(17 nodes) Aromatic amino acid family catabolic process, and Kynurenine aminotransferase activity network (Latimeria chalumnae)

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Predicted Interactions

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Your Input:
	HAAO	Uncharacterized protein. (252 aa)
	TAT	Tyrosine aminotransferase. (183 aa)
	AADAT	Aminoadipate aminotransferase. (425 aa)
	FAHD1	Fumarylacetoacetate hydrolase domain containing 1. (221 aa)
	FAHD2A	Fumarylacetoacetate hydrolase domain containing 2A. (323 aa)
	FAH	Fumarylacetoacetase. (348 aa)
	KMO	Kynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid. (474 aa)
	KYAT3	Kynurenine aminotransferase 3. (456 aa)
	HPDL	4-hydroxyphenylpyruvate dioxygenase. (442 aa)
	GSTZ1	Glutathione S-transferase zeta 1; Belongs to the GST superfamily. (223 aa)
	HGD	Homogentisate 1,2-dioxygenase. (459 aa)
	LOC102364955	4-hydroxyphenylpyruvate dioxygenase. (395 aa)
	KYAT1	Kynurenine aminotransferase 1. (457 aa)
	AFMID	Kynurenine formamidase; Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation. Kynurenine may be further oxidized to nicotinic acid, NAD(H) and NADP(H). Required for elimination of toxic metabolites. (293 aa)
	TTC36	Tetratricopeptide repeat domain 36. (216 aa)
	LOC102347411	Uncharacterized protein. (170 aa)
	KYNU	Kynureninase. (278 aa)

Your Current Organism:

Latimeria chalumnae

NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AADAT	AFMID	ENSLACP00000003451	ENSLACP00000020091	Aminoadipate aminotransferase.	Kynurenine formamidase; Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation. Kynurenine may be further oxidized to nicotinic acid, NAD(H) and NADP(H). Required for elimination of toxic metabolites.	0.937
AADAT	HAAO	ENSLACP00000003451	ENSLACP00000001313	Aminoadipate aminotransferase.	Uncharacterized protein.	0.584
AADAT	HGD	ENSLACP00000003451	ENSLACP00000017066	Aminoadipate aminotransferase.	Homogentisate 1,2-dioxygenase.	0.412
AADAT	HPDL	ENSLACP00000003451	ENSLACP00000015242	Aminoadipate aminotransferase.	4-hydroxyphenylpyruvate dioxygenase.	0.543
AADAT	KMO	ENSLACP00000003451	ENSLACP00000009168	Aminoadipate aminotransferase.	Kynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid.	0.959
AADAT	KYAT1	ENSLACP00000003451	ENSLACP00000017715	Aminoadipate aminotransferase.	Kynurenine aminotransferase 1.	0.943
AADAT	KYAT3	ENSLACP00000003451	ENSLACP00000011017	Aminoadipate aminotransferase.	Kynurenine aminotransferase 3.	0.943
AADAT	KYNU	ENSLACP00000003451	ENSLACP00000023152	Aminoadipate aminotransferase.	Kynureninase.	0.956
AADAT	LOC102364955	ENSLACP00000003451	ENSLACP00000017328	Aminoadipate aminotransferase.	4-hydroxyphenylpyruvate dioxygenase.	0.566
AFMID	AADAT	ENSLACP00000020091	ENSLACP00000003451	Kynurenine formamidase; Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation. Kynurenine may be further oxidized to nicotinic acid, NAD(H) and NADP(H). Required for elimination of toxic metabolites.	Aminoadipate aminotransferase.	0.937
AFMID	HAAO	ENSLACP00000020091	ENSLACP00000001313	Kynurenine formamidase; Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation. Kynurenine may be further oxidized to nicotinic acid, NAD(H) and NADP(H). Required for elimination of toxic metabolites.	Uncharacterized protein.	0.616
AFMID	KMO	ENSLACP00000020091	ENSLACP00000009168	Kynurenine formamidase; Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation. Kynurenine may be further oxidized to nicotinic acid, NAD(H) and NADP(H). Required for elimination of toxic metabolites.	Kynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid.	0.975
AFMID	KYAT1	ENSLACP00000020091	ENSLACP00000017715	Kynurenine formamidase; Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation. Kynurenine may be further oxidized to nicotinic acid, NAD(H) and NADP(H). Required for elimination of toxic metabolites.	Kynurenine aminotransferase 1.	0.940
AFMID	KYAT3	ENSLACP00000020091	ENSLACP00000011017	Kynurenine formamidase; Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation. Kynurenine may be further oxidized to nicotinic acid, NAD(H) and NADP(H). Required for elimination of toxic metabolites.	Kynurenine aminotransferase 3.	0.940
AFMID	KYNU	ENSLACP00000020091	ENSLACP00000023152	Kynurenine formamidase; Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation. Kynurenine may be further oxidized to nicotinic acid, NAD(H) and NADP(H). Required for elimination of toxic metabolites.	Kynureninase.	0.977
FAH	FAHD1	ENSLACP00000009155	ENSLACP00000004359	Fumarylacetoacetase.	Fumarylacetoacetate hydrolase domain containing 1.	0.959
FAH	FAHD2A	ENSLACP00000009155	ENSLACP00000006486	Fumarylacetoacetase.	Fumarylacetoacetate hydrolase domain containing 2A.	0.528
FAH	GSTZ1	ENSLACP00000009155	ENSLACP00000015735	Fumarylacetoacetase.	Glutathione S-transferase zeta 1; Belongs to the GST superfamily.	0.998
FAH	HGD	ENSLACP00000009155	ENSLACP00000017066	Fumarylacetoacetase.	Homogentisate 1,2-dioxygenase.	0.943
FAH	HPDL	ENSLACP00000009155	ENSLACP00000015242	Fumarylacetoacetase.	4-hydroxyphenylpyruvate dioxygenase.	0.764