(11 nodes) Startle response network (Latimeria chalumnae)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	UCN	Urocortin. (167 aa)
	SLC6A3	Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (624 aa)
	SLITRK6	SLIT and NTRK like family member 6. (841 aa)
	DRD3	Dopamine receptor D3; Belongs to the G-protein coupled receptor 1 family. (443 aa)
	PENK	Proenkephalin. (268 aa)
	GLRB	Glycine receptor beta; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (498 aa)
	LOC102361922	Dopamine receptor D2 like; Belongs to the G-protein coupled receptor 1 family. (448 aa)
	GRIN2A	Glutamate ionotropic receptor NMDA type subunit 2A; Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. (1088 aa)
	MECP2	Methyl-CpG binding protein 2. (459 aa)
	GRIN3A	Glutamate ionotropic receptor NMDA type subunit 3A. (1109 aa)
	DRD2	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (450 aa)

Your Current Organism:

Latimeria chalumnae

NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DRD2	GRIN2A	ENSLACP00000020922	ENSLACP00000002756	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family.	Glutamate ionotropic receptor NMDA type subunit 2A; Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.	0.481
DRD2	LOC102361922	ENSLACP00000020922	ENSLACP00000008239	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family.	Dopamine receptor D2 like; Belongs to the G-protein coupled receptor 1 family.	0.901
DRD2	PENK	ENSLACP00000020922	ENSLACP00000000197	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family.	Proenkephalin.	0.413
DRD2	SLC6A3	ENSLACP00000020922	ENSLACP00000002580	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family.	Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.	0.727
DRD3	SLC6A3	ENSLACP00000002245	ENSLACP00000002580	Dopamine receptor D3; Belongs to the G-protein coupled receptor 1 family.	Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.	0.458
GRIN2A	DRD2	ENSLACP00000002756	ENSLACP00000020922	Glutamate ionotropic receptor NMDA type subunit 2A; Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family.	0.481
GRIN2A	GRIN3A	ENSLACP00000002756	ENSLACP00000013020	Glutamate ionotropic receptor NMDA type subunit 2A; Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.	Glutamate ionotropic receptor NMDA type subunit 3A.	0.873
GRIN2A	MECP2	ENSLACP00000002756	ENSLACP00000012808	Glutamate ionotropic receptor NMDA type subunit 2A; Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.	Methyl-CpG binding protein 2.	0.570
GRIN3A	GRIN2A	ENSLACP00000013020	ENSLACP00000002756	Glutamate ionotropic receptor NMDA type subunit 3A.	Glutamate ionotropic receptor NMDA type subunit 2A; Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.	0.873
LOC102361922	DRD2	ENSLACP00000008239	ENSLACP00000020922	Dopamine receptor D2 like; Belongs to the G-protein coupled receptor 1 family.	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family.	0.901
MECP2	GRIN2A	ENSLACP00000012808	ENSLACP00000002756	Methyl-CpG binding protein 2.	Glutamate ionotropic receptor NMDA type subunit 2A; Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.	0.570
PENK	DRD2	ENSLACP00000000197	ENSLACP00000020922	Proenkephalin.	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family.	0.413
SLC6A3	DRD2	ENSLACP00000002580	ENSLACP00000020922	Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family.	0.727
SLC6A3	DRD3	ENSLACP00000002580	ENSLACP00000002245	Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.	Dopamine receptor D3; Belongs to the G-protein coupled receptor 1 family.	0.458