STRINGSTRING
BMPR2 BMPR2 MSGN1 MSGN1 SRF SRF EPB41L5 EPB41L5 ITGB4 ITGB4 EPHA2 EPHA2 SMAD1 SMAD1 H3AP47_LATCH H3AP47_LATCH LOC102365298 LOC102365298 GPI GPI ACVR1 ACVR1 H3AM01_LATCH H3AM01_LATCH TBX19 TBX19 TWSG1 TWSG1 LOC102357009 LOC102357009 WNT3 WNT3 SMAD2 SMAD2 KDM6B KDM6B SFRP2 SFRP2 POFUT2 POFUT2 KDM6A KDM6A LEF1 LEF1 INHBA INHBA LOC102358266 LOC102358266 EOMES EOMES ARMC5 ARMC5 EXOC4 EXOC4 SMAD3 SMAD3 ITGA3 ITGA3 TAF10 TAF10 LOC102355265 LOC102355265 HAND1 HAND1 H3BFZ2_LATCH H3BFZ2_LATCH H3BFW7_LATCH H3BFW7_LATCH EXT2 EXT2 NF2 NF2 H3BEX6_LATCH H3BEX6_LATCH WNT3A WNT3A FGF2 FGF2 NODAL NODAL TBXT TBXT
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
BMPR2Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1037 aa)
MSGN1Mesogenin 1. (182 aa)
SRFSerum response factor. (520 aa)
EPB41L5Erythrocyte membrane protein band 4.1 like 5. (506 aa)
ITGB4Integrin beta. (1787 aa)
EPHA2Uncharacterized protein. (979 aa)
SMAD1Mothers against decapentaplegic homolog. (465 aa)
H3AP47_LATCHHomeobox domain-containing protein. (204 aa)
LOC102365298Uncharacterized protein. (427 aa)
GPIGlucose-6-phosphate isomerase; Belongs to the GPI family. (555 aa)
ACVR1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (506 aa)
H3AM01_LATCHIntegrin beta; Belongs to the integrin beta chain family. (769 aa)
TBX19T-box transcription factor 19. (373 aa)
TWSG1Twisted gastrulation BMP signaling modulator 1. (220 aa)
LOC102357009Southpaw. (414 aa)
WNT3Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (331 aa)
SMAD2Mothers against decapentaplegic homolog. (467 aa)
KDM6BLysine demethylase 6B. (1638 aa)
SFRP2Secreted frizzled related protein 2. (294 aa)
POFUT2Protein O-fucosyltransferase 2. (441 aa)
KDM6ALysine (K)-specific demethylase 6A. (1452 aa)
LEF1Lymphoid enhancer binding factor 1. (397 aa)
INHBAInhibin subunit beta A. (390 aa)
LOC102358266Dickkopf WNT signaling pathway inhibitor 1b. (261 aa)
EOMESEomesodermin. (419 aa)
ARMC5Armadillo repeat containing 5. (811 aa)
EXOC4Exocyst complex component 4. (480 aa)
SMAD3Mothers against decapentaplegic homolog. (358 aa)
ITGA3Integrin subunit alpha 3; Belongs to the integrin alpha chain family. (1012 aa)
TAF10Transcription initiation factor TFIID subunit 10; TFIID is a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors; Belongs to the TAF10 family. (142 aa)
LOC102355265Neurofibromin 2b (merlin). (577 aa)
HAND1Heart and neural crest derivatives expressed 1. (196 aa)
H3BFZ2_LATCHBHLH domain-containing protein. (165 aa)
H3BFW7_LATCHBHLH domain-containing protein. (161 aa)
EXT2Exostosin glycosyltransferase 2; Belongs to the glycosyltransferase 47 family. (718 aa)
NF2Neurofibromin 2. (595 aa)
H3BEX6_LATCHReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (307 aa)
WNT3AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (367 aa)
FGF2Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (155 aa)
NODALTGF_BETA_2 domain-containing protein. (409 aa)
TBXTT-box transcription factor T. (434 aa)
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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