(33 nodes) Phosphatidylserine binding network (Latimeria chalumnae)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	SCARB2	Scavenger receptor class B member 2; Belongs to the CD36 family. (375 aa)
	GRAMD1B	GRAM domain containing 1Bb. (692 aa)
	SYT13	Synaptotagmin 13. (444 aa)
	THBS1	Thrombospondin 1. (1170 aa)
	SYT6	Synaptotagmin 6. (470 aa)
	AXL	AXL receptor tyrosine kinase. (872 aa)
	ANXA6	Annexin. (662 aa)
	SYTL2	Synaptotagmin like 2. (720 aa)
	H3B8F0_LATCH	Uncharacterized protein. (378 aa)
	SYT2	Synaptotagmin 2. (421 aa)
	OSBPL5	Oxysterol-binding protein; Belongs to the OSBP family. (884 aa)
	GAS6	Uncharacterized protein. (681 aa)
	SYT4	Synaptotagmin 4. (434 aa)
	SYT9	Synaptotagmin 9. (454 aa)
	APPL1	Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1. (709 aa)
	SYT1	Synaptotagmin 1. (384 aa)
	SYT7	Synaptotagmin 7. (286 aa)
	SYT17	Synaptotagmin 17. (473 aa)
	SYT3	Synaptotagmin 3. (538 aa)
	H3AB79_LATCH	Uncharacterized protein. (135 aa)
	CAVIN2	Caveolae associated protein 2. (427 aa)
	SYT8	Synaptotagmin 8. (400 aa)
	SYT5	Uncharacterized protein. (371 aa)
	LOC102345511	Uncharacterized protein. (292 aa)
	SYT11	Synaptotagmin 11. (429 aa)
	OSBPL8	Oxysterol-binding protein; Belongs to the OSBP family. (855 aa)
	GAP43	Growth associated protein 43. (201 aa)
	SYT10	Synaptotagmin 10. (358 aa)
	RPE65	Retinoid isomerohydrolase RPE65. (533 aa)
	SYT15	Uncharacterized protein. (424 aa)
	SMPD3	Sphingomyelin phosphodiesterase 3. (657 aa)
	APPL2	Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2. (484 aa)
	DEPDC1	DEP domain containing 1. (823 aa)

Your Current Organism:

Latimeria chalumnae

NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth

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structured XML interaction data, according to the 'PSI-MI' data standard

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
APPL1	APPL2	ENSLACP00000012610	ENSLACP00000000307	Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1.	Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2.	0.997
APPL2	APPL1	ENSLACP00000000307	ENSLACP00000012610	Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2.	Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1.	0.997
AXL	GAS6	ENSLACP00000020423	ENSLACP00000016134	AXL receptor tyrosine kinase.	Uncharacterized protein.	0.704
DEPDC1	RPE65	ENSLACP00000000081	ENSLACP00000002250	DEP domain containing 1.	Retinoid isomerohydrolase RPE65.	0.429
GAS6	AXL	ENSLACP00000016134	ENSLACP00000020423	Uncharacterized protein.	AXL receptor tyrosine kinase.	0.704
LOC102345511	SYT1	ENSLACP00000005621	ENSLACP00000011319	Uncharacterized protein.	Synaptotagmin 1.	0.665
LOC102345511	SYT2	ENSLACP00000005621	ENSLACP00000017792	Uncharacterized protein.	Synaptotagmin 2.	0.665
LOC102345511	SYT5	ENSLACP00000005621	ENSLACP00000005970	Uncharacterized protein.	Uncharacterized protein.	0.665
LOC102345511	SYT8	ENSLACP00000005621	ENSLACP00000005996	Uncharacterized protein.	Synaptotagmin 8.	0.477
LOC102345511	SYT9	ENSLACP00000005621	ENSLACP00000013978	Uncharacterized protein.	Synaptotagmin 9.	0.482
RPE65	DEPDC1	ENSLACP00000002250	ENSLACP00000000081	Retinoid isomerohydrolase RPE65.	DEP domain containing 1.	0.429
SCARB2	SYT1	ENSLACP00000003975	ENSLACP00000011319	Scavenger receptor class B member 2; Belongs to the CD36 family.	Synaptotagmin 1.	0.459
SCARB2	SYT11	ENSLACP00000003975	ENSLACP00000004647	Scavenger receptor class B member 2; Belongs to the CD36 family.	Synaptotagmin 11.	0.463
SCARB2	SYT2	ENSLACP00000003975	ENSLACP00000017792	Scavenger receptor class B member 2; Belongs to the CD36 family.	Synaptotagmin 2.	0.459
SCARB2	THBS1	ENSLACP00000003975	ENSLACP00000020712	Scavenger receptor class B member 2; Belongs to the CD36 family.	Thrombospondin 1.	0.725
SYT1	LOC102345511	ENSLACP00000011319	ENSLACP00000005621	Synaptotagmin 1.	Uncharacterized protein.	0.665
SYT1	SCARB2	ENSLACP00000011319	ENSLACP00000003975	Synaptotagmin 1.	Scavenger receptor class B member 2; Belongs to the CD36 family.	0.459
SYT1	SYT11	ENSLACP00000011319	ENSLACP00000004647	Synaptotagmin 1.	Synaptotagmin 11.	0.670
SYT1	SYT4	ENSLACP00000011319	ENSLACP00000015247	Synaptotagmin 1.	Synaptotagmin 4.	0.665
SYT1	SYT8	ENSLACP00000011319	ENSLACP00000005996	Synaptotagmin 1.	Synaptotagmin 8.	0.518