(48 nodes) Mixed, incl. Oligosaccharyltransferase complex, and Cotranslational protein targeting to membrane network (Latimeria chalumnae)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

Your Input:
	MAN2B2	Alpha-mannosidase. (890 aa)
	LOC102356975	Uncharacterized protein. (207 aa)
	CLGN	Calmegin. (619 aa)
	DAD1	Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1; Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol- pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the [...] (113 aa)
	MOGS	Mannosyl-oligosaccharide glucosidase. (839 aa)
	LOC102353958	Translocating chain-associated membrane protein; Belongs to the TRAM family. (371 aa)
	GANC	Gal_mutarotas_2 domain-containing protein; Belongs to the glycosyl hydrolase 31 family. (916 aa)
	DDOST	Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit; Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol- pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across t [...] (447 aa)
	UGGT2	UDP-glucose glycoprotein glucosyltransferase 2. (1295 aa)
	SSR2	Signal sequence receptor subunit 2. (137 aa)
	OSTC	Oligosaccharyltransferase complex subunit; Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol- pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All s [...] (201 aa)
	GNPTAB	N-acetylglucosamine-1-phosphate transferase subunits alpha and beta. (1259 aa)
	SSR4	Signal sequence receptor subunit 4. (175 aa)
	STT3B	STT3 oligosaccharyltransferase complex catalytic subunit B. (816 aa)
	GNPTG	N-acetylglucosamine-1-phosphate transferase subunit gamma. (310 aa)
	KRTCAP2	Keratinocyte associated protein 2. (136 aa)
	MYORG	Myogenesis regulating glycosidase (putative); Belongs to the glycosyl hydrolase 31 family. (656 aa)
	FAM149A	Family with sequence similarity 149 member A. (596 aa)
	STK39	Serine/threonine kinase 39. (493 aa)
	LOC102364562	EF-hand domain-containing protein. (568 aa)
	RPN2	Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2; Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol- pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the en [...] (668 aa)
	SSR3	Signal sequence receptor subunit 3. (188 aa)
	LOC102366792	Si:ch73-12o23.1; Belongs to the glycosyl hydrolase 31 family. (856 aa)
	TUSC3	Tumor suppressor candidate 3. (336 aa)
	MAGT1	Magnesium transporter 1. (336 aa)
	LOC102350473	Tyrosine hydroxylase 2. (425 aa)
	SSR1	Signal sequence receptor subunit 1. (295 aa)
	SEC61A1	SEC61 translocon alpha 1 subunit; Belongs to the SecY/SEC61-alpha family. (471 aa)
	H3AYA9_LATCH	Protein kinase domain-containing protein. (357 aa)
	CAGE1	Uncharacterized protein. (951 aa)
	LOC102346649	Dol-P-Glc:Glc(2)Man(9)GlcNAc(2)-PP-Dol alpha-1,2-glucosyltransferase. (473 aa)
	SEC63	SEC63 homolog, protein translocation regulator. (763 aa)
	SEC62	SEC62 homolog, preprotein translocation factor. (413 aa)
	RPN1	Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1; Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol- pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the en [...] (599 aa)
	PRKCSH	Protein kinase C substrate 80K-H. (497 aa)
	STT3A	STT3 oligosaccharyltransferase complex catalytic subunit A. (622 aa)
	MAN2C1	Mannosidase alpha class 2C member 1. (1003 aa)
	SEC61A2	SEC61 translocon alpha 2 subunit. (505 aa)
	MAN1B1	alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family. (641 aa)
	GANAB	Glucosidase II alpha subunit; Belongs to the glycosyl hydrolase 31 family. (942 aa)
	TRAM1	Translocating chain-associated membrane protein; Belongs to the TRAM family. (370 aa)
	TRAM2	Translocating chain-associated membrane protein; Belongs to the TRAM family. (373 aa)
	GAA	Glucosidase alpha, acid; Belongs to the glycosyl hydrolase 31 family. (888 aa)
	MLEC	Malectin. (288 aa)
	LOC102349329	Uncharacterized protein. (293 aa)
	LOC102359920	Si:ch211-236l14.4; Belongs to the glycosyl hydrolase 31 family. (690 aa)
	TMEM258	Transmembrane protein 258. (79 aa)
	LOC102367070	Uncharacterized protein. (1093 aa)

