(26 nodes) Claudin network (Latimeria chalumnae)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC102348856	Uncharacterized protein. (190 aa)
	CLDN18	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (276 aa)
	LOC102348536	Uncharacterized protein. (184 aa)
	LOC106705730	Uncharacterized protein. (200 aa)
	CLDN10	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (232 aa)
	LOC102365642	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (213 aa)
	LOC102352912	Uncharacterized protein. (209 aa)
	H3A812_LATCH	Uncharacterized protein. (193 aa)
	H3A9Z9_LATCH	Claudin 23a. (213 aa)
	CLDN7	Claudin 7b. (145 aa)
	LOC102352776	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (233 aa)
	CLDN14	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (235 aa)
	LOC102353037	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (233 aa)
	LOC102346705	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (213 aa)
	TTC14	Tetratricopeptide repeat domain 14. (783 aa)
	LOC102362746	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (210 aa)
	CLDN20	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (221 aa)
	CLDN2	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (238 aa)
	LOC102364939	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (208 aa)
	CLDN11	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (209 aa)
	CLDN1	Claudin 1. (210 aa)
	CLDN19	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (209 aa)
	LOC102362450	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (192 aa)
	CLDN34	Uncharacterized protein. (257 aa)
	LOC102360103	Uncharacterized protein. (172 aa)
	LOC102352367	Uncharacterized protein. (188 aa)

Your Current Organism:

Latimeria chalumnae

NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth

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structured XML interaction data, according to the 'PSI-MI' data standard

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node degree of proteins in your network (given the current score cut-off)

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a flat-file format describing the coordinates and colors of nodes in the network

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CLDN1	CLDN10	ENSLACP00000017569	ENSLACP00000005269	Claudin 1.	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	0.675
CLDN1	CLDN11	ENSLACP00000017569	ENSLACP00000016560	Claudin 1.	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	0.714
CLDN1	CLDN14	ENSLACP00000017569	ENSLACP00000012827	Claudin 1.	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	0.704
CLDN1	CLDN18	ENSLACP00000017569	ENSLACP00000004903	Claudin 1.	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	0.686
CLDN1	CLDN19	ENSLACP00000017569	ENSLACP00000020552	Claudin 1.	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	0.671
CLDN1	CLDN2	ENSLACP00000017569	ENSLACP00000014944	Claudin 1.	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	0.690
CLDN1	CLDN20	ENSLACP00000017569	ENSLACP00000014449	Claudin 1.	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	0.664
CLDN1	CLDN34	ENSLACP00000017569	ENSLACP00000022250	Claudin 1.	Uncharacterized protein.	0.650
CLDN1	CLDN7	ENSLACP00000017569	ENSLACP00000009714	Claudin 1.	Claudin 7b.	0.663
CLDN1	H3A812_LATCH	ENSLACP00000017569	ENSLACP00000005783	Claudin 1.	Uncharacterized protein.	0.748
CLDN1	H3A9Z9_LATCH	ENSLACP00000017569	ENSLACP00000006470	Claudin 1.	Claudin 23a.	0.710
CLDN1	LOC102346705	ENSLACP00000017569	ENSLACP00000013916	Claudin 1.	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	0.698
CLDN1	LOC102348536	ENSLACP00000017569	ENSLACP00000004957	Claudin 1.	Uncharacterized protein.	0.774
CLDN1	LOC102348856	ENSLACP00000017569	ENSLACP00000004079	Claudin 1.	Uncharacterized protein.	0.775
CLDN1	LOC102352367	ENSLACP00000017569	ENSLACP00000022365	Claudin 1.	Uncharacterized protein.	0.685
CLDN1	LOC102352776	ENSLACP00000017569	ENSLACP00000012735	Claudin 1.	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	0.694
CLDN1	LOC102352912	ENSLACP00000017569	ENSLACP00000005522	Claudin 1.	Uncharacterized protein.	0.676
CLDN1	LOC102353037	ENSLACP00000017569	ENSLACP00000012904	Claudin 1.	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	0.694
CLDN1	LOC102360103	ENSLACP00000017569	ENSLACP00000022309	Claudin 1.	Uncharacterized protein.	0.667
CLDN1	LOC102362450	ENSLACP00000017569	ENSLACP00000020610	Claudin 1.	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	0.746