(66 nodes) Mixed, incl. Serine proteases, trypsin domain, and Common Pathway of Fibrin Clot Formation network (Latimeria chalumnae)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	H2ZS91_LATCH	Uncharacterized protein; Belongs to the peptidase S1 family. (293 aa)
	FABP1	Fatty acid binding protein 1. (98 aa)
	F10	Coagulation factor X. (475 aa)
	H2ZVR1_LATCH	Uncharacterized protein. (167 aa)
	F7	Coagulation factor VII. (439 aa)
	LOC102363505	Zgc:136461; Belongs to the peptidase S1 family. (227 aa)
	LOC102356587	Uncharacterized protein; Belongs to the peptidase S1 family. Plasminogen subfamily. (628 aa)
	H2ZYY1_LATCH	SERPIN domain-containing protein; Belongs to the serpin family. (430 aa)
	LOC102358196	Uncharacterized protein. (392 aa)
	F3	Coagulation factor III, tissue factor. (286 aa)
	AMBP	Alpha-1-microglobulin/bikunin precursor. (350 aa)
	SERPINA1	SERPIN domain-containing protein; Belongs to the serpin family. (418 aa)
	PROZ	Protein Z, vitamin K dependent plasma glycoprotein; Belongs to the peptidase S1 family. (431 aa)
	LOC102354865	Uncharacterized protein. (746 aa)
	LOC102357388	Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family. (265 aa)
	SERPINF2	Serpin family F member 2; Belongs to the serpin family. (394 aa)
	H3A2J8_LATCH	Uncharacterized protein. (204 aa)
	LOC102347143	Uncharacterized protein. (612 aa)
	SERPINE2	Serpin family E member 2; Belongs to the serpin family. (403 aa)
	SERPINE3	Serpin family E member 3; Belongs to the serpin family. (417 aa)
	SERPINE1	Serpin family E member 1; Belongs to the serpin family. (403 aa)
	CPB2	Carboxypeptidase B2. (426 aa)
	GZMM	Granzyme M; Belongs to the peptidase S1 family. (259 aa)
	FGG	Fibrinogen gamma chain. (376 aa)
	CPB1	Carboxypeptidase B1. (418 aa)
	FGA	Fibrinogen alpha chain. (723 aa)
	H3AEU3_LATCH	Peptidase S1 domain-containing protein. (288 aa)
	FGB	Fibrinogen beta chain. (454 aa)
	SERPINA10	Serpin family A member 10; Belongs to the serpin family. (427 aa)
	LOC102359481	Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family. (239 aa)
	LOC102358409	Uncharacterized protein. (534 aa)
	H3AJF8_LATCH	Peptidase S1 domain-containing protein. (483 aa)
	LOC102352835	Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family. (266 aa)
	PLAU	Uncharacterized protein. (469 aa)
	SERPIND1	Serpin family D member 1; Belongs to the serpin family. (538 aa)
	F9	Coagulation factor IX. (453 aa)
	LOC102348351	SERPIN domain-containing protein; Belongs to the serpin family. (453 aa)
	CLEC3B	C-type lectin domain family 3 member B. (200 aa)
	H3AVZ6_LATCH	Uncharacterized protein; Belongs to the peptidase S1 family. (527 aa)
	PLAT	Plasminogen activator; Belongs to the peptidase S1 family. (552 aa)
	F8	Coagulation factor VIII; Belongs to the multicopper oxidase family. (2173 aa)
	LOC102345227	Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family. (259 aa)
	PROC	Uncharacterized protein. (444 aa)
	H3B780_LATCH	Uncharacterized protein. (370 aa)
	SERPINC1	Serpin family C member 1; Belongs to the serpin family. (485 aa)
	F5	Coagulation factor V; Belongs to the multicopper oxidase family. (1780 aa)
	H3BCB7_LATCH	Uncharacterized protein; Belongs to the peptidase S1 family. (463 aa)
	AHSG	Alpha 2-HS glycoprotein. (252 aa)
	H3BES4_LATCH	Uncharacterized protein. (558 aa)
	LOC102354654	Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family. (271 aa)
	CTRC	Elastase 3 like; Belongs to the peptidase S1 family. (435 aa)
	LOC102355168	Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family. (272 aa)
	LOC102358369	Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family. (264 aa)
	F2	Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family. (618 aa)
	VTN	Vitronectin b. (492 aa)
	LOC102363384	Uncharacterized protein. (479 aa)
	CPE	Carboxypeptidase E. (469 aa)
	LOC106706381	Uncharacterized protein. (224 aa)
	LOC102351715	Uncharacterized protein. (1426 aa)
	APOH	Apolipoprotein H. (351 aa)
	MST1	Macrophage stimulating 1; Belongs to the peptidase S1 family. Plasminogen subfamily. (707 aa)
	LOC102348329	Secreted phosphoprotein 2. (184 aa)
	TTR	Transthyretin; Thyroid hormone-binding protein. Probably transports thyroxine from the bloodstream to the brain. (149 aa)
	PLG	Plasminogen; Belongs to the peptidase S1 family. Plasminogen subfamily. (725 aa)
	M3XL62_LATCH	Uncharacterized protein. (269 aa)
	LOC102352566	Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family. (266 aa)

