node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AADAT | AFMID | ENSLACP00000003451 | ENSLACP00000020091 | Aminoadipate aminotransferase. | Kynurenine formamidase; Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation. Kynurenine may be further oxidized to nicotinic acid, NAD(H) and NADP(H). Required for elimination of toxic metabolites. | 0.937 |
AADAT | KMO | ENSLACP00000003451 | ENSLACP00000009168 | Aminoadipate aminotransferase. | Kynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid. | 0.959 |
AADAT | KYAT3 | ENSLACP00000003451 | ENSLACP00000011017 | Aminoadipate aminotransferase. | Kynurenine aminotransferase 3. | 0.943 |
AADAT | KYNU | ENSLACP00000003451 | ENSLACP00000023152 | Aminoadipate aminotransferase. | Kynureninase. | 0.956 |
AFMID | AADAT | ENSLACP00000020091 | ENSLACP00000003451 | Kynurenine formamidase; Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation. Kynurenine may be further oxidized to nicotinic acid, NAD(H) and NADP(H). Required for elimination of toxic metabolites. | Aminoadipate aminotransferase. | 0.937 |
AFMID | KMO | ENSLACP00000020091 | ENSLACP00000009168 | Kynurenine formamidase; Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation. Kynurenine may be further oxidized to nicotinic acid, NAD(H) and NADP(H). Required for elimination of toxic metabolites. | Kynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid. | 0.975 |
AFMID | KYAT3 | ENSLACP00000020091 | ENSLACP00000011017 | Kynurenine formamidase; Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation. Kynurenine may be further oxidized to nicotinic acid, NAD(H) and NADP(H). Required for elimination of toxic metabolites. | Kynurenine aminotransferase 3. | 0.940 |
AFMID | KYNU | ENSLACP00000020091 | ENSLACP00000023152 | Kynurenine formamidase; Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation. Kynurenine may be further oxidized to nicotinic acid, NAD(H) and NADP(H). Required for elimination of toxic metabolites. | Kynureninase. | 0.977 |
KMO | AADAT | ENSLACP00000009168 | ENSLACP00000003451 | Kynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid. | Aminoadipate aminotransferase. | 0.959 |
KMO | AFMID | ENSLACP00000009168 | ENSLACP00000020091 | Kynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid. | Kynurenine formamidase; Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation. Kynurenine may be further oxidized to nicotinic acid, NAD(H) and NADP(H). Required for elimination of toxic metabolites. | 0.975 |
KMO | KYAT3 | ENSLACP00000009168 | ENSLACP00000011017 | Kynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid. | Kynurenine aminotransferase 3. | 0.959 |
KMO | KYNU | ENSLACP00000009168 | ENSLACP00000023152 | Kynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid. | Kynureninase. | 0.998 |
KYAT3 | AADAT | ENSLACP00000011017 | ENSLACP00000003451 | Kynurenine aminotransferase 3. | Aminoadipate aminotransferase. | 0.943 |
KYAT3 | AFMID | ENSLACP00000011017 | ENSLACP00000020091 | Kynurenine aminotransferase 3. | Kynurenine formamidase; Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation. Kynurenine may be further oxidized to nicotinic acid, NAD(H) and NADP(H). Required for elimination of toxic metabolites. | 0.940 |
KYAT3 | KMO | ENSLACP00000011017 | ENSLACP00000009168 | Kynurenine aminotransferase 3. | Kynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid. | 0.959 |
KYAT3 | KYNU | ENSLACP00000011017 | ENSLACP00000023152 | Kynurenine aminotransferase 3. | Kynureninase. | 0.965 |
KYNU | AADAT | ENSLACP00000023152 | ENSLACP00000003451 | Kynureninase. | Aminoadipate aminotransferase. | 0.956 |
KYNU | AFMID | ENSLACP00000023152 | ENSLACP00000020091 | Kynureninase. | Kynurenine formamidase; Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation. Kynurenine may be further oxidized to nicotinic acid, NAD(H) and NADP(H). Required for elimination of toxic metabolites. | 0.977 |
KYNU | KMO | ENSLACP00000023152 | ENSLACP00000009168 | Kynureninase. | Kynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid. | 0.998 |
KYNU | KYAT3 | ENSLACP00000023152 | ENSLACP00000011017 | Kynureninase. | Kynurenine aminotransferase 3. | 0.965 |