(10 nodes) Hrd1p ubiquitin ligase ERAD-L complex, and Protein OS-9-like network (Latimeria chalumnae)

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second shell of interactors

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Your Input:
	ERLEC1	Endoplasmic reticulum lectin 1. (486 aa)
	DERL1	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family. (254 aa)
	DERL3	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family. (203 aa)
	SEL1L3	SEL1L family member 3. (1031 aa)
	AMFR	Autocrine motility factor receptor. (653 aa)
	SEL1L	SEL1L adaptor subunit of ERAD E3 ubiquitin ligase. (759 aa)
	SEL1L2	SEL1L2 adaptor subunit of ERAD E3 ligase. (589 aa)
	DERL2	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family. (239 aa)
	OS9	OS9 endoplasmic reticulum lectin. (662 aa)
	H3BG62_LATCH	RING-type domain-containing protein. (587 aa)

Your Current Organism:

Latimeria chalumnae

NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AMFR	DERL1	ENSLACP00000017165	ENSLACP00000008715	Autocrine motility factor receptor.	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	0.974
AMFR	DERL2	ENSLACP00000017165	ENSLACP00000020713	Autocrine motility factor receptor.	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	0.930
AMFR	DERL3	ENSLACP00000017165	ENSLACP00000011180	Autocrine motility factor receptor.	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	0.930
AMFR	ERLEC1	ENSLACP00000017165	ENSLACP00000007837	Autocrine motility factor receptor.	Endoplasmic reticulum lectin 1.	0.929
AMFR	OS9	ENSLACP00000017165	ENSLACP00000020725	Autocrine motility factor receptor.	OS9 endoplasmic reticulum lectin.	0.929
AMFR	SEL1L	ENSLACP00000017165	ENSLACP00000017433	Autocrine motility factor receptor.	SEL1L adaptor subunit of ERAD E3 ubiquitin ligase.	0.897
AMFR	SEL1L2	ENSLACP00000017165	ENSLACP00000018921	Autocrine motility factor receptor.	SEL1L2 adaptor subunit of ERAD E3 ligase.	0.883
AMFR	SEL1L3	ENSLACP00000017165	ENSLACP00000013351	Autocrine motility factor receptor.	SEL1L family member 3.	0.864
DERL1	AMFR	ENSLACP00000008715	ENSLACP00000017165	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	Autocrine motility factor receptor.	0.974
DERL1	DERL2	ENSLACP00000008715	ENSLACP00000020713	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	0.990
DERL1	DERL3	ENSLACP00000008715	ENSLACP00000011180	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	0.912
DERL1	ERLEC1	ENSLACP00000008715	ENSLACP00000007837	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	Endoplasmic reticulum lectin 1.	0.971
DERL1	H3BG62_LATCH	ENSLACP00000008715	ENSLACP00000020883	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	RING-type domain-containing protein.	0.974
DERL1	OS9	ENSLACP00000008715	ENSLACP00000020725	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	OS9 endoplasmic reticulum lectin.	0.971
DERL1	SEL1L	ENSLACP00000008715	ENSLACP00000017433	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	SEL1L adaptor subunit of ERAD E3 ubiquitin ligase.	0.978
DERL1	SEL1L2	ENSLACP00000008715	ENSLACP00000018921	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	SEL1L2 adaptor subunit of ERAD E3 ligase.	0.962
DERL1	SEL1L3	ENSLACP00000008715	ENSLACP00000013351	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	SEL1L family member 3.	0.952
DERL2	AMFR	ENSLACP00000020713	ENSLACP00000017165	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	Autocrine motility factor receptor.	0.930
DERL2	DERL1	ENSLACP00000020713	ENSLACP00000008715	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	0.990
DERL2	ERLEC1	ENSLACP00000020713	ENSLACP00000007837	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	Endoplasmic reticulum lectin 1.	0.937