STRINGSTRING
DEPDC1 DEPDC1 CHEK2 CHEK2 WEE1 WEE1 H2ZSE1_LATCH H2ZSE1_LATCH TRIP13 TRIP13 CDC16 CDC16 ASPM ASPM LOC102345107 LOC102345107 LOC102352831 LOC102352831 BUB3 BUB3 H2ZV04_LATCH H2ZV04_LATCH CCNA2 CCNA2 LOC102356560 LOC102356560 LOC102367471 LOC102367471 CCNE2 CCNE2 H2ZXS9_LATCH H2ZXS9_LATCH CCNE1 CCNE1 LOC102355137 LOC102355137 H2ZZ70_LATCH H2ZZ70_LATCH CCNB2 CCNB2 CDK18 CDK18 H3A169_LATCH H3A169_LATCH CCNG2 CCNG2 CUL1 CUL1 LOC102365114 LOC102365114 FZR1 FZR1 PLK3 PLK3 H3A3C5_LATCH H3A3C5_LATCH LOC102349711 LOC102349711 CDK6 CDK6 PLK1 PLK1 CCNI CCNI PLK5 PLK5 MAD2L1BP MAD2L1BP H3A6M6_LATCH H3A6M6_LATCH ANAPC11 ANAPC11 RBX1 RBX1 CDK14 CDK14 CDK4 CDK4 CDC20 CDC20 ZWILCH ZWILCH CDKN2C CDKN2C CCNJ CCNJ CDC25B CDC25B UBE2S UBE2S KIF2C KIF2C CCNB1 CCNB1 CDCA3 CDCA3 CCNA1 CCNA1 PARPBP PARPBP WEE2 WEE2 STK38 STK38 MAD2L1 MAD2L1 CKS2 CKS2 LOC102367189 LOC102367189 H3AH17_LATCH H3AH17_LATCH FOXM1 FOXM1 LOC102345131 LOC102345131 CDKN1A CDKN1A SHCBP1 SHCBP1 CKAP2L CKAP2L LOC102356575 LOC102356575 KIF14 KIF14 FAM89B FAM89B TPX2 TPX2 FBXO5 FBXO5 ATR ATR CDC14B CDC14B PTTG1 PTTG1 MELK MELK H3APT2_LATCH H3APT2_LATCH CCNJL CCNJL CCNG1 CCNG1 H3AS99_LATCH H3AS99_LATCH NEK2 NEK2 H3ASX0_LATCH H3ASX0_LATCH CKS1B CKS1B ANAPC1 ANAPC1 LOC102346472 LOC102346472 NUDC NUDC SKP2 SKP2 CDK15 CDK15 CDKN1B CDKN1B KIF23 KIF23 H3AWT9_LATCH H3AWT9_LATCH H3AWZ8_LATCH H3AWZ8_LATCH LOC102366718 LOC102366718 H3AXC7_LATCH H3AXC7_LATCH ECT2 ECT2 ANAPC13 ANAPC13 CCND1 CCND1 KIF15 KIF15 LOC102345953 LOC102345953 KIF11 KIF11 ANAPC10 ANAPC10 H3B175_LATCH H3B175_LATCH CDKN2D CDKN2D CDKN1C CDKN1C ANAPC2 ANAPC2 CDC14A CDC14A LOC102365218 LOC102365218 ESPL1 ESPL1 CCNB3 CCNB3 LOC102355470 LOC102355470 CDC27 CDC27 PCLAF PCLAF PRC1 PRC1 ANAPC7 ANAPC7 KIF18B KIF18B KIF4A KIF4A AURKA AURKA CDK17 CDK17 CEP55 CEP55 CHEK1 CHEK1 PBK PBK CDC23 CDC23 INCENP INCENP ANAPC16 ANAPC16 CDC25C CDC25C KIF19 KIF19 BIRC5 BIRC5 KNSTRN KNSTRN LOC102346156 LOC102346156 CCND2 CCND2 RACGAP1 RACGAP1 KIF17 KIF17 KNTC1 KNTC1 CIT CIT ANAPC5 ANAPC5 H3BH52_LATCH H3BH52_LATCH UBE2C UBE2C CDK2 CDK2 CDKN3 CDKN3 BICRA BICRA BUB1 BUB1 FBXO43 FBXO43 CDK1 CDK1 TTK TTK LOC102360017 LOC102360017 KIF20A KIF20A CENPF CENPF MAD1L1 MAD1L1 CDC26 CDC26 CDCA8 CDCA8 ZCWPW2 ZCWPW2 CDC20B CDC20B
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
DEPDC1DEP domain containing 1. (823 aa)
CHEK2Checkpoint kinase 2. (411 aa)
WEE1WEE1 G2 checkpoint kinase. (382 aa)
H2ZSE1_LATCHUncharacterized protein. (618 aa)
TRIP13Thyroid hormone receptor interactor 13; Belongs to the AAA ATPase family. (432 aa)
CDC16Cell division cycle 16. (545 aa)
ASPMAbnormal spindle microtubule assembly. (2977 aa)
LOC102345107Kinesin motor domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (181 aa)
LOC102352831KA1 domain-containing protein. (403 aa)
BUB3BUB3 mitotic checkpoint protein. (361 aa)
H2ZV04_LATCHAurora kinase B; Belongs to the protein kinase superfamily. (278 aa)
CCNA2Cyclin A2; Belongs to the cyclin family. (447 aa)
LOC102356560ANK_REP_REGION domain-containing protein. (128 aa)
LOC102367471Uncharacterized protein; Belongs to the cyclin family. (292 aa)
CCNE2Cyclin E2; Belongs to the cyclin family. (307 aa)
H2ZXS9_LATCHCyclin N-terminal domain-containing protein; Belongs to the cyclin family. (398 aa)
CCNE1Cyclin E1; Belongs to the cyclin family. (417 aa)
LOC102355137PH domain-containing protein. (525 aa)
H2ZZ70_LATCHNucleolar and spindle associated protein 1. (484 aa)
CCNB2Cyclin B2; Belongs to the cyclin family. (404 aa)
CDK18Cyclin dependent kinase 18. (507 aa)
H3A169_LATCHKinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (642 aa)
CCNG2Cyclin G2; Belongs to the cyclin family. (348 aa)
CUL1Cullin 1; Belongs to the cullin family. (776 aa)
