STRINGSTRING
AXL AXL H2ZS19_LATCH H2ZS19_LATCH H2ZS97_LATCH H2ZS97_LATCH APPL2 APPL2 ADIPOQ ADIPOQ OTUD5 OTUD5 ABCD1 ABCD1 H2ZUZ3_LATCH H2ZUZ3_LATCH ATG12 ATG12 LOC102358920 LOC102358920 IRAK3 IRAK3 NMBR NMBR PTPN6 PTPN6 PTGER4 PTGER4 GATA6 GATA6 SOCS5 SOCS5 GPR18 GPR18 LOC102365646 LOC102365646 NFKBIL1 NFKBIL1 NMI NMI CD200 CD200 GATA3 GATA3 PTPRC PTPRC FFAR1 FFAR1 H3A3Z5_LATCH H3A3Z5_LATCH SYT11 SYT11 IL10 IL10 LOC102358168 LOC102358168 LEF1 LEF1 ABCD2 ABCD2 FN1 FN1 IL1R2 IL1R2 LOC102362196 LOC102362196 CHRNA7 CHRNA7 SMAD7 SMAD7 EZR EZR ERRFI1 ERRFI1 GBA GBA H3ACA4_LATCH H3ACA4_LATCH LAPTM4B LAPTM4B TGFB2 TGFB2 TMEM130 TMEM130 H3AEV1_LATCH H3AEV1_LATCH DLL3 DLL3 H3AHR9_LATCH H3AHR9_LATCH DLL1 DLL1 DICER1 DICER1 PIBF1 PIBF1 TWSG1 TWSG1 HOMER3 HOMER3 SLC2A10 SLC2A10 LOC102349920 LOC102349920 LOC102346566 LOC102346566 AKAP8 AKAP8 NLRC3 NLRC3 MERTK MERTK PPARA PPARA H3ASA2_LATCH H3ASA2_LATCH DHX58 DHX58 LOC102360823 LOC102360823 NDFIP1 NDFIP1 GPATCH3 GPATCH3 PGLYRP2 PGLYRP2 POMC POMC EPHA2 EPHA2 RGCC RGCC LGR4 LGR4 LOC102360619 LOC102360619 H3AWB3_LATCH H3AWB3_LATCH TRAIP TRAIP GPNMB GPNMB MAP2K5 MAP2K5 BPIFB2 BPIFB2 INPP5D INPP5D TRAF3IP1 TRAF3IP1 ATG5 ATG5 PDCD4 PDCD4 CCR7 CCR7 LOC102356748 LOC102356748 GHSR GHSR GHRL GHRL GAS6 GAS6 TNFAIP3 TNFAIP3 CACTIN CACTIN H3B4J4_LATCH H3B4J4_LATCH N4BP1 N4BP1 UFD1 UFD1 LOC102359601 LOC102359601 INHBB INHBB TNFRSF21 TNFRSF21 NPTN NPTN H3BA69_LATCH H3BA69_LATCH TGFB3 TGFB3 SIGIRR SIGIRR H3BAW7_LATCH H3BAW7_LATCH LOC102346019 LOC102346019 ILRUN ILRUN TBX21 TBX21 CUEDC2 CUEDC2 LOC102352268 LOC102352268 ZC3H12A ZC3H12A NR1H4 NR1H4 LGALS9 LGALS9 LOC102354684 LOC102354684 TUSC2 TUSC2 LOC102362374 LOC102362374 ARG2 ARG2 NLRX1 NLRX1 LOC102354752 LOC102354752 HOMER2 HOMER2 TGFB1 TGFB1 THBS1 THBS1 ZFPM1 ZFPM1 TLR9 TLR9 LOC102350837 LOC102350837 H3BH49_LATCH H3BH49_LATCH F2 F2 CPTP CPTP CD34 CD34 RABGEF1 RABGEF1 DDIT3 DDIT3 MUL1 MUL1 C1QBP C1QBP BPIFB4 BPIFB4 APOD APOD SLC37A4 SLC37A4 HGF HGF
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
AXLAXL receptor tyrosine kinase. (872 aa)
H2ZS19_LATCHUncharacterized protein. (68 aa)
H2ZS97_LATCHTNF_2 domain-containing protein. (143 aa)
APPL2Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2. (484 aa)
ADIPOQAdiponectin, C1Q and collagen domain containing. (259 aa)
OTUD5OTU deubiquitinase 5. (534 aa)
ABCD1ATP binding cassette subfamily D member 1. (749 aa)
H2ZUZ3_LATCHUncharacterized protein. (515 aa)
ATG12Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family. (145 aa)
LOC102358920Programmed cell death 4a. (244 aa)
IRAK3Interleukin 1 receptor associated kinase 3. (546 aa)
NMBRNeuromedin B receptor; Belongs to the G-protein coupled receptor 1 family. (396 aa)
PTPN6Protein tyrosine phosphatase non-receptor type 6. (338 aa)
PTGER4Prostaglandin E receptor 4; Belongs to the G-protein coupled receptor 1 family. (455 aa)
GATA6GATA binding protein 6. (503 aa)
SOCS5Suppressor of cytokine signaling 5. (538 aa)
GPR18G protein-coupled receptor 18. (330 aa)
LOC102365646Prostaglandin E receptor 4 (subtype EP4) c; Belongs to the G-protein coupled receptor 1 family. (345 aa)
