STRINGSTRING
ISCA1 ISCA1 GLRX3 GLRX3 LOC102354972 LOC102354972 ISCU ISCU CIAPIN1 CIAPIN1 BOLA1 BOLA1 SCLY SCLY MOCOS MOCOS NDOR1 NDOR1 LOC102366769 LOC102366769 FXN FXN NFU1 NFU1 ISCA2 ISCA2 NFS1 NFS1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ISCA1Iron-sulfur cluster assembly 1. (102 aa)
GLRX3Glutaredoxin 3. (332 aa)
LOC102354972Uncharacterized protein; Belongs to the BolA/IbaG family. (86 aa)
ISCUIron-sulfur cluster assembly enzyme; Scaffold protein for the de novo synthesis of iron-sulfur (Fe-S) clusters within mitochondria, which is required for maturation of both mitochondrial and cytoplasmic [2Fe-2S] and [4Fe-4S] proteins. (170 aa)
CIAPIN1Cytokine induced apoptosis inhibitor 1. (228 aa)
BOLA1BolA family member 1; Belongs to the BolA/IbaG family. (145 aa)
SCLYSelenocysteine lyase. (381 aa)
MOCOSMolybdenum cofactor sulfurase; Sulfurates the molybdenum cofactor. Sulfation of molybdenum is essential for xanthine dehydrogenase (XDH) and aldehyde oxidase (ADO) enzymes in which molybdenum cofactor is liganded by 1 oxygen and 1 sulfur atom in active form. (800 aa)
NDOR1NADPH-dependent diflavin oxidoreductase 1; Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery. Required for the maturation of extramitochondrial Fe-S proteins. Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis. Transfers electrons from NADPH to the Fe/S cluster of CIAPIN1. In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family. (597 aa)
LOC102366769Nfu_N domain-containing protein. (266 aa)
FXNFrataxin. (194 aa)
NFU1NFU1 iron-sulfur cluster scaffold homolog (S. cerevisiae). (253 aa)
ISCA2Iron-sulfur cluster assembly 2. (184 aa)
NFS1NFS1 cysteine desulfurase. (449 aa)
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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