(5 nodes) MHC class I peptide loading complex network (Latimeria chalumnae)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	TAPBP	Uncharacterized protein. (453 aa)
	PDIA3	Protein disulfide-isomerase. (497 aa)
	TAP2	Transporter associated with antigen processing, subunit type a. (720 aa)
	TAP1	Transporter 1, ATP-binding cassette, sub-family B (MDR/TAP). (735 aa)
	CALR3	Calreticulin. (416 aa)

Your Current Organism:

Latimeria chalumnae

NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CALR3	PDIA3	ENSLACP00000020782	ENSLACP00000015133	Calreticulin.	Protein disulfide-isomerase.	0.998
CALR3	TAP1	ENSLACP00000020782	ENSLACP00000016040	Calreticulin.	Transporter 1, ATP-binding cassette, sub-family B (MDR/TAP).	0.939
CALR3	TAP2	ENSLACP00000020782	ENSLACP00000015839	Calreticulin.	Transporter associated with antigen processing, subunit type a.	0.947
CALR3	TAPBP	ENSLACP00000020782	ENSLACP00000010397	Calreticulin.	Uncharacterized protein.	0.993
PDIA3	CALR3	ENSLACP00000015133	ENSLACP00000020782	Protein disulfide-isomerase.	Calreticulin.	0.998
PDIA3	TAP1	ENSLACP00000015133	ENSLACP00000016040	Protein disulfide-isomerase.	Transporter 1, ATP-binding cassette, sub-family B (MDR/TAP).	0.951
PDIA3	TAP2	ENSLACP00000015133	ENSLACP00000015839	Protein disulfide-isomerase.	Transporter associated with antigen processing, subunit type a.	0.962
PDIA3	TAPBP	ENSLACP00000015133	ENSLACP00000010397	Protein disulfide-isomerase.	Uncharacterized protein.	0.997
TAP1	CALR3	ENSLACP00000016040	ENSLACP00000020782	Transporter 1, ATP-binding cassette, sub-family B (MDR/TAP).	Calreticulin.	0.939
TAP1	PDIA3	ENSLACP00000016040	ENSLACP00000015133	Transporter 1, ATP-binding cassette, sub-family B (MDR/TAP).	Protein disulfide-isomerase.	0.951
TAP1	TAP2	ENSLACP00000016040	ENSLACP00000015839	Transporter 1, ATP-binding cassette, sub-family B (MDR/TAP).	Transporter associated with antigen processing, subunit type a.	0.998
TAP1	TAPBP	ENSLACP00000016040	ENSLACP00000010397	Transporter 1, ATP-binding cassette, sub-family B (MDR/TAP).	Uncharacterized protein.	0.955
TAP2	CALR3	ENSLACP00000015839	ENSLACP00000020782	Transporter associated with antigen processing, subunit type a.	Calreticulin.	0.947
TAP2	PDIA3	ENSLACP00000015839	ENSLACP00000015133	Transporter associated with antigen processing, subunit type a.	Protein disulfide-isomerase.	0.962
TAP2	TAP1	ENSLACP00000015839	ENSLACP00000016040	Transporter associated with antigen processing, subunit type a.	Transporter 1, ATP-binding cassette, sub-family B (MDR/TAP).	0.998
TAP2	TAPBP	ENSLACP00000015839	ENSLACP00000010397	Transporter associated with antigen processing, subunit type a.	Uncharacterized protein.	0.971
TAPBP	CALR3	ENSLACP00000010397	ENSLACP00000020782	Uncharacterized protein.	Calreticulin.	0.993
TAPBP	PDIA3	ENSLACP00000010397	ENSLACP00000015133	Uncharacterized protein.	Protein disulfide-isomerase.	0.997
TAPBP	TAP1	ENSLACP00000010397	ENSLACP00000016040	Uncharacterized protein.	Transporter 1, ATP-binding cassette, sub-family B (MDR/TAP).	0.955
TAPBP	TAP2	ENSLACP00000010397	ENSLACP00000015839	Uncharacterized protein.	Transporter associated with antigen processing, subunit type a.	0.971