STRINGSTRING
LOC102361787 LOC102361787 ACO1 ACO1 IREB2 IREB2 GOT2 GOT2 BCKDHB BCKDHB H2ZXP4_LATCH H2ZXP4_LATCH URB2 URB2 DLD DLD ACLY ACLY SUCLG1 SUCLG1 IDH3A IDH3A SDHA SDHA IDH3G IDH3G FH FH LOC102362883 LOC102362883 H3AIU3_LATCH H3AIU3_LATCH H3AK14_LATCH H3AK14_LATCH SUCLA2 SUCLA2 L2HGDH L2HGDH DDO DDO ME2 ME2 PDHX PDHX LDHA LDHA OGDHL OGDHL H3AQW3_LATCH H3AQW3_LATCH PDHA1 PDHA1 ACO2 ACO2 PDHB PDHB SDHC SDHC SUCLG2 SUCLG2 DBT DBT FBXL5 FBXL5 LOC102350445 LOC102350445 GOT1 GOT1 IDH1 IDH1 DLAT DLAT NAGS NAGS SDHD SDHD SDHB SDHB DHTKD1 DHTKD1 MDH1 MDH1 H3BAN4_LATCH H3BAN4_LATCH IDH2 IDH2 BCKDHA BCKDHA MDH2 MDH2 DLST DLST CS CS IDH3B IDH3B GOT1L1 GOT1L1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LOC102361787Aminotran_1_2 domain-containing protein. (285 aa)
ACO1Aconitase 1. (673 aa)
IREB2Iron responsive element binding protein 2. (965 aa)
GOT2Aspartate aminotransferase. (392 aa)
BCKDHBBranched chain keto acid dehydrogenase E1 subunit beta. (217 aa)
H2ZXP4_LATCHUncharacterized protein. (727 aa)
URB2URB2 ribosome biogenesis homolog. (1538 aa)
DLDDihydrolipoamide dehydrogenase. (236 aa)
ACLYATP citrate lyase. (978 aa)
SUCLG1Succinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and specificity for either ATP or GTP is provided by different beta subunits. (335 aa)
IDH3AIsocitrate dehydrogenase [NAD] subunit, mitochondrial. (366 aa)
SDHASuccinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial; Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). (670 aa)
IDH3GIsocitrate dehydrogenase [NAD] subunit, mitochondrial. (400 aa)
FHFumarate hydratase. (491 aa)
LOC102362883Iso_dh domain-containing protein. (384 aa)
H3AIU3_LATCHDihydrolipoamide dehydrogenase. (233 aa)
H3AK14_LATCHUncharacterized protein. (177 aa)
SUCLA2Succinate-CoA ligase ADP-forming beta subunit. (374 aa)
L2HGDHL-2-hydroxyglutarate dehydrogenase. (419 aa)
DDOD-aspartate oxidase. (338 aa)
ME2Malic enzyme. (543 aa)
PDHXDihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex. (534 aa)
LDHAL-lactate dehydrogenase. (362 aa)
OGDHLOxoglutarate dehydrogenase like. (1017 aa)
H3AQW3_LATCHZgc:113208. (209 aa)
PDHA1Pyruvate dehydrogenase E1 component subunit alpha; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (400 aa)
ACO2Aconitase 2. (628 aa)
PDHBPyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. (393 aa)
SDHCSuccinate dehydrogenase complex subunit C. (168 aa)
SUCLG2Succinate--CoA ligase [GDP-forming] subunit beta, mitochondrial; GTP-specific succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (384 aa)
DBTDihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex. (492 aa)
FBXL5F-box and leucine rich repeat protein 5. (705 aa)
LOC102350445Malate synthase-like. (539 aa)
GOT1Aspartate aminotransferase. (399 aa)
IDH1Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (414 aa)
DLATAcetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (629 aa)
NAGSN-acetylglutamate synthase. (508 aa)
SDHDSuccinate dehydrogenase [ubiquinone] cytochrome b small subunit; Membrane-anchoring subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q); Belongs to the CybS family. (156 aa)
SDHBSuccinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial; Iron-sulfur protein (IP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). (285 aa)
DHTKD1Dehydrogenase E1 and transketolase domain containing 1. (931 aa)
MDH1Malate dehydrogenase. (335 aa)
H3BAN4_LATCHOxoglutarate (alpha-ketoglutarate) dehydrogenase b (lipoamide). (773 aa)
IDH2Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (402 aa)
BCKDHA2-oxoisovalerate dehydrogenase subunit alpha; The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3). (446 aa)
MDH2Malate dehydrogenase. (337 aa)
DLSTDihydrolipoamide S-succinyltransferase. (458 aa)
CSCitrate synthase; Belongs to the citrate synthase family. (468 aa)
IDH3BIsocitrate dehydrogenase [NAD] subunit, mitochondrial. (363 aa)
GOT1L1Glutamic-oxaloacetic transaminase 1 like 1. (405 aa)
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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