node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AMT | GCSH | ENSLACP00000017424 | ENSLACP00000006340 | Aminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine; Belongs to the GcvT family. | Glycine cleavage system H protein; The H protein shuttles the methylamine group of glycine from the P protein to the T protein; Belongs to the GcvH family. | 0.999 |
AMT | GLDC | ENSLACP00000017424 | ENSLACP00000010100 | Aminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine; Belongs to the GcvT family. | Glycine cleavage system P protein; The glycine cleavage system catalyzes the degradation of glycine. | 0.999 |
AMT | MTHFR | ENSLACP00000017424 | ENSLACP00000010131 | Aminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine; Belongs to the GcvT family. | Methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. | 0.979 |
AMT | MTR | ENSLACP00000017424 | ENSLACP00000018670 | Aminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine; Belongs to the GcvT family. | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.950 |
AMT | SHMT2 | ENSLACP00000017424 | ENSLACP00000021709 | Aminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine; Belongs to the GcvT family. | Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. | 0.990 |
GCSH | AMT | ENSLACP00000006340 | ENSLACP00000017424 | Glycine cleavage system H protein; The H protein shuttles the methylamine group of glycine from the P protein to the T protein; Belongs to the GcvH family. | Aminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine; Belongs to the GcvT family. | 0.999 |
GCSH | GLDC | ENSLACP00000006340 | ENSLACP00000010100 | Glycine cleavage system H protein; The H protein shuttles the methylamine group of glycine from the P protein to the T protein; Belongs to the GcvH family. | Glycine cleavage system P protein; The glycine cleavage system catalyzes the degradation of glycine. | 0.999 |
GCSH | MTHFR | ENSLACP00000006340 | ENSLACP00000010131 | Glycine cleavage system H protein; The H protein shuttles the methylamine group of glycine from the P protein to the T protein; Belongs to the GcvH family. | Methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. | 0.972 |
GCSH | MTR | ENSLACP00000006340 | ENSLACP00000018670 | Glycine cleavage system H protein; The H protein shuttles the methylamine group of glycine from the P protein to the T protein; Belongs to the GcvH family. | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.760 |
GCSH | SHMT2 | ENSLACP00000006340 | ENSLACP00000021709 | Glycine cleavage system H protein; The H protein shuttles the methylamine group of glycine from the P protein to the T protein; Belongs to the GcvH family. | Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. | 0.997 |
GLDC | AMT | ENSLACP00000010100 | ENSLACP00000017424 | Glycine cleavage system P protein; The glycine cleavage system catalyzes the degradation of glycine. | Aminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine; Belongs to the GcvT family. | 0.999 |
GLDC | GCSH | ENSLACP00000010100 | ENSLACP00000006340 | Glycine cleavage system P protein; The glycine cleavage system catalyzes the degradation of glycine. | Glycine cleavage system H protein; The H protein shuttles the methylamine group of glycine from the P protein to the T protein; Belongs to the GcvH family. | 0.999 |
GLDC | MTHFR | ENSLACP00000010100 | ENSLACP00000010131 | Glycine cleavage system P protein; The glycine cleavage system catalyzes the degradation of glycine. | Methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. | 0.970 |
GLDC | MTR | ENSLACP00000010100 | ENSLACP00000018670 | Glycine cleavage system P protein; The glycine cleavage system catalyzes the degradation of glycine. | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.819 |
GLDC | SHMT2 | ENSLACP00000010100 | ENSLACP00000021709 | Glycine cleavage system P protein; The glycine cleavage system catalyzes the degradation of glycine. | Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. | 0.998 |
MTHFR | AMT | ENSLACP00000010131 | ENSLACP00000017424 | Methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. | Aminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine; Belongs to the GcvT family. | 0.979 |
MTHFR | GCSH | ENSLACP00000010131 | ENSLACP00000006340 | Methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. | Glycine cleavage system H protein; The H protein shuttles the methylamine group of glycine from the P protein to the T protein; Belongs to the GcvH family. | 0.972 |
MTHFR | GLDC | ENSLACP00000010131 | ENSLACP00000010100 | Methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. | Glycine cleavage system P protein; The glycine cleavage system catalyzes the degradation of glycine. | 0.970 |
MTHFR | MTR | ENSLACP00000010131 | ENSLACP00000018670 | Methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.995 |
MTHFR | SHMT2 | ENSLACP00000010131 | ENSLACP00000021709 | Methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. | Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. | 0.995 |