Your Current Organism:

Latimeria chalumnae

NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CAGE1	DAD1	ENSLACP00000014819	ENSLACP00000003893	Uncharacterized protein.	Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1; Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol- pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the [...]	0.491
CAGE1	DDOST	ENSLACP00000014819	ENSLACP00000006059	Uncharacterized protein.	Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit; Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol- pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across t [...]	0.612
CAGE1	OSTC	ENSLACP00000014819	ENSLACP00000007357	Uncharacterized protein.	Oligosaccharyltransferase complex subunit; Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol- pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All s [...]	0.533
CAGE1	RPN1	ENSLACP00000014819	ENSLACP00000017803	Uncharacterized protein.	Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1; Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol- pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the en [...]	0.673
CAGE1	RPN2	ENSLACP00000014819	ENSLACP00000011031	Uncharacterized protein.	Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2; Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol- pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the en [...]	0.667
CAGE1	SEC61A1	ENSLACP00000014819	ENSLACP00000014489	Uncharacterized protein.	SEC61 translocon alpha 1 subunit; Belongs to the SecY/SEC61-alpha family.	0.585
CAGE1	SEC61A2	ENSLACP00000014819	ENSLACP00000018957	Uncharacterized protein.	SEC61 translocon alpha 2 subunit.	0.585
CAGE1	SEC63	ENSLACP00000014819	ENSLACP00000016449	Uncharacterized protein.	SEC63 homolog, protein translocation regulator.	0.525
CAGE1	SSR2	ENSLACP00000014819	ENSLACP00000006475	Uncharacterized protein.	Signal sequence receptor subunit 2.	0.865
CAGE1	SSR3	ENSLACP00000014819	ENSLACP00000012280	Uncharacterized protein.	Signal sequence receptor subunit 3.	0.876
CAGE1	SSR4	ENSLACP00000014819	ENSLACP00000008098	Uncharacterized protein.	Signal sequence receptor subunit 4.	0.763
CAGE1	STT3A	ENSLACP00000014819	ENSLACP00000018887	Uncharacterized protein.	STT3 oligosaccharyltransferase complex catalytic subunit A.	0.609
CAGE1	STT3B	ENSLACP00000014819	ENSLACP00000008577	Uncharacterized protein.	STT3 oligosaccharyltransferase complex catalytic subunit B.	0.441
CLGN	DDOST	ENSLACP00000002710	ENSLACP00000006059	Calmegin.	Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit; Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol- pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across t [...]	0.662
CLGN	GAA	ENSLACP00000002710	ENSLACP00000020242	Calmegin.	Glucosidase alpha, acid; Belongs to the glycosyl hydrolase 31 family.	0.555
CLGN	GANAB	ENSLACP00000002710	ENSLACP00000019643	Calmegin.	Glucosidase II alpha subunit; Belongs to the glycosyl hydrolase 31 family.	0.880
CLGN	GANC	ENSLACP00000002710	ENSLACP00000004549	Calmegin.	Gal_mutarotas_2 domain-containing protein; Belongs to the glycosyl hydrolase 31 family.	0.555
CLGN	LOC102359920	ENSLACP00000002710	ENSLACP00000021360	Calmegin.	Si:ch211-236l14.4; Belongs to the glycosyl hydrolase 31 family.	0.555
CLGN	LOC102366792	ENSLACP00000002710	ENSLACP00000012544	Calmegin.	Si:ch73-12o23.1; Belongs to the glycosyl hydrolase 31 family.	0.555
CLGN	MAGT1	ENSLACP00000002710	ENSLACP00000013440	Calmegin.	Magnesium transporter 1.	0.497