LOC102365114Uncharacterized protein. (496 aa)
FZR1Fizzy and cell division cycle 20 related 1. (493 aa)
PLK3Polo like kinase 3. (617 aa)
H3A3C5_LATCHUncharacterized protein. (439 aa)
LOC102349711Uncharacterized protein. (935 aa)
CDK6Cyclin dependent kinase 6; Belongs to the protein kinase superfamily. (322 aa)
PLK1Serine/threonine-protein kinase PLK. (595 aa)
CCNICyclin I; Belongs to the cyclin family. (386 aa)
PLK5Serine/threonine-protein kinase PLK. (627 aa)
MAD2L1BPMAD2L1 binding protein. (419 aa)
H3A6M6_LATCHKinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (785 aa)
ANAPC11APC11 anaphase promoting complex subunit 11 homolog (yeast). (84 aa)
RBX1Ring-box 1. (108 aa)
CDK14Cyclin dependent kinase 14; Belongs to the protein kinase superfamily. (469 aa)
CDK4Cyclin dependent kinase 4; Belongs to the protein kinase superfamily. (306 aa)
CDC20Cell division cycle 20. (502 aa)
ZWILCHZwilch kinetochore protein. (512 aa)
CDKN2CCyclin dependent kinase inhibitor 2C. (169 aa)
CCNJCyclin J; Belongs to the cyclin family. (386 aa)
CDC25BCell division cycle 25B. (582 aa)
UBE2SUbiquitin conjugating enzyme E2 S; Belongs to the ubiquitin-conjugating enzyme family. (181 aa)
KIF2CKinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (501 aa)
CCNB1Cyclin B1; Belongs to the cyclin family. (404 aa)
CDCA3Uncharacterized protein. (351 aa)
CCNA1Cyclin A1; Belongs to the cyclin family. (433 aa)
PARPBPPARP1 binding protein. (357 aa)
WEE2Wee1-like protein kinase. (515 aa)
STK38Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (470 aa)
MAD2L1Mitotic arrest deficient 2 like 1. (202 aa)
CKS2Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. (79 aa)
LOC102367189Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (342 aa)
H3AH17_LATCHShugoshin_C domain-containing protein. (672 aa)
FOXM1Forkhead box M1. (541 aa)
LOC102345131Si:ch1073-416j23.1. (581 aa)
CDKN1ACyclin dependent kinase inhibitor 1A. (171 aa)
SHCBP1SHC binding and spindle associated 1. (640 aa)
CKAP2LUncharacterized protein. (284 aa)
LOC102356575Si:dkey-76k16.5. (260 aa)
KIF14Kinesin family member 14; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1644 aa)
FAM89BFamily with sequence similarity 89 member B. (179 aa)
TPX2TPX2 microtubule nucleation factor. (777 aa)
FBXO5F-box protein 5. (313 aa)
ATRATR serine/threonine kinase; Belongs to the PI3/PI4-kinase family. (2654 aa)
CDC14BCell division cycle 14B. (459 aa)
PTTG1Uncharacterized protein. (171 aa)
MELKMaternal embryonic leucine zipper kinase; Belongs to the protein kinase superfamily. (250 aa)
H3APT2_LATCHPH domain-containing protein. (309 aa)
CCNJLCyclin J like; Belongs to the cyclin family. (396 aa)
CCNG1Cyclin G1; Belongs to the cyclin family. (296 aa)
H3AS99_LATCHKinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (413 aa)
NEK2NIMA related kinase 2. (445 aa)
H3ASX0_LATCHKinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (397 aa)
CKS1BCyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. (81 aa)
ANAPC1Anaphase promoting complex subunit 1. (1891 aa)
LOC102346472Uncharacterized protein. (168 aa)
NUDCNuclear distribution C, dynein complex regulator. (337 aa)
SKP2S-phase kinase associated protein 2. (423 aa)
CDK15Cyclin dependent kinase 15; Belongs to the protein kinase superfamily. (397 aa)
CDKN1BCyclin dependent kinase inhibitor 1B. (198 aa)
KIF23Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (961 aa)
H3AWT9_LATCHUncharacterized protein; Belongs to the cyclin family. (271 aa)
H3AWZ8_LATCHUncharacterized protein. (385 aa)
LOC102366718Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (327 aa)
H3AXC7_LATCHKinesin family member 4; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (705 aa)
