(17 nodes) Mixed, incl. F-BAR domain, and Polo kinase kinase network (Latimeria chalumnae)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	FNBP1	Formin binding protein 1. (574 aa)
	LOC102363928	Protein kinase domain-containing protein. (1197 aa)
	SLC6A3	Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (624 aa)
	USP20	Ubiquitin carboxyl-terminal hydrolase. (902 aa)
	LOC102355780	Si:ch211-11k18.4. (451 aa)
	TOR1B	Torsin. (332 aa)
	PDE4DIP	Phosphodiesterase 4D interacting protein. (2345 aa)
	PRRX2	Paired related homeobox 2. (166 aa)
	METTL11B	Methyltransferase like 11B. (294 aa)
	ARHGEF37	Rho guanine nucleotide exchange factor 37. (690 aa)
	FCHSD1	FCH and double SH3 domains 1. (721 aa)
	SLK	STE20 like kinase. (1174 aa)
	SNX22	Sorting nexin 22. (189 aa)
	PACSIN1	Protein kinase C and casein kinase substrate in neurons 1. (490 aa)
	PACSIN2	Protein kinase C and casein kinase substrate in neurons 2. (330 aa)
	LOC102353772	Si:dkey-98f17.5. (455 aa)
	PACSIN3	Protein kinase C and casein kinase substrate in neurons 3. (486 aa)

Your Current Organism:

Latimeria chalumnae

NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth

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structured XML interaction data, according to the 'PSI-MI' data standard

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a flat-file format describing the coordinates and colors of nodes in the network

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ARHGEF37	FCHSD1	ENSLACP00000010943	ENSLACP00000011661	Rho guanine nucleotide exchange factor 37.	FCH and double SH3 domains 1.	0.443
FCHSD1	ARHGEF37	ENSLACP00000011661	ENSLACP00000010943	FCH and double SH3 domains 1.	Rho guanine nucleotide exchange factor 37.	0.443
FCHSD1	FNBP1	ENSLACP00000011661	ENSLACP00000001088	FCH and double SH3 domains 1.	Formin binding protein 1.	0.543
FNBP1	FCHSD1	ENSLACP00000001088	ENSLACP00000011661	Formin binding protein 1.	FCH and double SH3 domains 1.	0.543
FNBP1	PRRX2	ENSLACP00000001088	ENSLACP00000008789	Formin binding protein 1.	Paired related homeobox 2.	0.499
FNBP1	SLC6A3	ENSLACP00000001088	ENSLACP00000002580	Formin binding protein 1.	Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.	0.499
FNBP1	SNX22	ENSLACP00000001088	ENSLACP00000017795	Formin binding protein 1.	Sorting nexin 22.	0.709
FNBP1	TOR1B	ENSLACP00000001088	ENSLACP00000007154	Formin binding protein 1.	Torsin.	0.726
FNBP1	USP20	ENSLACP00000001088	ENSLACP00000006041	Formin binding protein 1.	Ubiquitin carboxyl-terminal hydrolase.	0.701
METTL11B	PDE4DIP	ENSLACP00000009223	ENSLACP00000008163	Methyltransferase like 11B.	Phosphodiesterase 4D interacting protein.	0.872
METTL11B	PRRX2	ENSLACP00000009223	ENSLACP00000008789	Methyltransferase like 11B.	Paired related homeobox 2.	0.670
PACSIN1	PACSIN2	ENSLACP00000019394	ENSLACP00000019714	Protein kinase C and casein kinase substrate in neurons 1.	Protein kinase C and casein kinase substrate in neurons 2.	0.913
PACSIN1	PACSIN3	ENSLACP00000019394	ENSLACP00000021591	Protein kinase C and casein kinase substrate in neurons 1.	Protein kinase C and casein kinase substrate in neurons 3.	0.922
PACSIN1	SNX22	ENSLACP00000019394	ENSLACP00000017795	Protein kinase C and casein kinase substrate in neurons 1.	Sorting nexin 22.	0.580
PACSIN2	PACSIN1	ENSLACP00000019714	ENSLACP00000019394	Protein kinase C and casein kinase substrate in neurons 2.	Protein kinase C and casein kinase substrate in neurons 1.	0.913
PACSIN2	PACSIN3	ENSLACP00000019714	ENSLACP00000021591	Protein kinase C and casein kinase substrate in neurons 2.	Protein kinase C and casein kinase substrate in neurons 3.	0.923
PACSIN3	PACSIN1	ENSLACP00000021591	ENSLACP00000019394	Protein kinase C and casein kinase substrate in neurons 3.	Protein kinase C and casein kinase substrate in neurons 1.	0.922
PACSIN3	PACSIN2	ENSLACP00000021591	ENSLACP00000019714	Protein kinase C and casein kinase substrate in neurons 3.	Protein kinase C and casein kinase substrate in neurons 2.	0.923
PDE4DIP	METTL11B	ENSLACP00000008163	ENSLACP00000009223	Phosphodiesterase 4D interacting protein.	Methyltransferase like 11B.	0.872
PDE4DIP	PRRX2	ENSLACP00000008163	ENSLACP00000008789	Phosphodiesterase 4D interacting protein.	Paired related homeobox 2.	0.673