STRINGSTRING
LOC102351518 LOC102351518 BMPR1B BMPR1B BMPR1A BMPR1A BMP10 BMP10 ACVR2A ACVR2A TGFBR2 TGFBR2 LOC102356523 LOC102356523 INHBA INHBA SMAD6 SMAD6 SMAD7 SMAD7 TGFBR3 TGFBR3 TGFB2 TGFB2 TGFBR1 TGFBR1 SMAD5 SMAD5 LOC102351081 LOC102351081 ACVR1C ACVR1C LOC102357009 LOC102357009 ZFYVE16 ZFYVE16 ACVR1 ACVR1 SMAD3 SMAD3 BMP6 BMP6 SMAD9 SMAD9 ZFYVE9 ZFYVE9 SMAD1 SMAD1 ACVR2B ACVR2B FST FST BMP2 BMP2 SMURF2 SMURF2 BMPR2 BMPR2 INHA INHA INHBB INHBB NODAL NODAL TGFB3 TGFB3 LOC102352268 LOC102352268 H3BEX6_LATCH H3BEX6_LATCH LOC102355609 LOC102355609 LOC102355877 LOC102355877 BMP4 BMP4 ACVRL1 ACVRL1 ACVR1B ACVR1B LOC102358988 LOC102358988 LOC102356233 LOC102356233
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LOC102351518Left-right determination factor. (364 aa)
BMPR1BSerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (532 aa)
BMPR1AReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (530 aa)
BMP10Bone morphogenetic protein 10. (405 aa)
ACVR2ASerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (512 aa)
TGFBR2TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (585 aa)
LOC102356523Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (510 aa)
INHBAInhibin subunit beta A. (390 aa)
SMAD6Mothers against decapentaplegic homolog. (485 aa)
SMAD7Mothers against decapentaplegic homolog. (377 aa)
TGFBR3Transforming growth factor beta receptor 3. (808 aa)
TGFB2Transforming growth factor beta; Belongs to the TGF-beta family. (415 aa)
TGFBR1Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (507 aa)
SMAD5Mothers against decapentaplegic homolog. (467 aa)
LOC102351081Bone morphogenetic protein 16. (396 aa)
ACVR1CReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (453 aa)
LOC102357009Southpaw. (414 aa)
ZFYVE16Zinc finger FYVE domain-containing protein. (1493 aa)
ACVR1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (506 aa)
SMAD3Mothers against decapentaplegic homolog. (358 aa)
BMP6Bone morphogenetic protein 6. (428 aa)
SMAD9Mothers against decapentaplegic homolog. (467 aa)
ZFYVE9Zinc finger FYVE domain-containing protein. (1429 aa)
SMAD1Mothers against decapentaplegic homolog. (465 aa)
ACVR2BSerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (515 aa)
FSTFollistatin. (319 aa)
BMP2Bone morphogenetic protein 2. (402 aa)
SMURF2E3 ubiquitin-protein ligase. (754 aa)
BMPR2Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1037 aa)
INHAInhibin alpha chain; Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition; Belongs to the TGF-beta family. (345 aa)
INHBBInhibin subunit beta B. (393 aa)
NODALTGF_BETA_2 domain-containing protein. (409 aa)
TGFB3Transforming growth factor beta; Belongs to the TGF-beta family. (409 aa)
LOC102352268Transforming growth factor beta; Belongs to the TGF-beta family. (414 aa)
H3BEX6_LATCHReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (307 aa)
LOC102355609TGF_BETA_2 domain-containing protein. (385 aa)
LOC102355877TGF_BETA_2 domain-containing protein. (359 aa)
BMP4Bone morphogenetic protein 4. (460 aa)
ACVRL1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (497 aa)
ACVR1BReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (489 aa)
LOC102358988Mothers against decapentaplegic homolog. (614 aa)
LOC102356233TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (574 aa)
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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