(5 nodes) Heat shock protein Hsp90, conserved site, and Cdc37 network (Latimeria chalumnae)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC102357218	Heat shock protein 90, alpha (cytosolic), class A member 1, tandem duplicate 1. (730 aa)
	SUGT1	SGT1 homolog, MIS12 kinetochore complex assembly cochaperone. (336 aa)
	CDC37L1	Cell division cycle 37 like 1. (326 aa)
	HSP90AB1	Heat shock protein 90 alpha family class B member 1. (734 aa)
	H3B2N1_LATCH	NACHT domain-containing protein. (429 aa)

Your Current Organism:

Latimeria chalumnae

NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CDC37L1	HSP90AB1	ENSLACP00000005854	ENSLACP00000011759	Cell division cycle 37 like 1.	Heat shock protein 90 alpha family class B member 1.	0.845
CDC37L1	LOC102357218	ENSLACP00000005854	ENSLACP00000000818	Cell division cycle 37 like 1.	Heat shock protein 90, alpha (cytosolic), class A member 1, tandem duplicate 1.	0.845
CDC37L1	SUGT1	ENSLACP00000005854	ENSLACP00000005253	Cell division cycle 37 like 1.	SGT1 homolog, MIS12 kinetochore complex assembly cochaperone.	0.450
H3B2N1_LATCH	HSP90AB1	ENSLACP00000016152	ENSLACP00000011759	NACHT domain-containing protein.	Heat shock protein 90 alpha family class B member 1.	0.924
H3B2N1_LATCH	LOC102357218	ENSLACP00000016152	ENSLACP00000000818	NACHT domain-containing protein.	Heat shock protein 90, alpha (cytosolic), class A member 1, tandem duplicate 1.	0.924
H3B2N1_LATCH	SUGT1	ENSLACP00000016152	ENSLACP00000005253	NACHT domain-containing protein.	SGT1 homolog, MIS12 kinetochore complex assembly cochaperone.	0.938
HSP90AB1	CDC37L1	ENSLACP00000011759	ENSLACP00000005854	Heat shock protein 90 alpha family class B member 1.	Cell division cycle 37 like 1.	0.845
HSP90AB1	H3B2N1_LATCH	ENSLACP00000011759	ENSLACP00000016152	Heat shock protein 90 alpha family class B member 1.	NACHT domain-containing protein.	0.924
HSP90AB1	LOC102357218	ENSLACP00000011759	ENSLACP00000000818	Heat shock protein 90 alpha family class B member 1.	Heat shock protein 90, alpha (cytosolic), class A member 1, tandem duplicate 1.	0.900
HSP90AB1	SUGT1	ENSLACP00000011759	ENSLACP00000005253	Heat shock protein 90 alpha family class B member 1.	SGT1 homolog, MIS12 kinetochore complex assembly cochaperone.	0.990
LOC102357218	CDC37L1	ENSLACP00000000818	ENSLACP00000005854	Heat shock protein 90, alpha (cytosolic), class A member 1, tandem duplicate 1.	Cell division cycle 37 like 1.	0.845
LOC102357218	H3B2N1_LATCH	ENSLACP00000000818	ENSLACP00000016152	Heat shock protein 90, alpha (cytosolic), class A member 1, tandem duplicate 1.	NACHT domain-containing protein.	0.924
LOC102357218	HSP90AB1	ENSLACP00000000818	ENSLACP00000011759	Heat shock protein 90, alpha (cytosolic), class A member 1, tandem duplicate 1.	Heat shock protein 90 alpha family class B member 1.	0.900
LOC102357218	SUGT1	ENSLACP00000000818	ENSLACP00000005253	Heat shock protein 90, alpha (cytosolic), class A member 1, tandem duplicate 1.	SGT1 homolog, MIS12 kinetochore complex assembly cochaperone.	0.990
SUGT1	CDC37L1	ENSLACP00000005253	ENSLACP00000005854	SGT1 homolog, MIS12 kinetochore complex assembly cochaperone.	Cell division cycle 37 like 1.	0.450
SUGT1	H3B2N1_LATCH	ENSLACP00000005253	ENSLACP00000016152	SGT1 homolog, MIS12 kinetochore complex assembly cochaperone.	NACHT domain-containing protein.	0.938
SUGT1	HSP90AB1	ENSLACP00000005253	ENSLACP00000011759	SGT1 homolog, MIS12 kinetochore complex assembly cochaperone.	Heat shock protein 90 alpha family class B member 1.	0.990
SUGT1	LOC102357218	ENSLACP00000005253	ENSLACP00000000818	SGT1 homolog, MIS12 kinetochore complex assembly cochaperone.	Heat shock protein 90, alpha (cytosolic), class A member 1, tandem duplicate 1.	0.990