(31 nodes) Mixed, incl. Arginine biosynthesis, and Gamma-aminobutyric acid metabolic process network (Latimeria chalumnae)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	TMEM109	Uncharacterized protein. (257 aa)
	GLUL	Glutamine synthetase. (408 aa)
	LOC102358398	CN hydrolase domain-containing protein. (451 aa)
	LGSN	Lengsin, lens protein with glutamine synthetase domain; Belongs to the glutamine synthetase family. (451 aa)
	ALDH5A1	Succinate-semialdehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (511 aa)
	LOC102358421	Uncharacterized protein. (548 aa)
	AASS	Aminoadipate-semialdehyde synthase. (935 aa)
	ABAT	4-aminobutyrate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (490 aa)
	GLUD1	Glutamate dehydrogenase 1b; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (541 aa)
	CPS1	Carbamoyl-phosphate synthase 1. (1332 aa)
	ACY1	Aminoacylase 1. (428 aa)
	AADACL4	Arylacetamide deacetylase-like 4. (421 aa)
	ALDH18A1	Delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family. (796 aa)
	FDXR	NADPH:adrenodoxin oxidoreductase, mitochondrial. (485 aa)
	CAD	Carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase. (2203 aa)
	GAD1	Glutamate decarboxylase 1. (590 aa)
	ASNSD1	Asparagine synthetase domain containing 1. (642 aa)
	FAAH2	Fatty acid amide hydrolase 2. (534 aa)
	PHYKPL	5-phosphohydroxy-L-lysine phospho-lyase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (462 aa)
	OTC	Ornithine carbamoyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. (354 aa)
	LOC102361837	Glutamine synthetase. (370 aa)
	OAT	Ornithine aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (443 aa)
	GLS	Glutaminase. (577 aa)
	CNDP2	Carnosine dipeptidase 2. (474 aa)
	LOC102355447	Zgc:114181. (490 aa)
	ASS1	Argininosuccinate synthase 1. (441 aa)
	ARG2	Arginase. (363 aa)
	HDC	Histidine decarboxylase. (666 aa)
	GLS2	Glutaminase 2. (601 aa)
	IAH1	Isoamyl acetate hydrolyzing esterase 1 (putative). (164 aa)
	ERICH2	Glutamate rich 2. (143 aa)

Your Current Organism:

Latimeria chalumnae

NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AADACL4	ABAT	ENSLACP00000011292	ENSLACP00000006938	Arylacetamide deacetylase-like 4.	4-aminobutyrate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.	0.709
AADACL4	ALDH5A1	ENSLACP00000011292	ENSLACP00000004782	Arylacetamide deacetylase-like 4.	Succinate-semialdehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.	0.702
AASS	ALDH18A1	ENSLACP00000006766	ENSLACP00000012633	Aminoadipate-semialdehyde synthase.	Delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family.	0.704
AASS	ASS1	ENSLACP00000006766	ENSLACP00000020235	Aminoadipate-semialdehyde synthase.	Argininosuccinate synthase 1.	0.720
AASS	GLS	ENSLACP00000006766	ENSLACP00000018602	Aminoadipate-semialdehyde synthase.	Glutaminase.	0.511
AASS	GLS2	ENSLACP00000006766	ENSLACP00000021640	Aminoadipate-semialdehyde synthase.	Glutaminase 2.	0.511
AASS	GLUD1	ENSLACP00000006766	ENSLACP00000007586	Aminoadipate-semialdehyde synthase.	Glutamate dehydrogenase 1b; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.	0.617
AASS	LOC102358398	ENSLACP00000006766	ENSLACP00000001881	Aminoadipate-semialdehyde synthase.	CN hydrolase domain-containing protein.	0.821
AASS	OAT	ENSLACP00000006766	ENSLACP00000017508	Aminoadipate-semialdehyde synthase.	Ornithine aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.	0.735
AASS	OTC	ENSLACP00000006766	ENSLACP00000017385	Aminoadipate-semialdehyde synthase.	Ornithine carbamoyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily.	0.493
AASS	PHYKPL	ENSLACP00000006766	ENSLACP00000017347	Aminoadipate-semialdehyde synthase.	5-phosphohydroxy-L-lysine phospho-lyase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.	0.933
ABAT	AADACL4	ENSLACP00000006938	ENSLACP00000011292	4-aminobutyrate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.	Arylacetamide deacetylase-like 4.	0.709
ABAT	ACY1	ENSLACP00000006938	ENSLACP00000009876	4-aminobutyrate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.	Aminoacylase 1.	0.401
ABAT	ALDH18A1	ENSLACP00000006938	ENSLACP00000012633	4-aminobutyrate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.	Delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family.	0.631
ABAT	ALDH5A1	ENSLACP00000006938	ENSLACP00000004782	4-aminobutyrate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.	Succinate-semialdehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.	0.987
ABAT	ARG2	ENSLACP00000006938	ENSLACP00000020265	4-aminobutyrate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.	Arginase.	0.566
ABAT	ASNSD1	ENSLACP00000006938	ENSLACP00000015491	4-aminobutyrate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.	Asparagine synthetase domain containing 1.	0.575
ABAT	ASS1	ENSLACP00000006938	ENSLACP00000020235	4-aminobutyrate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.	Argininosuccinate synthase 1.	0.481
ABAT	CNDP2	ENSLACP00000006938	ENSLACP00000019548	4-aminobutyrate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.	Carnosine dipeptidase 2.	0.936
ABAT	ERICH2	ENSLACP00000006938	ENSLACP00000023210	4-aminobutyrate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.	Glutamate rich 2.	0.493