(45 nodes) Mixed, incl. Protein refolding, and DnaJ domain, conserved site network (Latimeria chalumnae)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	DNAJC2	DnaJ heat shock protein family (Hsp40) member C2. (620 aa)
	HSPA8	Uncharacterized protein; Belongs to the heat shock protein 70 family. (645 aa)
	LOC102367553	Heat shock protein family A (Hsp70) member 8; Belongs to the heat shock protein 70 family. (646 aa)
	DNAJB1	DnaJ heat shock protein family (Hsp40) member B1. (341 aa)
	DNAJB13	DnaJ heat shock protein family (Hsp40) member B13. (319 aa)
	NKTR	Natural killer cell triggering receptor. (1510 aa)
	DNAJA2	DnaJ heat shock protein family (Hsp40) member A2. (366 aa)
	DNAJC3	DnaJ heat shock protein family (Hsp40) member C3. (513 aa)
	H3A382_LATCH	Reverse transcriptase domain-containing protein. (680 aa)
	DNAJA1	DnaJ heat shock protein family (Hsp40) member A1. (359 aa)
	DNAJA3	DnaJ heat shock protein family (Hsp40) member A3. (480 aa)
	HSP90B1	Heat shock protein 90 beta family member 1. (800 aa)
	DNAJB14	DnaJ heat shock protein family (Hsp40) member B14. (381 aa)
	HSPA12A	Heat shock protein family A (Hsp70) member 12A. (665 aa)
	DNAJA4	DnaJ heat shock protein family (Hsp40) member A4. (396 aa)
	LOC102353228	Uncharacterized protein; Belongs to the heat shock protein 70 family. (648 aa)
	GRPEL2	GrpE like 2, mitochondrial; Belongs to the GrpE family. (225 aa)
	HSPA12B	Heat shock protein family A (Hsp70) member 12B. (680 aa)
	DNAJB2	DnaJ heat shock protein family (Hsp40) member B2. (299 aa)
	HSPA13	Heat shock protein family A (Hsp70) member 13. (326 aa)
	DNAJB11	DnaJ heat shock protein family (Hsp40) member B11. (299 aa)
	CLPB	ClpB homolog, mitochondrial AAA ATPase chaperonin. (425 aa)
	CDC37	Cell division cycle 37. (382 aa)
	HSPA9	Heat shock protein family A (Hsp70) member 9; Belongs to the heat shock protein 70 family. (647 aa)
	DNAJB9	DnaJ heat shock protein family (Hsp40) member B9. (219 aa)
	HSPA14	Heat shock protein 14; Belongs to the heat shock protein 70 family. (510 aa)
	GRPEL1	GrpE protein homolog; Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner; Belongs to the GrpE family. (220 aa)
	DNAJC5G	J domain-containing protein. (116 aa)
	LOC102357450	Uncharacterized protein; Belongs to the heat shock protein 70 family. (641 aa)
	TRAP1	TNF receptor associated protein 1. (718 aa)
	DNAJB4	DnaJ heat shock protein family (Hsp40) member B4. (343 aa)
	LOC102363778	J domain-containing protein. (211 aa)
	PPID	Peptidylprolyl isomerase D. (309 aa)
	HSP90AA1	Heat shock protein 90 alpha family class A member 1. (725 aa)
	LOC102351854	Uncharacterized protein; Belongs to the heat shock protein 70 family. (641 aa)
	LOC102359148	Uncharacterized protein; Belongs to the heat shock protein 70 family. (584 aa)
	HSPD1	Heat shock protein family D (Hsp60) member 1; Belongs to the chaperonin (HSP60) family. (565 aa)
	HSPE1	Heat shock protein family E (Hsp10) member 1; Belongs to the GroES chaperonin family. (114 aa)
	AHSA1	Activator of HSP90 ATPase activity 1. (341 aa)
	STIP1	Stress induced phosphoprotein 1. (576 aa)
	LOC102350613	Uncharacterized protein. (402 aa)
	HYOU1	Hypoxia up-regulated 1. (993 aa)
	HSPA5	Heat shock protein family A (Hsp70) member 5; Belongs to the heat shock protein 70 family. (654 aa)
	DNAJB5	DnaJ heat shock protein family (Hsp40) member B5. (348 aa)
	M3XLG5_LATCH	Uncharacterized protein. (384 aa)

