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| | UBE2D2 | Ubiquitin conjugating enzyme E2 D2; Belongs to the ubiquitin-conjugating enzyme family. (146 aa) |
| | H2ZRM4_LATCH | Uncharacterized protein. (379 aa) |
| | H2ZRS3_LATCH | Uncharacterized protein. (312 aa) |
| | PSMC4 | Proteasome 26S subunit, ATPase 4; Belongs to the AAA ATPase family. (316 aa) |
| | POMP | Proteasome maturation protein. (142 aa) |
| | PSMB1 | Proteasome subunit beta. (203 aa) |
| | PSMD1 | 26S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family. (730 aa) |
| | SENP7 | SUMO specific peptidase 7. (705 aa) |
| | PSMA4 | Proteasome subunit alpha type. (272 aa) |
| | PSME2 | Proteasome activator subunit 2. (241 aa) |
| | UBR1 | E3 ubiquitin-protein ligase; Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N- terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation. (1724 aa) |
| | PSMB6 | Proteasome subunit beta. (245 aa) |
| | H2ZVF8_LATCH | Uncharacterized protein. (313 aa) |
| | UBQLN1 | Ubiquilin 1. (526 aa) |
| | LOC102366904 | UBIQUITIN_CONJUGAT_2 domain-containing protein. (208 aa) |
| | PSME4 | Proteasome activator subunit 4. (1848 aa) |
| | PSMD6 | Proteasome 26S subunit, non-ATPase 6. (389 aa) |
| | UBA1 | Ubiquitin-like modifier activating enzyme 1; Belongs to the ubiquitin-activating E1 family. (1059 aa) |
| | UBE2V2 | Ubiquitin conjugating enzyme E2 V2. (55 aa) |
| | PSME3 | Proteasome activator subunit 3. (257 aa) |
| | UBE4B | Ubiquitination factor E4B. (1348 aa) |
| | PSMC2 | Proteasome 26S subunit, ATPase 2; Belongs to the AAA ATPase family. (445 aa) |
| | RNF169 | Ring finger protein 169. (684 aa) |
| | PSME1 | Proteasome activator subunit 1. (252 aa) |
| | TNKS2 | Poly [ADP-ribose] polymerase. (1174 aa) |
| | LOC102346166 | Ubiquitin-like domain-containing protein. (95 aa) |
| | UBFD1 | Ubiquitin family domain containing 1. (281 aa) |
| | WAC | WW domain containing adaptor with coiled-coil. (643 aa) |
| | PAAF1 | Proteasomal ATPase associated factor 1. (382 aa) |
| | UBE2L6 | UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (144 aa) |
| | LOC102350907 | Ubiquitin A-52 residue ribosomal protein fusion product 1. (128 aa) |
| | LONRF2 | LON peptidase N-terminal domain and ring finger 2. (777 aa) |
| | LOC102360626 | HECT domain-containing protein. (629 aa) |
| | UBE2E1 | Ubiquitin conjugating enzyme E2 E1; Belongs to the ubiquitin-conjugating enzyme family. (193 aa) |
| | PSMB4 | Proteasome subunit beta; Belongs to the peptidase T1B family. (274 aa) |
| | H3A4V8_LATCH | Proteasome subunit beta. (260 aa) |
| | PSMD14 | Proteasome 26S subunit, non-ATPase 14. (314 aa) |
| | H3A5F1_LATCH | UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (153 aa) |
| | TOP2B | DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks. (1615 aa) |
| | RNF20 | E3 ubiquitin protein ligase. (1004 aa) |
| | PSMA7 | Proteasome subunit alpha type. (251 aa) |
| | PSMB3 | Proteasome subunit beta 3. (159 aa) |
| | MPND | MPN domain containing. (479 aa) |
| | PSMG2 | Proteasome assembly chaperone 2. (205 aa) |
| | UBE2D1 | Ubiquitin conjugating enzyme E2 D1; Belongs to the ubiquitin-conjugating enzyme family. (147 aa) |
| | SUMO3 | Small ubiquitin-related modifier. (96 aa) |
| | KCMF1 | Potassium channel modulatory factor 1. (384 aa) |
