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NUP155 NUP155 H2ZUL4_LATCH H2ZUL4_LATCH KCNH7 KCNH7 NTRK2 NTRK2 LOC102351831 LOC102351831 SCN10A SCN10A LOC102353246 LOC102353246 KCNE4 KCNE4 P2RX3 P2RX3 KCNE3 KCNE3 SCN1B SCN1B CACNA1G CACNA1G KCNJ8 KCNJ8 LOC102359416 LOC102359416 GPER1 GPER1 SCN2A SCN2A H3AG91_LATCH H3AG91_LATCH CACNA1I CACNA1I H3AHJ4_LATCH H3AHJ4_LATCH H3AIH7_LATCH H3AIH7_LATCH KCNQ1 KCNQ1 SCN4A SCN4A KCNH2 KCNH2 KCNH6 KCNH6 SNTA1 SNTA1 SCN3B SCN3B GJD2 GJD2 CACNB4 CACNB4 KCNE2 KCNE2 KCNE1 KCNE1 GNA11 GNA11 LOC102353803 LOC102353803 H3B867_LATCH H3B867_LATCH H3B8U3_LATCH H3B8U3_LATCH MTOR MTOR KCNB1 KCNB1 H3BE11_LATCH H3BE11_LATCH CLDN19 CLDN19 LOC102366134 LOC102366134 P2RX1 P2RX1 SCN4B SCN4B SCN2B SCN2B SCN8A SCN8A P2RX4 P2RX4 PKP2 PKP2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
NUP155Nucleoporin_C domain-containing protein. (385 aa)
H2ZUL4_LATCHUncharacterized protein. (1374 aa)
KCNH7Potassium voltage-gated channel subfamily H member 7. (594 aa)
NTRK2Tyrosine-protein kinase receptor. (819 aa)
LOC102351831Nucleoporin 155. (1004 aa)
SCN10ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1202 aa)
LOC102353246Uncharacterized protein. (374 aa)
KCNE4Potassium voltage-gated channel subfamily E regulatory subunit 4. (167 aa)
P2RX3P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (399 aa)
KCNE3Uncharacterized protein. (92 aa)
SCN1BSodium voltage-gated channel beta subunit 1. (221 aa)
CACNA1GVoltage-dependent T-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. This channel gives rise to T-type calcium currents. T-type calcium channels belong to the "low-voltage activated (LVA)" group and are strongly blocked by nickel and mibefradil. A particularity of this type of channels is an opening at quite ne [...] (2282 aa)
KCNJ8Potassium voltage-gated channel subfamily J member 8. (417 aa)
LOC102359416Uncharacterized protein. (359 aa)
GPER1G protein-coupled estrogen receptor 1; Belongs to the G-protein coupled receptor 1 family. (366 aa)
SCN2ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1702 aa)
H3AG91_LATCHUncharacterized protein. (537 aa)
CACNA1IVoltage-dependent T-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. This channel gives rise to T-type calcium currents. T-type calcium channels belong to the "low-voltage activated (LVA)" group and are strongly blocked by nickel and mibefradil. A particularity of this type of channels is an opening at quite ne [...] (1831 aa)
H3AHJ4_LATCHIon_trans domain-containing protein; Belongs to the potassium channel family. (298 aa)
H3AIH7_LATCHPAS domain-containing protein. (104 aa)
KCNQ1Potassium voltage-gated channel subfamily Q member 1; Belongs to the potassium channel family. (351 aa)
SCN4ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1836 aa)
KCNH2Cyclic nucleotide-binding domain-containing protein. (749 aa)
KCNH6Potassium voltage-gated channel subfamily H member 6. (1204 aa)
SNTA1Syntrophin alpha 1. (481 aa)
SCN3BSodium voltage-gated channel beta subunit 3. (216 aa)
GJD2Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. (304 aa)
CACNB4Calcium channel, voltage-dependent, beta 4a subunit. (477 aa)
KCNE2Potassium voltage-gated channel subfamily E regulatory subunit 2. (125 aa)
KCNE1Uncharacterized protein. (122 aa)
GNA11G protein subunit alpha 11. (433 aa)
LOC102353803Zgc:162160. (421 aa)
H3B867_LATCHSi:ch211-247n2.1. (233 aa)
H3B8U3_LATCHSerine/threonine-protein kinase TOR. (1418 aa)
MTORMechanistic target of rapamycin kinase; Belongs to the PI3/PI4-kinase family. (1009 aa)
KCNB1Potassium voltage-gated channel, Shab-related subfamily, member 1; Belongs to the potassium channel family. (677 aa)
H3BE11_LATCHUncharacterized protein. (1557 aa)
CLDN19Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (209 aa)
LOC102366134Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. (300 aa)
P2RX1P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (403 aa)
SCN4BSodium voltage-gated channel beta subunit 4. (210 aa)
SCN2BSodium voltage-gated channel beta subunit 2. (215 aa)
SCN8ASodium voltage-gated channel alpha subunit 8. (1587 aa)
P2RX4P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (391 aa)
PKP2Uncharacterized protein. (815 aa)
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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