Your Current Organism:

Latimeria chalumnae

NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AHSA1	CDC37	ENSLACP00000018090	ENSLACP00000009880	Activator of HSP90 ATPase activity 1.	Cell division cycle 37.	0.757
AHSA1	CLPB	ENSLACP00000018090	ENSLACP00000009565	Activator of HSP90 ATPase activity 1.	ClpB homolog, mitochondrial AAA ATPase chaperonin.	0.740
AHSA1	DNAJA1	ENSLACP00000018090	ENSLACP00000004746	Activator of HSP90 ATPase activity 1.	DnaJ heat shock protein family (Hsp40) member A1.	0.556
AHSA1	DNAJA2	ENSLACP00000018090	ENSLACP00000002651	Activator of HSP90 ATPase activity 1.	DnaJ heat shock protein family (Hsp40) member A2.	0.556
AHSA1	DNAJA3	ENSLACP00000018090	ENSLACP00000005367	Activator of HSP90 ATPase activity 1.	DnaJ heat shock protein family (Hsp40) member A3.	0.581
AHSA1	DNAJA4	ENSLACP00000018090	ENSLACP00000006389	Activator of HSP90 ATPase activity 1.	DnaJ heat shock protein family (Hsp40) member A4.	0.556
AHSA1	DNAJB1	ENSLACP00000018090	ENSLACP00000001606	Activator of HSP90 ATPase activity 1.	DnaJ heat shock protein family (Hsp40) member B1.	0.613
AHSA1	DNAJB13	ENSLACP00000018090	ENSLACP00000002136	Activator of HSP90 ATPase activity 1.	DnaJ heat shock protein family (Hsp40) member B13.	0.613
AHSA1	DNAJB2	ENSLACP00000018090	ENSLACP00000007287	Activator of HSP90 ATPase activity 1.	DnaJ heat shock protein family (Hsp40) member B2.	0.458
AHSA1	DNAJB4	ENSLACP00000018090	ENSLACP00000014689	Activator of HSP90 ATPase activity 1.	DnaJ heat shock protein family (Hsp40) member B4.	0.613
AHSA1	DNAJB5	ENSLACP00000018090	ENSLACP00000022000	Activator of HSP90 ATPase activity 1.	DnaJ heat shock protein family (Hsp40) member B5.	0.611
AHSA1	DNAJB9	ENSLACP00000018090	ENSLACP00000011504	Activator of HSP90 ATPase activity 1.	DnaJ heat shock protein family (Hsp40) member B9.	0.611
AHSA1	H3A382_LATCH	ENSLACP00000018090	ENSLACP00000004103	Activator of HSP90 ATPase activity 1.	Reverse transcriptase domain-containing protein.	0.628
AHSA1	HSP90AA1	ENSLACP00000018090	ENSLACP00000016328	Activator of HSP90 ATPase activity 1.	Heat shock protein 90 alpha family class A member 1.	0.887
AHSA1	HSP90B1	ENSLACP00000018090	ENSLACP00000005832	Activator of HSP90 ATPase activity 1.	Heat shock protein 90 beta family member 1.	0.883
AHSA1	HSPA12A	ENSLACP00000018090	ENSLACP00000006257	Activator of HSP90 ATPase activity 1.	Heat shock protein family A (Hsp70) member 12A.	0.406
AHSA1	HSPA12B	ENSLACP00000018090	ENSLACP00000007277	Activator of HSP90 ATPase activity 1.	Heat shock protein family A (Hsp70) member 12B.	0.406
AHSA1	HSPA13	ENSLACP00000018090	ENSLACP00000009124	Activator of HSP90 ATPase activity 1.	Heat shock protein family A (Hsp70) member 13.	0.406
AHSA1	HSPA14	ENSLACP00000018090	ENSLACP00000011750	Activator of HSP90 ATPase activity 1.	Heat shock protein 14; Belongs to the heat shock protein 70 family.	0.406
AHSA1	HSPA5	ENSLACP00000018090	ENSLACP00000020775	Activator of HSP90 ATPase activity 1.	Heat shock protein family A (Hsp70) member 5; Belongs to the heat shock protein 70 family.	0.688