(14 nodes) Mixed, incl. Regulation of commissural axon pathfinding by SLIT and ROBO, and Peptidase S28 network (Latimeria chalumnae)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	DYM	Dymeclin. (473 aa)
	EMP3	Epithelial membrane protein 3. (161 aa)
	RABL6	RAB, member RAS oncogene family like 6. (360 aa)
	ADAMTS13	ADAM metallopeptidase with thrombospondin type 1 motif 13. (1330 aa)
	GFI1B	Growth factor independent 1B transcriptional repressor. (327 aa)
	LOC102352767	VWFC domain-containing protein. (433 aa)
	H3B5B5_LATCH	Uncharacterized protein. (264 aa)
	KCNT1	Potassium sodium-activated channel subfamily T member 1. (1095 aa)
	CAMSAP1	Calmodulin regulated spectrin associated protein 1. (1614 aa)
	UBAC1	UBA domain containing 1. (405 aa)
	DPP7	Uncharacterized protein. (245 aa)
	MAPK8IP1	Mitogen-activated protein kinase 8 interacting protein 1. (704 aa)
	COL5A1	Collagen type V alpha 1 chain. (1742 aa)
	ZNF362	Zinc finger protein 362. (391 aa)

Your Current Organism:

Latimeria chalumnae

NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ADAMTS13	CAMSAP1	ENSLACP00000013489	ENSLACP00000018256	ADAM metallopeptidase with thrombospondin type 1 motif 13.	Calmodulin regulated spectrin associated protein 1.	0.506
ADAMTS13	KCNT1	ENSLACP00000013489	ENSLACP00000017582	ADAM metallopeptidase with thrombospondin type 1 motif 13.	Potassium sodium-activated channel subfamily T member 1.	0.503
ADAMTS13	UBAC1	ENSLACP00000013489	ENSLACP00000018555	ADAM metallopeptidase with thrombospondin type 1 motif 13.	UBA domain containing 1.	0.501
CAMSAP1	ADAMTS13	ENSLACP00000018256	ENSLACP00000013489	Calmodulin regulated spectrin associated protein 1.	ADAM metallopeptidase with thrombospondin type 1 motif 13.	0.506
CAMSAP1	KCNT1	ENSLACP00000018256	ENSLACP00000017582	Calmodulin regulated spectrin associated protein 1.	Potassium sodium-activated channel subfamily T member 1.	0.572
CAMSAP1	UBAC1	ENSLACP00000018256	ENSLACP00000018555	Calmodulin regulated spectrin associated protein 1.	UBA domain containing 1.	0.817
DPP7	RABL6	ENSLACP00000019402	ENSLACP00000008951	Uncharacterized protein.	RAB, member RAS oncogene family like 6.	0.709
DPP7	UBAC1	ENSLACP00000019402	ENSLACP00000018555	Uncharacterized protein.	UBA domain containing 1.	0.481
DYM	KCNT1	ENSLACP00000001271	ENSLACP00000017582	Dymeclin.	Potassium sodium-activated channel subfamily T member 1.	0.762
EMP3	GFI1B	ENSLACP00000003265	ENSLACP00000013865	Epithelial membrane protein 3.	Growth factor independent 1B transcriptional repressor.	0.570
EMP3	KCNT1	ENSLACP00000003265	ENSLACP00000017582	Epithelial membrane protein 3.	Potassium sodium-activated channel subfamily T member 1.	0.573
EMP3	LOC102352767	ENSLACP00000003265	ENSLACP00000015612	Epithelial membrane protein 3.	VWFC domain-containing protein.	0.573
EMP3	MAPK8IP1	ENSLACP00000003265	ENSLACP00000021064	Epithelial membrane protein 3.	Mitogen-activated protein kinase 8 interacting protein 1.	0.576
EMP3	ZNF362	ENSLACP00000003265	ENSLACP00000022091	Epithelial membrane protein 3.	Zinc finger protein 362.	0.667
GFI1B	EMP3	ENSLACP00000013865	ENSLACP00000003265	Growth factor independent 1B transcriptional repressor.	Epithelial membrane protein 3.	0.570
GFI1B	KCNT1	ENSLACP00000013865	ENSLACP00000017582	Growth factor independent 1B transcriptional repressor.	Potassium sodium-activated channel subfamily T member 1.	0.503
GFI1B	LOC102352767	ENSLACP00000013865	ENSLACP00000015612	Growth factor independent 1B transcriptional repressor.	VWFC domain-containing protein.	0.543
GFI1B	MAPK8IP1	ENSLACP00000013865	ENSLACP00000021064	Growth factor independent 1B transcriptional repressor.	Mitogen-activated protein kinase 8 interacting protein 1.	0.504
H3B5B5_LATCH	LOC102352767	ENSLACP00000017086	ENSLACP00000015612	Uncharacterized protein.	VWFC domain-containing protein.	0.900
KCNT1	ADAMTS13	ENSLACP00000017582	ENSLACP00000013489	Potassium sodium-activated channel subfamily T member 1.	ADAM metallopeptidase with thrombospondin type 1 motif 13.	0.503