| | LOC102365523 | Uncharacterized protein; Belongs to the peptidase C19 family. (930 aa) |
| | OTUB2 | Ubiquitin thioesterase. (270 aa) |
| | CDC34 | Cell division cycle 34 homolog (S. cerevisiae) a; Belongs to the ubiquitin-conjugating enzyme family. (241 aa) |
| | RNF8 | E3 ubiquitin-protein ligase RNF8; E3 ubiquitin-protein ligase that plays a key role in DNA damage signaling via 2 distinct roles: by mediating the 'Lys-63'-linked ubiquitination of histones H2A and H2AX and promoting the recruitment of DNA repair proteins at double-strand breaks (DSBs) sites, and by catalyzing 'Lys-48'-linked ubiquitination to remove target proteins from DNA damage sites. Following DNA DSBs, it is recruited to the sites of damage by ATM-phosphorylated MDC1 and catalyzes the 'Lys-63'-linked ubiquitination of histones H2A and H2AX, thereby promoting the formation of TP53 [...] (542 aa) |
| | PSMD13 | Proteasome 26S subunit, non-ATPase 13. (378 aa) |
| | UBLCP1 | Ubiquitin like domain containing CTD phosphatase 1. (321 aa) |
| | UBA2 | SUMO-activating enzyme subunit 2; The heterodimer acts as an E1 ligase for SUMO1, SUMO2, SUMO3, and probably SUMO4. It mediates ATP-dependent activation of SUMO proteins followed by formation of a thioester bond between a SUMO protein and a conserved active site cysteine residue on UBA2/SAE2. Belongs to the ubiquitin-activating E1 family. (635 aa) |
| | UCHL5 | Ubiquitin carboxyl-terminal hydrolase. (329 aa) |
| | UBE2N | Ubiquitin-conjugating enzyme E2Na; Belongs to the ubiquitin-conjugating enzyme family. (159 aa) |
| | NFATC2IP | Ubiquitin-like domain-containing protein. (258 aa) |
| | KCTD2 | Potassium channel tetramerization domain containing 2. (265 aa) |
| | RNF146 | Ring finger protein 146. (347 aa) |
| | H3AFK9_LATCH | RING-type domain-containing protein. (482 aa) |
| | RPS27A | Ribosomal protein S27a. (156 aa) |
| | LOC102347040 | Ubiquitin-conjugating enzyme E2Ia; Belongs to the ubiquitin-conjugating enzyme family. (158 aa) |
| | HECTD1 | HECT domain E3 ubiquitin protein ligase 1. (2580 aa) |
| | PSMD2 | 26S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family. (899 aa) |
| | HACE1 | HECT domain and ankyrin repeat containing E3 ubiquitin protein ligase 1. (916 aa) |
| | H3AHP8_LATCH | TOPEUc domain-containing protein. (764 aa) |
| | TNKS | Poly [ADP-ribose] polymerase. (1233 aa) |
| | KXD1 | Ubiquitin-like domain-containing protein. (231 aa) |
| | ZFAND4 | Zinc finger AN1-type containing 4. (738 aa) |
| | UBE2R2 | Ubiquitin conjugating enzyme E2 R2; Belongs to the ubiquitin-conjugating enzyme family. (238 aa) |
| | PSMF1 | Proteasome inhibitor subunit 1. (265 aa) |
| | TRAF7 | TNF receptor associated factor 7. (671 aa) |
| | UBE2E2 | UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (137 aa) |
| | ADRM1 | Adhesion regulating molecule 1. (438 aa) |
| | TOP2A | DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks. (1569 aa) |
| | TRIP12 | Thyroid hormone receptor interactor 12. (2023 aa) |
| | LOC102361436 | Uncharacterized protein. (116 aa) |
| | TRAF4 | TNF receptor-associated factor. (434 aa) |
| | PSMG3 | Proteasome assembly chaperone 3. (122 aa) |
| | UBE2J1 | Ubiquitin conjugating enzyme E2 J1. (321 aa) |