NFKBIL1Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1. (364 aa)
NMIN-myc and STAT interactor. (372 aa)
CD200Uncharacterized protein. (224 aa)
GATA3GATA binding protein 3. (447 aa)
PTPRCProtein tyrosine phosphatase receptor type C. (830 aa)
FFAR1Free fatty acid receptor 1. (279 aa)
H3A3Z5_LATCHUncharacterized protein. (679 aa)
SYT11Synaptotagmin 11. (429 aa)
IL10Interleukin 10. (185 aa)
LOC102358168G_PROTEIN_RECEP_F1_2 domain-containing protein. (352 aa)
LEF1Lymphoid enhancer binding factor 1. (397 aa)
ABCD2ATP binding cassette subfamily D member 2. (743 aa)
FN1Fibronectin 1. (2295 aa)
IL1R2Interleukin 1 receptor type 2. (378 aa)
LOC102362196Ig-like domain-containing protein. (206 aa)
CHRNA7Cholinergic receptor, nicotinic, alpha 7 (neuronal). (506 aa)
SMAD7Mothers against decapentaplegic homolog. (377 aa)
EZREzrin. (591 aa)
ERRFI1ERBB receptor feedback inhibitor 1. (468 aa)
GBAGlucosylceramidase. (517 aa)
H3ACA4_LATCHIg-like domain-containing protein. (156 aa)
LAPTM4BLysosomal protein transmembrane 4 beta. (117 aa)
TGFB2Transforming growth factor beta; Belongs to the TGF-beta family. (415 aa)
TMEM130Transmembrane protein 130. (417 aa)
H3AEV1_LATCHTNF_2 domain-containing protein. (230 aa)
DLL3Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (699 aa)
H3AHR9_LATCHG_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (336 aa)
DLL1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (723 aa)
DICER1Dicer 1, ribonuclease III; Belongs to the helicase family. Dicer subfamily. (1923 aa)
PIBF1Progesterone immunomodulatory binding factor 1. (644 aa)
TWSG1Twisted gastrulation BMP signaling modulator 1. (220 aa)
HOMER3Homer scaffold protein 3b. (361 aa)
SLC2A10Solute carrier family 2 member 10; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (535 aa)
LOC102349920Uncharacterized protein. (199 aa)
LOC102346566Annexin. (343 aa)
AKAP8A-kinase anchoring protein 8; Belongs to the AKAP95 family. (699 aa)
NLRC3NLR family CARD domain containing 3. (1005 aa)
MERTKMER proto-oncogene, tyrosine kinase. (897 aa)
PPARAPeroxisome proliferator activated receptor alpha. (468 aa)
H3ASA2_LATCHIg-like domain-containing protein. (290 aa)
DHX58DExH-box helicase 58. (680 aa)
LOC102360823G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (348 aa)
NDFIP1Nedd4 family interacting protein 1. (212 aa)
GPATCH3G-patch domain containing 3. (648 aa)
PGLYRP2Peptidoglycan recognition protein 2. (429 aa)
POMCProopiomelanocortin. (255 aa)
EPHA2Uncharacterized protein. (979 aa)
RGCCRegulator of cell cycle. (127 aa)
LGR4Leucine rich repeat containing G protein-coupled receptor 4. (955 aa)
LOC102360619Uncharacterized protein. (89 aa)
H3AWB3_LATCHUncharacterized protein. (560 aa)
TRAIPTRAF interacting protein. (461 aa)
GPNMBGlycoprotein nmb. (607 aa)
MAP2K5Mitogen-activated protein kinase kinase 5; Belongs to the protein kinase superfamily. (448 aa)
BPIFB2Uncharacterized protein. (487 aa)
INPP5DInositol polyphosphate-5-phosphatase D. (1144 aa)
TRAF3IP1TRAF3 interacting protein 1. (709 aa)
