STRINGSTRING
ZFPM2 ZFPM2 TNNI3 TNNI3 EDNRA EDNRA SMAD7 SMAD7 ZMPSTE24 ZMPSTE24 TGFBR1 TGFBR1 SMAD4 SMAD4 H3AM65_LATCH H3AM65_LATCH H3APB2_LATCH H3APB2_LATCH LOC102353564 LOC102353564 TNNI1 TNNI1 MED1 MED1 IRX3 IRX3 DLL4 DLL4 PTCD2 PTCD2 LOC102350553 LOC102350553 NKX2-5 NKX2-5 TGFB1 TGFB1 TNNC1 TNNC1 HAND1 HAND1 LOC102358988 LOC102358988 ENG ENG PKP2 PKP2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ZFPM2Zinc finger protein, FOG family member 2. (979 aa)
TNNI3Uncharacterized protein. (240 aa)
EDNRAEndothelin receptor type A; Belongs to the G-protein coupled receptor 1 family. (424 aa)
SMAD7Mothers against decapentaplegic homolog. (377 aa)
ZMPSTE24CAAX prenyl protease; Proteolytically removes the C-terminal three residues of farnesylated proteins; Belongs to the peptidase M48A family. (453 aa)
TGFBR1Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (507 aa)
SMAD4MH2 domain-containing protein. (412 aa)
H3AM65_LATCHMediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (472 aa)
H3APB2_LATCHFork-head domain-containing protein. (408 aa)
LOC102353564Uncharacterized protein. (161 aa)
TNNI1Troponin I1, slow skeletal type. (171 aa)
MED1Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1401 aa)
IRX3Iroquois homeobox 3. (447 aa)
DLL4Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (688 aa)
PTCD2Pentatricopeptide repeat domain 2. (405 aa)
LOC102350553Uncharacterized protein. (232 aa)
NKX2-5NK2 homeobox 5. (296 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (401 aa)
TNNC1Troponin C type 1a (slow). (164 aa)
HAND1Heart and neural crest derivatives expressed 1. (196 aa)
LOC102358988Mothers against decapentaplegic homolog. (614 aa)
ENGEndoglin. (674 aa)
PKP2Uncharacterized protein. (815 aa)
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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