa)
	LOC102353948	Nemo-like kinase, type 1. (336 aa)
	PYGO2	Pygopus family PHD finger 2. (401 aa)
	CTBP2	C-terminal binding protein 2. (1002 aa)
	CTBP1	C-terminal binding protein 1; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (440 aa)
	TCF7L2-2	Transcription factor 7 like 2. (180 aa)
	CTNNB1	Catenin beta 1. (781 aa)
	SOX17	SRY-box transcription factor 17. (381 aa)
	TCF7L2	Transcription factor 7 like 2. (439 aa)
	KLF8	Kruppel like factor 8. (364 aa)
	TCF7	Transcription factor 7. (343 aa)
	LOC102354692	Muscle-specific beta 1 integrin binding protein 2. (204 aa)
	LOC102357156	Uncharacterized protein; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (445 aa)
	NLK	Mitogen-activated protein kinase. (382 aa)
	KLF3	Kruppel like factor 3. (337 aa)

Your Current Organism:

Latimeria chalumnae

NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BCL9	CTNNB1	ENSLACP00000000906	ENSLACP00000017209	BCL9 transcription coactivator.	Catenin beta 1.	0.977
BCL9	LEF1	ENSLACP00000000906	ENSLACP00000005598	BCL9 transcription coactivator.	Lymphoid enhancer binding factor 1.	0.772
BCL9	LOC102354692	ENSLACP00000000906	ENSLACP00000018915	BCL9 transcription coactivator.	Muscle-specific beta 1 integrin binding protein 2.	0.443
BCL9	PYGO2	ENSLACP00000000906	ENSLACP00000011098	BCL9 transcription coactivator.	Pygopus family PHD finger 2.	0.870
BCL9	TCF7	ENSLACP00000000906	ENSLACP00000018894	BCL9 transcription coactivator.	Transcription factor 7.	0.639
BCL9	TCF7L1	ENSLACP00000000906	ENSLACP00000002354	BCL9 transcription coactivator.	Transcription factor 7 like 1.	0.614
BCL9	TCF7L2	ENSLACP00000000906	ENSLACP00000017832	BCL9 transcription coactivator.	Transcription factor 7 like 2.	0.614
BCL9	TCF7L2-2	ENSLACP00000000906	ENSLACP00000016708	BCL9 transcription coactivator.	Transcription factor 7 like 2.	0.614
CTBP1	CTBP2	ENSLACP00000015411	ENSLACP00000013477	C-terminal binding protein 1; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	C-terminal binding protein 2.	0.901
CTBP1	CTNNB1	ENSLACP00000015411	ENSLACP00000017209	C-terminal binding protein 1; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	Catenin beta 1.	0.739
CTBP1	KLF3	ENSLACP00000015411	ENSLACP00000023332	C-terminal binding protein 1; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	Kruppel like factor 3.	0.788
CTBP1	KLF8	ENSLACP00000015411	ENSLACP00000018510	C-terminal binding protein 1; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	Kruppel like factor 8.	0.703
CTBP1	LEF1	ENSLACP00000015411	ENSLACP00000005598	C-terminal binding protein 1; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	Lymphoid enhancer binding factor 1.	0.954
CTBP1	LOC102357156	ENSLACP00000015411	ENSLACP00000019975	C-terminal binding protein 1; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	Uncharacterized protein; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	0.913
CTBP1	TCF7	ENSLACP00000015411	ENSLACP00000018894	C-terminal binding protein 1; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	Transcription factor 7.	0.575
CTBP1	TCF7L1	ENSLACP00000015411	ENSLACP00000002354	C-terminal binding protein 1; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	Transcription factor 7 like 1.	0.534
CTBP1	TCF7L2	ENSLACP00000015411	ENSLACP00000017832	C-terminal binding protein 1; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	Transcription factor 7 like 2.	0.534
CTBP1	TCF7L2-2	ENSLACP00000015411	ENSLACP00000016708	C-terminal binding protein 1; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	Transcription factor 7 like 2.	0.951
CTBP2	CTBP1	ENSLACP00000013477	ENSLACP00000015411	C-terminal binding protein 2.	C-terminal binding protein 1; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	0.901
CTBP2	CTNNB1	ENSLACP00000013477	ENSLACP00000017209	C-terminal binding protein 2.	Catenin beta 1.	0.739