STRINGSTRING
LOC102361787 LOC102361787 ADPGK ADPGK GPI GPI ACO1 ACO1 PGM1 PGM1 IREB2 IREB2 GOT2 GOT2 BCKDHB BCKDHB H2ZXP4_LATCH H2ZXP4_LATCH ENO2 ENO2 URB2 URB2 DLD DLD H3A0F4_LATCH H3A0F4_LATCH RPIA RPIA ACLY ACLY SUCLG1 SUCLG1 PARP8 PARP8 RBKS RBKS RBM45 RBM45 GAPDHS GAPDHS IDH3A IDH3A PKM PKM TPI1 TPI1 HK3 HK3 SDHA SDHA RNASEH1 RNASEH1 IDH3G IDH3G FH FH LOC102362883 LOC102362883 PGLS PGLS H3AHJ0_LATCH H3AHJ0_LATCH H3AIU3_LATCH H3AIU3_LATCH DERA DERA LDHB LDHB H3AK14_LATCH H3AK14_LATCH PARP6 PARP6 ALDOC ALDOC ME3 ME3 SUCLA2 SUCLA2 H3ALR0_LATCH H3ALR0_LATCH ALDOA ALDOA HK1 HK1 L2HGDH L2HGDH DDO DDO ME2 ME2 FBP1 FBP1 PDHX PDHX LDHA LDHA OGDHL OGDHL H3AQW3_LATCH H3AQW3_LATCH FBP2 FBP2 PDHA1 PDHA1 GAPDH GAPDH PFKFB1 PFKFB1 ACO2 ACO2 PDHB PDHB GCK GCK SDHC SDHC PGK1 PGK1 TKTL2 TKTL2 PFKP PFKP PGD PGD SUCLG2 SUCLG2 DBT DBT FBXL5 FBXL5 LOC102350445 LOC102350445 GOT1 GOT1 H3B2X1_LATCH H3B2X1_LATCH BPGM BPGM IDH1 IDH1 H6PD H6PD ENO3 ENO3 PGAM2 PGAM2 DLAT DLAT NAGS NAGS ENO1 ENO1 LOC102363309 LOC102363309 SDHD SDHD SDHB SDHB DHTKD1 DHTKD1 TALDO1 TALDO1 MDH1 MDH1 H3BAN4_LATCH H3BAN4_LATCH H3BB55_LATCH H3BB55_LATCH HK2 HK2 LOC102349397 LOC102349397 PFKFB3 PFKFB3 LOC102354033 LOC102354033 PCK1 PCK1 IDH2 IDH2 TIGAR TIGAR BCKDHA BCKDHA MDH2 MDH2 PC PC PFKFB2 PFKFB2 DLST DLST CS CS PFKM PFKM G6PC G6PC TKT TKT IDH3B IDH3B MYCBPAP MYCBPAP ALDOB ALDOB G6PD G6PD G6PC2 G6PC2 PKLR PKLR GOT1L1 GOT1L1
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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LOC102361787Aminotran_1_2 domain-containing protein. (285 aa)
ADPGKADP dependent glucokinase. (479 aa)
GPIGlucose-6-phosphate isomerase; Belongs to the GPI family. (555 aa)
ACO1Aconitase 1. (673 aa)
PGM1Phosphoglucomutase 1; Belongs to the phosphohexose mutase family. (593 aa)
IREB2Iron responsive element binding protein 2. (965 aa)
GOT2Aspartate aminotransferase. (392 aa)
BCKDHBBranched chain keto acid dehydrogenase E1 subunit beta. (217 aa)
H2ZXP4_LATCHUncharacterized protein. (727 aa)
ENO2Enolase 2. (376 aa)
URB2URB2 ribosome biogenesis homolog. (1538 aa)
DLDDihydrolipoamide dehydrogenase. (236 aa)
H3A0F4_LATCHRibulose-phosphate 3-epimerase; Belongs to the ribulose-phosphate 3-epimerase family. (232 aa)
RPIAUncharacterized protein. (92 aa)
ACLYATP citrate lyase. (978 aa)
SUCLG1Succinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and specificity for either ATP or GTP is provided by different beta subunits. (335 aa)
PARP8Poly [ADP-ribose] polymerase. (775 aa)
RBKSRibokinase; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway. (317 aa)
RBM45RNA binding motif protein 45. (478 aa)
GAPDHSGlyceraldehyde-3-phosphate dehydrogenase. (396 aa)
IDH3AIsocitrate dehydrogenase [NAD] subunit, mitochondrial. (366 aa)
PKMPyruvate kinase; Belongs to the pyruvate kinase family. (539 aa)
TPI1Triosephosphate isomerase; Triosephosphate isomerase is an extremely efficient metabolic enzyme that catalyzes the interconversion between dihydroxyacetone phosphate (DHAP) and D-glyceraldehyde-3-phosphate (G3P) in glycolysis and gluconeogenesis. (262 aa)
HK3Hexokinase 3. (908 aa)
SDHASuccinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial; Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). (670 aa)
RNASEH1Ribonuclease H1; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. (310 aa)
IDH3GIsocitrate dehydrogenase [NAD] subunit, mitochondrial. (400 aa)
FHFumarate hydratase. (491 aa)
LOC102362883Iso_dh domain-containing protein. (384 aa)
PGLS6-phosphogluconolactonase; Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate. (254 aa)
H3AHJ0_LATCHPoly [ADP-ribose] polymerase. (214 aa)
H3AIU3_LATCHDihydrolipoamide dehydrogenase. (233 aa)
DERADeoxyribose-phosphate aldolase. (320 aa)
LDHBL-lactate dehydrogenase; Belongs to the LDH/MDH superfamily. (361 aa)
H3AK14_LATCHUncharacterized protein. (177 aa)
PARP6Poly (ADP-ribose) polymerase family, member 6a. (356 aa)
ALDOCFructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family. (340 aa)
ME3Malic enzyme. (617 aa)
SUCLA2Succinate-CoA ligase ADP-forming beta subunit. (374 aa)
H3ALR0_LATCHEnolase_N domain-containing protein. (322 aa)
ALDOAFructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family. (364 aa)
HK1Hexokinase 1. (919 aa)
L2HGDHL-2-hydroxyglutarate dehydrogenase. (419 aa)
DDOD-aspartate oxidase. (338 aa)
ME2Malic enzyme. (543 aa)
