(29 nodes) Stress fiber network (Latimeria chalumnae)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	PDLIM5	PDZ and LIM domain 5. (629 aa)
	DAAM2	Dishevelled associated activator of morphogenesis 2. (1034 aa)
	PDLIM4	PDZ and LIM domain 4. (233 aa)
	FHL3	Four and a half LIM domains 3. (287 aa)
	LIMCH1	LIM and calponin homology domains 1. (1477 aa)
	ZYX	Zyxin. (554 aa)
	H3A4P0_LATCH	Ig-like domain-containing protein. (174 aa)
	LDB3	LIM domain binding 3. (589 aa)
	ABLIM3	Actin binding LIM protein family member 3. (551 aa)
	BAG3	BCL2 associated athanogene 3. (561 aa)
	H3B0Y5_LATCH	Uncharacterized protein. (618 aa)
	SHROOM4	Shroom family member 4. (1398 aa)
	CNN2	Calponin; Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin, troponin C and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity. (302 aa)
	PDLIM1	PDZ and LIM domain 1. (325 aa)
	MYL9	Myosin light chain 9. (173 aa)
	ABLIM1	Actin binding LIM protein 1. (734 aa)
	H3BAT5_LATCH	Uncharacterized protein. (900 aa)
	ACTN4	Uncharacterized protein. (888 aa)
	DAAM1	Dishevelled associated activator of morphogenesis 1. (715 aa)
	FBLIM1	Filamin binding LIM protein 1. (375 aa)
	ACTN1	Uncharacterized protein. (890 aa)
	PDLIM7	PDZ and LIM domain 7. (427 aa)
	LPP	LIM domain containing preferred translocation partner in lipoma. (628 aa)
	PDLIM3	PDZ and LIM domain 3. (356 aa)
	LOC102346545	Myosin, light chain 12, genome duplicate 2. (172 aa)
	DAAM2-2	Uncharacterized protein. (72 aa)
	PGM5	Phosphoglucomutase 5; Belongs to the phosphohexose mutase family. (567 aa)
	ROR1	Receptor tyrosine kinase like orphan receptor 1. (769 aa)
	LIMA1	LIM domain and actin binding 1. (545 aa)

Your Current Organism:

Latimeria chalumnae

NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth

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structured XML interaction data, according to the 'PSI-MI' data standard

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ACTN1	LOC102346545	ENSLACP00000022097	ENSLACP00000012103	Uncharacterized protein.	Myosin, light chain 12, genome duplicate 2.	0.422
ACTN1	MYL9	ENSLACP00000022097	ENSLACP00000017959	Uncharacterized protein.	Myosin light chain 9.	0.422
ACTN1	PDLIM1	ENSLACP00000022097	ENSLACP00000016643	Uncharacterized protein.	PDZ and LIM domain 1.	0.609
ACTN1	PDLIM3	ENSLACP00000022097	ENSLACP00000012442	Uncharacterized protein.	PDZ and LIM domain 3.	0.542
ACTN1	PDLIM5	ENSLACP00000022097	ENSLACP00000009976	Uncharacterized protein.	PDZ and LIM domain 5.	0.555
ACTN1	PDLIM7	ENSLACP00000022097	ENSLACP00000022457	Uncharacterized protein.	PDZ and LIM domain 7.	0.697
ACTN4	CNN2	ENSLACP00000021197	ENSLACP00000016504	Uncharacterized protein.	Calponin; Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin, troponin C and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity.	0.418
ACTN4	LOC102346545	ENSLACP00000021197	ENSLACP00000012103	Uncharacterized protein.	Myosin, light chain 12, genome duplicate 2.	0.422
ACTN4	MYL9	ENSLACP00000021197	ENSLACP00000017959	Uncharacterized protein.	Myosin light chain 9.	0.422
ACTN4	PDLIM1	ENSLACP00000021197	ENSLACP00000016643	Uncharacterized protein.	PDZ and LIM domain 1.	0.609
ACTN4	PDLIM3	ENSLACP00000021197	ENSLACP00000012442	Uncharacterized protein.	PDZ and LIM domain 3.	0.752
ACTN4	PDLIM5	ENSLACP00000021197	ENSLACP00000009976	Uncharacterized protein.	PDZ and LIM domain 5.	0.623
ACTN4	PDLIM7	ENSLACP00000021197	ENSLACP00000022457	Uncharacterized protein.	PDZ and LIM domain 7.	0.555
CNN2	ACTN4	ENSLACP00000016504	ENSLACP00000021197	Calponin; Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin, troponin C and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity.	Uncharacterized protein.	0.418
CNN2	LOC102346545	ENSLACP00000016504	ENSLACP00000012103	Calponin; Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin, troponin C and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity.	Myosin, light chain 12, genome duplicate 2.	0.413
CNN2	MYL9	ENSLACP00000016504	ENSLACP00000017959	Calponin; Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin, troponin C and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity.	Myosin light chain 9.	0.413
CNN2	ZYX	ENSLACP00000016504	ENSLACP00000005398	Calponin; Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin, troponin C and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity.	Zyxin.	0.431
H3A4P0_LATCH	ROR1	ENSLACP00000004611	ENSLACP00000010024	Ig-like domain-containing protein.	Receptor tyrosine kinase like orphan receptor 1.	0.900
LIMCH1	PDLIM5	ENSLACP00000006608	ENSLACP00000009976	LIM and calponin homology domains 1.	PDZ and LIM domain 5.	0.412
LIMCH1	PDLIM7	ENSLACP00000006608	ENSLACP00000022457	LIM and calponin homology domains 1.	PDZ and LIM domain 7.	0.412