| | UBE2A | Ubiquitin conjugating enzyme E2 A; Belongs to the ubiquitin-conjugating enzyme family. (152 aa) |
| | HTRA1 | HtrA serine peptidase 1. (477 aa) |
| | PSMD11 | Proteasome 26S subunit, non-ATPase 11. (422 aa) |
| | RNF40 | E3 ubiquitin protein ligase. (838 aa) |
| | UBQLN4 | Ubiquilin 4. (636 aa) |
| | UBE2W | Ubiquitin-conjugating enzyme E2W (putative). (157 aa) |
| | PSMC5 | Proteasome 26S subunit, ATPase 5; Belongs to the AAA ATPase family. (406 aa) |
| | HTRA3 | HtrA serine peptidase 3. (460 aa) |
| | H3AR23_LATCH | PDZ domain-containing protein. (98 aa) |
| | AUP1 | AUP1 lipid droplet regulating VLDL assembly factor. (423 aa) |
| | PSMD7 | Proteasome 26S subunit, non-ATPase 7. (322 aa) |
| | GCDH | Glutaryl-CoA dehydrogenase. (437 aa) |
| | UBA7 | Uncharacterized protein; Belongs to the ubiquitin-activating E1 family. (915 aa) |
| | PIAS4 | Protein inhibitor of activated STAT 4. (370 aa) |
| | MARCHF6 | Membrane associated ring-CH-type finger 6. (775 aa) |
| | SENP6 | SUMO specific peptidase 6. (1078 aa) |
| | PSMG4 | Uncharacterized protein. (122 aa) |
| | PSMA8 | Proteasome subunit alpha type. (251 aa) |
| | UBE2H | Ubiquitin conjugating enzyme E2 H; Belongs to the ubiquitin-conjugating enzyme family. (185 aa) |
| | UBR2 | E3 ubiquitin-protein ligase; Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N- terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation. (1767 aa) |
| | LOC102355775 | DUF862 domain-containing protein. (196 aa) |
| | PSMD12 | Proteasome 26S subunit, non-ATPase 12. (455 aa) |
| | UBR5 | Ubiquitin protein ligase E3 component n-recognin 5. (2787 aa) |
| | PSMA1 | Proteasome subunit alpha type. (269 aa) |
| | LOC102363126 | Small ubiquitin-related modifier. (110 aa) |
| | PSMD10 | Proteasome 26S subunit, non-ATPase 10. (234 aa) |
| | UBE3C | Ubiquitin protein ligase E3C. (1036 aa) |
| | UBE2V2-2 | Ubiquitin-conjugating enzyme E2 variant 2. (102 aa) |
| | PSMA2 | Proteasome subunit alpha type. (234 aa) |
| | BBIP1 | Uncharacterized protein. (499 aa) |
| | SENP2 | ULP_PROTEASE domain-containing protein. (248 aa) |
| | UBE2K | Ubiquitin conjugating enzyme E2 K; Belongs to the ubiquitin-conjugating enzyme family. (211 aa) |
| | PSMB10 | Proteasome subunit beta. (278 aa) |
| | UBA6 | Ubiquitin like modifier activating enzyme 6. (1027 aa) |
| | PSMB8 | Proteasome subunit beta. (271 aa) |
| | UBE3A | Ubiquitin-protein ligase E3A; E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and transfers it to its substrates. (907 aa) |
| | PSMC1 | Proteasome 26S subunit, ATPase 1; Belongs to the AAA ATPase family. (451 aa) |
| | LOC102350007 | Small ubiquitin-related modifier. (100 aa) |
| | PSMB9 | Proteasome subunit beta. (219 aa) |
| | UBE2G2 | Ubiquitin conjugating enzyme E2 G2; Belongs to the ubiquitin-conjugating enzyme family. (168 aa) |
| | H3B381_LATCH | Uncharacterized protein. (767 aa) |
| | PSMD5 | Proteasome 26S subunit, non-ATPase 5. (501 aa) |
| | H3B3C1_LATCH | Uncharacterized protein. (130 aa) |
| | TDP1 | Tyrosyl-DNA phosphodiesterase 1. (614 aa) |
| | KIAA2012 | Uncharacterized protein. (695 aa) |
| | USP14 | Ubiquitin carboxyl-terminal hydrolase. (490 aa) |
| | PSMD3 | Proteasome 26S subunit, non-ATPase 3. (524 aa) |
| | UBE2Q1 | Ubiquitin conjugating enzyme E2 Q1. (370 aa) |