FBP1Fructose-bisphosphatase 1; Belongs to the FBPase class 1 family. (338 aa)
PDHXDihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex. (534 aa)
LDHAL-lactate dehydrogenase. (362 aa)
OGDHLOxoglutarate dehydrogenase like. (1017 aa)
H3AQW3_LATCHZgc:113208. (209 aa)
FBP2Fructose-bisphosphatase 2; Belongs to the FBPase class 1 family. (302 aa)
PDHA1Pyruvate dehydrogenase E1 component subunit alpha; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (400 aa)
GAPDHGlyceraldehyde-3-phosphate dehydrogenase. (359 aa)
PFKFB16-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1. (478 aa)
ACO2Aconitase 2. (628 aa)
PDHBPyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. (393 aa)
GCKPhosphotransferase. (400 aa)
SDHCSuccinate dehydrogenase complex subunit C. (168 aa)
PGK1Phosphoglycerate kinase. (389 aa)
TKTL2Transketolase like 2. (485 aa)
PFKPATP-dependent 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily. (784 aa)
PGD6-phosphogluconate dehydrogenase, decarboxylating; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH. (483 aa)
SUCLG2Succinate--CoA ligase [GDP-forming] subunit beta, mitochondrial; GTP-specific succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (384 aa)
DBTDihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex. (492 aa)
FBXL5F-box and leucine rich repeat protein 5. (705 aa)
LOC102350445Malate synthase-like. (539 aa)
GOT1Aspartate aminotransferase. (399 aa)
H3B2X1_LATCHUncharacterized protein. (738 aa)
BPGMPhosphoglycerate mutase; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily. (259 aa)
IDH1Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (414 aa)
H6PDHexose-6-phosphate dehydrogenase/glucose 1-dehydrogenase. (793 aa)
ENO3Enolase 3. (434 aa)
PGAM2Phosphoglycerate mutase; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily. (254 aa)
DLATAcetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (629 aa)
NAGSN-acetylglutamate synthase. (508 aa)
ENO1Enolase 1. (438 aa)
LOC102363309L-lactate dehydrogenase; Belongs to the LDH/MDH superfamily. (333 aa)
SDHDSuccinate dehydrogenase [ubiquinone] cytochrome b small subunit; Membrane-anchoring subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q); Belongs to the CybS family. (156 aa)
SDHBSuccinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial; Iron-sulfur protein (IP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). (285 aa)
DHTKD1Dehydrogenase E1 and transketolase domain containing 1. (931 aa)
TALDO1Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway. (337 aa)
MDH1Malate dehydrogenase. (335 aa)
H3BAN4_LATCHOxoglutarate (alpha-ketoglutarate) dehydrogenase b (lipoamide). (773 aa)
H3BB55_LATCHPhosphoglycerate mutase; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily. (245 aa)
HK2Hexokinase 2. (918 aa)
LOC102349397Uncharacterized protein. (574 aa)
PFKFB36-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3. (509 aa)
LOC102354033ADP-dependent glucokinase 2. (441 aa)
PCK1Phosphoenolpyruvate carboxykinase 1. (622 aa)
IDH2Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (402 aa)
TIGARTP53 induced glycolysis regulatory phosphatase. (212 aa)
BCKDHA2-oxoisovalerate dehydrogenase subunit alpha; The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3). (446 aa)
MDH2Malate dehydrogenase. (337 aa)
PCPyruvate carboxylase. (722 aa)
PFKFB26-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2. (494 aa)
DLSTDihydrolipoamide S-succinyltransferase. (458 aa)
CSCitrate synthase; Belongs to the citrate synthase family. (468 aa)
PFKMPhosphofructokinase, muscle. (830 aa)
G6PCGlucose-6-phosphatase; Belongs to the glucose-6-phosphatase family. (357 aa)
TKTTransketolase. (626 aa)
IDH3BIsocitrate dehydrogenase [NAD] subunit, mitochondrial. (363 aa)
MYCBPAPMYCBP associated protein. (869 aa)
ALDOBFructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family. (364 aa)
G6PDGlucose-6-phosphate 1-dehydrogenase; Catalyzes the rate-limiting step of the oxidative pentose- phosphate pathway, which represents a route for the dissimilation of carbohydrates besides glycolysis. (430 aa)
G6PC2Glucose-6-phosphatase; Belongs to the glucose-6-phosphatase family. (355 aa)
PKLRPyruvate kinase; Belongs to the pyruvate kinase family. (530 aa)
GOT1L1Glutamic-oxaloacetic transaminase 1 like 1. (405 aa)
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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