(53 nodes) Ion transport by P-type ATPases, and Ubiquinone and other terpenoid-quinone biosynthesis network (Latimeria chalumnae)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ATP1A2	Sodium/potassium-transporting ATPase subunit alpha. (780 aa)
	H2ZU49_LATCH	Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1044 aa)
	H2ZU94_LATCH	PhoLip_ATPase_N domain-containing protein. (142 aa)
	ATP1A1	Sodium/potassium-transporting ATPase subunit alpha. (1033 aa)
	ATP8A1	ATPase phospholipid transporting 8A1. (347 aa)
	H3A0H2_LATCH	Uncharacterized protein. (148 aa)
	ATP4A	Sodium/potassium-transporting ATPase subunit alpha. (1033 aa)
	MSTO1	Misato mitochondrial distribution and morphology regulator 1. (555 aa)
	TMEM63A	Transmembrane protein 63A. (453 aa)
	ATP10D	Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily. (1483 aa)
	GGCX	Gamma-glutamyl carboxylase. (684 aa)
	LOC102350213	Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily. (1192 aa)
	ATP9B	Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily. (790 aa)
	PHF20L1	PHD finger protein 20 like 1. (1024 aa)
	ATP1B3	Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (280 aa)
	GPR78	G protein-coupled receptor 78b. (339 aa)
	LOC102353242	Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1171 aa)
	TMEM30A	Cell cycle control protein; Belongs to the CDC50/LEM3 family. (375 aa)
	H3ACZ6_LATCH	Uncharacterized protein. (158 aa)
	ATP1B4	Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (324 aa)
	ATP2B3	Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1259 aa)
	TMEM30B	Cell cycle control protein; Belongs to the CDC50/LEM3 family. (341 aa)
	ATP2C2	ATPase secretory pathway Ca2+ transporting 2; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. (765 aa)
	TMEM63B	Transmembrane protein 63B. (832 aa)
	NQO1	NAD(P)H quinone dehydrogenase 1. (254 aa)
	ATP11A	Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily. (1132 aa)
	ATP2C1	Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (901 aa)
	ATP11C	Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily. (1129 aa)
	LOC102357927	VKc domain-containing protein. (176 aa)
	ATP2A1	ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 1; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. (1013 aa)
	TMCO3	Transmembrane and coiled-coil domains 3. (679 aa)
	H3ATR2_LATCH	Uncharacterized protein. (282 aa)
	ATP2B4	Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1233 aa)
	ATP4B	Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (293 aa)
	LOC102364374	Cation-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily. (1154 aa)
	ATP1A3	Sodium/potassium-transporting ATPase subunit alpha. (1027 aa)
	TMEM165	Transmembrane protein 165. (420 aa)
	H3B102_LATCH	Cation_ATPase_C domain-containing protein; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. (176 aa)
	H3B195_LATCH	Cation/H+ exchanger protein 2; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (766 aa)
	NQO2	N-ribosyldihydronicotinamide:quinone reductase 2. (232 aa)
	ATP1B1	Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (305 aa)
	ATP8B4	Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily. (1159 aa)
	ATP10A	Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily. (1043 aa)
	ATP13A1	Cation-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily. (1192 aa)
	ZNF280D	Uncharacterized protein. (959 aa)
	ASCL3	Achaete-scute family bHLH transcription factor 3. (170 aa)
	LOC102367479	Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (992 aa)
	VKORC1L1	Vitamin K epoxide reductase complex subunit 1 like 1. (175 aa)
	LOC102359098	Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1180 aa)
	ATP8B3	Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily. (1206 aa)
	ATP2A2	Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1007 aa)
	LOC102359099	Cell cycle control protein; Belongs to the CDC50/LEM3 family. (352 aa)
	LOC102366069	Uncharacterized protein. (232 aa)

Your Current Organism:

Latimeria chalumnae

NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ATP10A	H2ZU94_LATCH	ENSLACP00000017480	ENSLACP00000000965	Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.	PhoLip_ATPase_N domain-containing protein.	0.901
ATP10A	LOC102359099	ENSLACP00000017480	ENSLACP00000022426	Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.	Cell cycle control protein; Belongs to the CDC50/LEM3 family.	0.578
ATP10A	TMEM30A	ENSLACP00000017480	ENSLACP00000006896	Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.	Cell cycle control protein; Belongs to the CDC50/LEM3 family.	0.578
ATP10A	TMEM30B	ENSLACP00000017480	ENSLACP00000007953	Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.	Cell cycle control protein; Belongs to the CDC50/LEM3 family.	0.578
ATP10D	LOC102359099	ENSLACP00000004655	ENSLACP00000022426	Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.	Cell cycle control protein; Belongs to the CDC50/LEM3 family.	0.578
ATP10D	TMEM30A	ENSLACP00000004655	ENSLACP00000006896	Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.	Cell cycle control protein; Belongs to the CDC50/LEM3 family.	0.578
ATP10D	TMEM30B	ENSLACP00000004655	ENSLACP00000007953	Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.	Cell cycle control protein; Belongs to the CDC50/LEM3 family.	0.578
ATP11A	ATP1B4	ENSLACP00000009193	ENSLACP00000007554	Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.	Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family.	0.525
ATP11A	LOC102359099	ENSLACP00000009193	ENSLACP00000022426	Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.	Cell cycle control protein; Belongs to the CDC50/LEM3 family.	0.743
ATP11A	TMEM30A	ENSLACP00000009193	ENSLACP00000006896	Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.	Cell cycle control protein; Belongs to the CDC50/LEM3 family.	0.743
ATP11A	TMEM30B	ENSLACP00000009193	ENSLACP00000007953	Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.	Cell cycle control protein; Belongs to the CDC50/LEM3 family.	0.656
ATP11C	ATP1B4	ENSLACP00000009686	ENSLACP00000007554	Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.	Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family.	0.439
ATP11C	LOC102359099	ENSLACP00000009686	ENSLACP00000022426	Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.	Cell cycle control protein; Belongs to the CDC50/LEM3 family.	0.914
ATP11C	TMEM30A	ENSLACP00000009686	ENSLACP00000006896	Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.	Cell cycle control protein; Belongs to the CDC50/LEM3 family.	0.914
ATP11C	TMEM30B	ENSLACP00000009686	ENSLACP00000007953	Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.	Cell cycle control protein; Belongs to the CDC50/LEM3 family.	0.656
ATP13A1	ATP1B1	ENSLACP00000018135	ENSLACP00000016128	Cation-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily.	Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family.	0.401
ATP13A1	ATP1B3	ENSLACP00000018135	ENSLACP00000005948	Cation-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily.	Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family.	0.470
ATP13A1	ATP1B4	ENSLACP00000018135	ENSLACP00000007554	Cation-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily.	Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family.	0.401
ATP13A1	ATP4B	ENSLACP00000018135	ENSLACP00000013673	Cation-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily.	Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family.	0.401
ATP13A1	H3ATR2_LATCH	ENSLACP00000018135	ENSLACP00000013033	Cation-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily.	Uncharacterized protein.	0.470