(22 nodes) Myeloid cell activation involved in immune response network (Latimeria chalumnae)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Predicted Interactions

gene neighborhood

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Your Input:
	LOC102354752	VPS9 domain-containing protein. (197 aa)
	RASGRP1	RAS guanyl releasing protein 1. (719 aa)
	SYK	Tyrosine-protein kinase. (616 aa)
	SNAP23	Synaptosomal-associated protein; Belongs to the SNAP-25 family. (206 aa)
	CPLX2	Complexin 2. (134 aa)
	STXBP3	Syntaxin binding protein 3; Belongs to the STXBP/unc-18/SEC1 family. (597 aa)
	DNASE1L2	Deoxyribonuclease; Belongs to the DNase I family. (281 aa)
	LOC102366874	Chemokine (C-X-C motif) receptor 3, tandem duplicate 2; Belongs to the G-protein coupled receptor 1 family. (395 aa)
	LOC102356272	Lysine--tRNA ligase. (511 aa)
	MYD88	Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. (286 aa)
	LOC102349920	Uncharacterized protein. (199 aa)
	RASGRP4	RAS guanyl releasing protein 4. (692 aa)
	RABGEF1	RAB guanine nucleotide exchange factor (GEF) 1. (532 aa)
	SCNN1B	Sodium channel epithelial 1 beta subunit; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. (650 aa)
	PTGDR	Prostaglandin D2 receptor. (282 aa)
	ANXA3	Annexin. (323 aa)
	NMI	N-myc and STAT interactor. (372 aa)
	KIT	KIT proto-oncogene, receptor tyrosine kinase; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (937 aa)
	LYN	Tyrosine-protein kinase. (515 aa)
	VAMP7	Vesicle associated membrane protein 7; Belongs to the synaptobrevin family. (220 aa)
	KARS1	Lysine--tRNA ligase. (618 aa)
	IFI35	NID domain-containing protein. (215 aa)

Your Current Organism:

Latimeria chalumnae

NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ANXA3	LOC102356272	ENSLACP00000001048	ENSLACP00000018625	Annexin.	Lysine--tRNA ligase.	0.437
CPLX2	LOC102354752	ENSLACP00000014715	ENSLACP00000020287	Complexin 2.	VPS9 domain-containing protein.	0.424
CPLX2	RABGEF1	ENSLACP00000014715	ENSLACP00000021436	Complexin 2.	RAB guanine nucleotide exchange factor (GEF) 1.	0.424
CPLX2	SNAP23	ENSLACP00000014715	ENSLACP00000014172	Complexin 2.	Synaptosomal-associated protein; Belongs to the SNAP-25 family.	0.646
CPLX2	STXBP3	ENSLACP00000014715	ENSLACP00000016153	Complexin 2.	Syntaxin binding protein 3; Belongs to the STXBP/unc-18/SEC1 family.	0.557
IFI35	NMI	ENSLACP00000009062	ENSLACP00000003152	NID domain-containing protein.	N-myc and STAT interactor.	0.899
KARS1	LOC102356272	ENSLACP00000007520	ENSLACP00000018625	Lysine--tRNA ligase.	Lysine--tRNA ligase.	0.901
KIT	LYN	ENSLACP00000004383	ENSLACP00000006462	KIT proto-oncogene, receptor tyrosine kinase; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.	Tyrosine-protein kinase.	0.748
LOC102349920	MYD88	ENSLACP00000010067	ENSLACP00000019094	Uncharacterized protein.	Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response.	0.522
LOC102349920	SYK	ENSLACP00000010067	ENSLACP00000012982	Uncharacterized protein.	Tyrosine-protein kinase.	0.439
LOC102354752	CPLX2	ENSLACP00000020287	ENSLACP00000014715	VPS9 domain-containing protein.	Complexin 2.	0.424
LOC102354752	RABGEF1	ENSLACP00000020287	ENSLACP00000021436	VPS9 domain-containing protein.	RAB guanine nucleotide exchange factor (GEF) 1.	0.648
LOC102354752	VAMP7	ENSLACP00000020287	ENSLACP00000007050	VPS9 domain-containing protein.	Vesicle associated membrane protein 7; Belongs to the synaptobrevin family.	0.616
LOC102356272	ANXA3	ENSLACP00000018625	ENSLACP00000001048	Lysine--tRNA ligase.	Annexin.	0.437
LOC102356272	KARS1	ENSLACP00000018625	ENSLACP00000007520	Lysine--tRNA ligase.	Lysine--tRNA ligase.	0.901
LYN	KIT	ENSLACP00000006462	ENSLACP00000004383	Tyrosine-protein kinase.	KIT proto-oncogene, receptor tyrosine kinase; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.	0.748
LYN	SYK	ENSLACP00000006462	ENSLACP00000012982	Tyrosine-protein kinase.	Tyrosine-protein kinase.	0.909
MYD88	LOC102349920	ENSLACP00000019094	ENSLACP00000010067	Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response.	Uncharacterized protein.	0.522
MYD88	SYK	ENSLACP00000019094	ENSLACP00000012982	Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response.	Tyrosine-protein kinase.	0.609
NMI	IFI35	ENSLACP00000003152	ENSLACP00000009062	N-myc and STAT interactor.	NID domain-containing protein.	0.899