ECT2Epithelial cell transforming 2. (919 aa)
ANAPC13Anaphase promoting complex subunit 13. (75 aa)
CCND1Cyclin D1; Belongs to the cyclin family. (292 aa)
KIF15Kinesin family member 15; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1105 aa)
LOC102345953Cyclin D3; Belongs to the cyclin family. (292 aa)
KIF11Kinesin family member 11; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1059 aa)
ANAPC10Anaphase promoting complex subunit 10. (147 aa)
H3B175_LATCHTACC_C domain-containing protein. (882 aa)
CDKN2DCyclin dependent kinase inhibitor 2D. (168 aa)
CDKN1CUncharacterized protein. (215 aa)
ANAPC2Anaphase promoting complex subunit 2; Belongs to the cullin family. (816 aa)
CDC14AUncharacterized protein. (612 aa)
LOC102365218Uncharacterized protein. (210 aa)
ESPL1Extra spindle pole bodies like 1, separase. (2106 aa)
CCNB3Cyclin B3; Belongs to the cyclin family. (416 aa)
LOC102355470Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (279 aa)
CDC27Cell division cycle 27. (833 aa)
PCLAFPCNA clamp associated factor. (122 aa)
PRC1Protein regulator of cytokinesis 1. (616 aa)
ANAPC7Anaphase promoting complex subunit 7. (565 aa)
KIF18BKinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (645 aa)
KIF4AKinesin motor domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1234 aa)
AURKAAurora kinase A; Belongs to the protein kinase superfamily. (423 aa)
CDK17Cyclin dependent kinase 17. (431 aa)
CEP55Centrosomal protein 55. (468 aa)
CHEK1Checkpoint kinase 1; Belongs to the protein kinase superfamily. (475 aa)
PBKPDZ binding kinase. (336 aa)
CDC23Cell division cycle 23. (581 aa)
INCENPINCENP_ARK-bind domain-containing protein. (887 aa)
ANAPC16Anaphase promoting complex subunit 16. (119 aa)
CDC25CCell division cycle 25C. (561 aa)
KIF19Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (967 aa)
BIRC5Baculoviral IAP repeat containing 5. (139 aa)
KNSTRNUncharacterized protein. (183 aa)
LOC102346156Protein kinase domain-containing protein. (525 aa)
CCND2Cyclin D2, b; Belongs to the cyclin family. (291 aa)
RACGAP1Rac GTPase activating protein 1. (635 aa)
KIF17Kinesin family member 17; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1042 aa)
KNTC1Kinetochore associated 1. (2225 aa)
CITCitron Rho-interacting kinase; Plays a role in cytokinesis. Displays serine/threonine protein kinase activity; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (2066 aa)
ANAPC5Anaphase promoting complex subunit 5. (755 aa)
H3BH52_LATCHPH domain-containing protein. (453 aa)
UBE2CUbiquitin conjugating enzyme E2 C; Belongs to the ubiquitin-conjugating enzyme family. (179 aa)
CDK2Cyclin dependent kinase 2; Belongs to the protein kinase superfamily. (298 aa)
CDKN3Cyclin-dependent kinase inhibitor 3; May play a role in cell cycle regulation. Dual specificity phosphatase active toward substrates containing either phosphotyrosine or phosphoserine residues. (208 aa)
BICRABRD4 interacting chromatin remodeling complex associated protein. (1753 aa)
BUB1BUB1 mitotic checkpoint serine/threonine kinase. (1272 aa)
FBXO43F-box protein 43. (674 aa)
CDK1Cyclin dependent kinase 1; Belongs to the protein kinase superfamily. (302 aa)
TTKTTK protein kinase. (889 aa)
LOC102360017Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (895 aa)
KIF20AKinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (905 aa)
CENPFCentromere protein F. (3070 aa)
MAD1L1Mitotic arrest deficient 1 like 1. (684 aa)
CDC26Cell division cycle 26. (85 aa)
CDCA8Nbl1_Borealin_N domain-containing protein. (289 aa)
ZCWPW2Uncharacterized protein. (359 aa)
CDC20BCell division cycle 20B. (285 aa)
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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