Your Current Organism:

Latimeria chalumnae

NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth

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structured XML interaction data, according to the 'PSI-MI' data standard

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a flat-file format describing the coordinates and colors of nodes in the network

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AHSG	AMBP	ENSLACP00000020153	ENSLACP00000003553	Alpha 2-HS glycoprotein.	Alpha-1-microglobulin/bikunin precursor.	0.907
AHSG	APOH	ENSLACP00000020153	ENSLACP00000022592	Alpha 2-HS glycoprotein.	Apolipoprotein H.	0.921
AHSG	CPB2	ENSLACP00000020153	ENSLACP00000006320	Alpha 2-HS glycoprotein.	Carboxypeptidase B2.	0.426
AHSG	F2	ENSLACP00000020153	ENSLACP00000021404	Alpha 2-HS glycoprotein.	Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family.	0.965
AHSG	FABP1	ENSLACP00000020153	ENSLACP00000000844	Alpha 2-HS glycoprotein.	Fatty acid binding protein 1.	0.840
AHSG	FGA	ENSLACP00000020153	ENSLACP00000007992	Alpha 2-HS glycoprotein.	Fibrinogen alpha chain.	0.958
AHSG	FGB	ENSLACP00000020153	ENSLACP00000008521	Alpha 2-HS glycoprotein.	Fibrinogen beta chain.	0.827
AHSG	FGG	ENSLACP00000020153	ENSLACP00000007010	Alpha 2-HS glycoprotein.	Fibrinogen gamma chain.	0.901
AHSG	H2ZS91_LATCH	ENSLACP00000020153	ENSLACP00000000262	Alpha 2-HS glycoprotein.	Uncharacterized protein; Belongs to the peptidase S1 family.	0.556
AHSG	H2ZVR1_LATCH	ENSLACP00000020153	ENSLACP00000001482	Alpha 2-HS glycoprotein.	Uncharacterized protein.	0.679
AHSG	H3A2J8_LATCH	ENSLACP00000020153	ENSLACP00000003869	Alpha 2-HS glycoprotein.	Uncharacterized protein.	0.533
AHSG	LOC102347143	ENSLACP00000020153	ENSLACP00000004517	Alpha 2-HS glycoprotein.	Uncharacterized protein.	0.927
AHSG	LOC102348329	ENSLACP00000020153	ENSLACP00000023267	Alpha 2-HS glycoprotein.	Secreted phosphoprotein 2.	0.747
AHSG	LOC102351715	ENSLACP00000020153	ENSLACP00000022402	Alpha 2-HS glycoprotein.	Uncharacterized protein.	0.423
AHSG	LOC102356587	ENSLACP00000020153	ENSLACP00000002593	Alpha 2-HS glycoprotein.	Uncharacterized protein; Belongs to the peptidase S1 family. Plasminogen subfamily.	0.826
AHSG	LOC102358196	ENSLACP00000020153	ENSLACP00000002843	Alpha 2-HS glycoprotein.	Uncharacterized protein.	0.877
AHSG	LOC102358409	ENSLACP00000020153	ENSLACP00000009670	Alpha 2-HS glycoprotein.	Uncharacterized protein.	0.510
AHSG	PLG	ENSLACP00000020153	ENSLACP00000023309	Alpha 2-HS glycoprotein.	Plasminogen; Belongs to the peptidase S1 family. Plasminogen subfamily.	0.826
AHSG	SERPINA1	ENSLACP00000020153	ENSLACP00000003590	Alpha 2-HS glycoprotein.	SERPIN domain-containing protein; Belongs to the serpin family.	0.531
AHSG	SERPINA10	ENSLACP00000020153	ENSLACP00000009356	Alpha 2-HS glycoprotein.	Serpin family A member 10; Belongs to the serpin family.	0.502