| | PSMB11 | Proteasome subunit beta. (269 aa) |
| | LOC102358862 | Proteasome subunit beta. (272 aa) |
| | LOC102350961 | Proteasome subunit beta. (260 aa) |
| | PRPF38B | Uncharacterized protein. (540 aa) |
| | PSMD8 | Proteasome 26S subunit, non-ATPase 8. (309 aa) |
| | ZMIZ2 | Zinc finger MIZ-type containing 2. (921 aa) |
| | PSMA5 | Proteasome subunit alpha type. (244 aa) |
| | SAE1 | SUMO1 activating enzyme subunit 1. (344 aa) |
| | LOC102365742 | Ubiquitin-conjugating enzyme E2G 1b (UBC7 homolog, yeast); Belongs to the ubiquitin-conjugating enzyme family. (169 aa) |
| | ECPAS | Ecm29 proteasome adaptor and scaffold. (1848 aa) |
| | PIAS1 | Protein inhibitor of activated STAT 1. (644 aa) |
| | PSMB2 | Proteasome subunit beta. (199 aa) |
| | UBE2B | Ubiquitin conjugating enzyme E2 B; Belongs to the ubiquitin-conjugating enzyme family. (152 aa) |
| | H3B969_LATCH | Uncharacterized protein. (643 aa) |
| | UBE2Z | Ubiquitin conjugating enzyme E2 Z. (379 aa) |
| | TARDBP | TAR DNA binding protein. (412 aa) |
| | CSKMT | Citrate synthase lysine methyltransferase. (257 aa) |
| | PIAS3 | Protein inhibitor of activated STAT 3. (645 aa) |
| | CEP112 | Centrosomal protein 112. (952 aa) |
| | SENP5 | SUMO specific peptidase 5. (764 aa) |
| | PSMA6 | Proteasome subunit alpha type. (289 aa) |
| | UBE2V1 | UBIQUITIN_CONJUGAT_2 domain-containing protein. (153 aa) |
| | LOC102350135 | IF rod domain-containing protein; Belongs to the intermediate filament family. (356 aa) |
| | RNF217 | RBR-type E3 ubiquitin transferase. (177 aa) |
| | TOP1 | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus r [...] (743 aa) |
| | LOC102365446 | Proteasome subunit alpha type. (246 aa) |
| | PSMD9 | Proteasome 26S subunit, non-ATPase 9. (210 aa) |
| | H3BGV7_LATCH | LON peptidase N-terminal domain and ring finger 1. (589 aa) |
| | C1QTNF12 | C1q and TNF related 12. (265 aa) |
| | PSMB7 | Proteasome subunit beta 7. (289 aa) |
| | PSMA3 | Proteasome subunit alpha type. (259 aa) |
| | PSMC3 | Proteasome 26S subunit, ATPase 3. (192 aa) |
| | PSMC6 | Proteasome 26S subunit, ATPase 6; Belongs to the AAA ATPase family. (389 aa) |
| | MIB2 | Mindbomb E3 ubiquitin protein ligase 2. (942 aa) |
| | UBR4 | Ubiquitin protein ligase E3 component n-recognin 4. (5179 aa) |
| | LOC102349804 | Proteasome subunit alpha type. (274 aa) |
| | UBE2G1 | Ubiquitin conjugating enzyme E2 G1; Belongs to the ubiquitin-conjugating enzyme family. (170 aa) |
| | PIAS2 | Protein inhibitor of activated STAT 2. (564 aa) |
| | LOC102347893 | UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (152 aa) |
| | M3XHZ0_LATCH | UBIQUITIN_CONJUGAT_2 domain-containing protein. (346 aa) |
| | UBD | Uncharacterized protein. (163 aa) |
| | LOC102365863 | UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (158 aa) |
| | DESI1 | Desumoylating isopeptidase 1. (104 aa) |
| | DESI2 | Desumoylating isopeptidase 2. (194 aa) |
| | LOC102362445 | PCI domain-containing protein. (376 aa) |
| | UBE2D3 | Ubiquitin conjugating enzyme E2 D3; Belongs to the ubiquitin-conjugating enzyme family. (118 aa) |
| | M3XLP3_LATCH | Uncharacterized protein. (408 aa) |
| | UBE2U | Ubiquitin conjugating enzyme E2 U; Belongs to the ubiquitin-conjugating enzyme family. (337 aa) |