ATG5Autophagy protein 5; Involved in autophagic vesicle formation. (275 aa)
PDCD4Programmed cell death 4. (466 aa)
CCR7C-C motif chemokine receptor 7; Belongs to the G-protein coupled receptor 1 family. (379 aa)
LOC102356748Formyl peptide receptor 1. (368 aa)
GHSRGrowth hormone secretagogue receptor; Belongs to the G-protein coupled receptor 1 family. (367 aa)
GHRLMotilin_assoc domain-containing protein. (110 aa)
GAS6Uncharacterized protein. (681 aa)
TNFAIP3TNF alpha induced protein 3. (785 aa)
CACTINCactin, spliceosome C complex subunit. (768 aa)
H3B4J4_LATCHUncharacterized protein. (982 aa)
N4BP1NEDD4 binding protein 1. (806 aa)
UFD1Ubiquitin recognition factor in ER associated degradation 1. (302 aa)
LOC102359601G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (338 aa)
INHBBInhibin subunit beta B. (393 aa)
TNFRSF21TNF receptor superfamily member 21. (651 aa)
NPTNNeuroplastin. (346 aa)
H3BA69_LATCHSi:ch73-330k17.3. (196 aa)
TGFB3Transforming growth factor beta; Belongs to the TGF-beta family. (409 aa)
SIGIRRSingle Ig and TIR domain containing. (417 aa)
H3BAW7_LATCHUncharacterized protein. (190 aa)
LOC102346019C1q domain-containing protein. (226 aa)
ILRUNInflammation and lipid regulator with UBA-like and NBR1-like domains. (286 aa)
TBX21T-box transcription factor 21. (570 aa)
CUEDC2CUE domain containing 2. (154 aa)
LOC102352268Transforming growth factor beta; Belongs to the TGF-beta family. (414 aa)
ZC3H12AZinc finger CCCH-type containing 12A. (600 aa)
NR1H4Nuclear receptor subfamily 1 group H member 4. (456 aa)
LGALS9Galectin. (369 aa)
LOC102354684Immunoresponsive gene 1, like. (506 aa)
TUSC2Tumor suppressor 2, mitochondrial calcium regulator. (111 aa)
LOC102362374G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (316 aa)
ARG2Arginase. (363 aa)
NLRX1NLR family member X1. (855 aa)
LOC102354752VPS9 domain-containing protein. (197 aa)
HOMER2Homer scaffold protein 2. (354 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (401 aa)
THBS1Thrombospondin 1. (1170 aa)
ZFPM1Zinc finger protein, FOG family member 1. (1017 aa)
TLR9Toll-like receptor 9. (1039 aa)
LOC102350837G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (361 aa)
H3BH49_LATCHIg-like domain-containing protein. (195 aa)
F2Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family. (618 aa)
CPTPCeramide-1-phosphate transfer protein. (216 aa)
CD34Uncharacterized protein. (378 aa)
RABGEF1RAB guanine nucleotide exchange factor (GEF) 1. (532 aa)
DDIT3DNA damage inducible transcript 3. (256 aa)
MUL1Mitochondrial E3 ubiquitin protein ligase 1. (352 aa)
C1QBPComplement C1q binding protein. (335 aa)
BPIFB4Uncharacterized protein. (473 aa)
APODApolipoprotein D; Belongs to the calycin superfamily. Lipocalin family. (189 aa)
SLC37A4Solute carrier family 37 member 4. (441 aa)
HGFHepatocyte growth factor; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Belongs to the peptidase S1 family. Plasminogen subfamily. (720 aa)
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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