(20 nodes) Serine proteases, trypsin domain, and Signaling by MST1 network (Latimeria chalumnae)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	H2ZS91_LATCH	Uncharacterized protein; Belongs to the peptidase S1 family. (293 aa)
	F10	Coagulation factor X. (475 aa)
	LOC102363505	Zgc:136461; Belongs to the peptidase S1 family. (227 aa)
	F3	Coagulation factor III, tissue factor. (286 aa)
	PROZ	Protein Z, vitamin K dependent plasma glycoprotein; Belongs to the peptidase S1 family. (431 aa)
	LOC102354865	Uncharacterized protein. (746 aa)
	GZMM	Granzyme M; Belongs to the peptidase S1 family. (259 aa)
	CPB1	Carboxypeptidase B1. (418 aa)
	H3AEU3_LATCH	Peptidase S1 domain-containing protein. (288 aa)
	H3AJF8_LATCH	Peptidase S1 domain-containing protein. (483 aa)
	H3AVZ6_LATCH	Uncharacterized protein; Belongs to the peptidase S1 family. (527 aa)
	LOC102345227	Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family. (259 aa)
	H3B780_LATCH	Uncharacterized protein. (370 aa)
	H3BCB7_LATCH	Uncharacterized protein; Belongs to the peptidase S1 family. (463 aa)
	H3BES4_LATCH	Uncharacterized protein. (558 aa)
	CTRC	Elastase 3 like; Belongs to the peptidase S1 family. (435 aa)
	LOC102358369	Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family. (264 aa)
	MST1	Macrophage stimulating 1; Belongs to the peptidase S1 family. Plasminogen subfamily. (707 aa)
	M3XL62_LATCH	Uncharacterized protein. (269 aa)
	LOC102352566	Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family. (266 aa)

Your Current Organism:

Latimeria chalumnae

NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CPB1	H3BCB7_LATCH	ENSLACP00000007087	ENSLACP00000019538	Carboxypeptidase B1.	Uncharacterized protein; Belongs to the peptidase S1 family.	0.568
CPB1	LOC102363505	ENSLACP00000007087	ENSLACP00000002520	Carboxypeptidase B1.	Zgc:136461; Belongs to the peptidase S1 family.	0.568
CTRC	PROZ	ENSLACP00000020705	ENSLACP00000003598	Elastase 3 like; Belongs to the peptidase S1 family.	Protein Z, vitamin K dependent plasma glycoprotein; Belongs to the peptidase S1 family.	0.488
F10	F3	ENSLACP00000001289	ENSLACP00000003507	Coagulation factor X.	Coagulation factor III, tissue factor.	0.601
F10	H2ZS91_LATCH	ENSLACP00000001289	ENSLACP00000000262	Coagulation factor X.	Uncharacterized protein; Belongs to the peptidase S1 family.	0.436
F3	F10	ENSLACP00000003507	ENSLACP00000001289	Coagulation factor III, tissue factor.	Coagulation factor X.	0.601
F3	H3B780_LATCH	ENSLACP00000003507	ENSLACP00000017751	Coagulation factor III, tissue factor.	Uncharacterized protein.	0.508
F3	H3BCB7_LATCH	ENSLACP00000003507	ENSLACP00000019538	Coagulation factor III, tissue factor.	Uncharacterized protein; Belongs to the peptidase S1 family.	0.444
F3	H3BES4_LATCH	ENSLACP00000003507	ENSLACP00000020395	Coagulation factor III, tissue factor.	Uncharacterized protein.	0.418
F3	LOC102363505	ENSLACP00000003507	ENSLACP00000002520	Coagulation factor III, tissue factor.	Zgc:136461; Belongs to the peptidase S1 family.	0.444
F3	M3XL62_LATCH	ENSLACP00000003507	ENSLACP00000023468	Coagulation factor III, tissue factor.	Uncharacterized protein.	0.508
F3	PROZ	ENSLACP00000003507	ENSLACP00000003598	Coagulation factor III, tissue factor.	Protein Z, vitamin K dependent plasma glycoprotein; Belongs to the peptidase S1 family.	0.601
GZMM	H2ZS91_LATCH	ENSLACP00000006590	ENSLACP00000000262	Granzyme M; Belongs to the peptidase S1 family.	Uncharacterized protein; Belongs to the peptidase S1 family.	0.401
GZMM	H3BCB7_LATCH	ENSLACP00000006590	ENSLACP00000019538	Granzyme M; Belongs to the peptidase S1 family.	Uncharacterized protein; Belongs to the peptidase S1 family.	0.593
GZMM	LOC102363505	ENSLACP00000006590	ENSLACP00000002520	Granzyme M; Belongs to the peptidase S1 family.	Zgc:136461; Belongs to the peptidase S1 family.	0.586
GZMM	M3XL62_LATCH	ENSLACP00000006590	ENSLACP00000023468	Granzyme M; Belongs to the peptidase S1 family.	Uncharacterized protein.	0.453
H2ZS91_LATCH	F10	ENSLACP00000000262	ENSLACP00000001289	Uncharacterized protein; Belongs to the peptidase S1 family.	Coagulation factor X.	0.436
H2ZS91_LATCH	GZMM	ENSLACP00000000262	ENSLACP00000006590	Uncharacterized protein; Belongs to the peptidase S1 family.	Granzyme M; Belongs to the peptidase S1 family.	0.401
H2ZS91_LATCH	H3AEU3_LATCH	ENSLACP00000000262	ENSLACP00000008164	Uncharacterized protein; Belongs to the peptidase S1 family.	Peptidase S1 domain-containing protein.	0.633
H2ZS91_LATCH	H3AJF8_LATCH	ENSLACP00000000262	ENSLACP00000009779	Uncharacterized protein; Belongs to the peptidase S1 family.	Peptidase S1 domain-containing protein.	0.429