(39 nodes) Neural retina development network (Latimeria chalumnae)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	FAT3	Uncharacterized protein. (3096 aa)
	THY1	Thy-1 cell surface antigen. (165 aa)
	RPGRIP1L	RPGRIP1 like. (1318 aa)
	CNTF	Uncharacterized protein. (206 aa)
	TTC8	Tetratricopeptide repeat domain 8. (534 aa)
	CRB2	Uncharacterized protein. (1473 aa)
	SDK2	Sidekick cell adhesion molecule 2. (2107 aa)
	SLC17A8	Solute carrier family 17 member 8. (439 aa)
	ATOH7	Atonal bHLH transcription factor 7. (151 aa)
	FGF2	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (155 aa)
	PDE6C	Phosphodiesterase. (838 aa)
	NEUROD2	Neurogenic differentiation factor. (362 aa)
	SOX8	SRY-box transcription factor 8. (477 aa)
	BHLHE23	Basic helix-loop-helix family member e23. (224 aa)
	USH1C	USH1 protein network component harmonin. (830 aa)
	SDK1	Sidekick cell adhesion molecule 1. (1812 aa)
	RP1	RP1 axonemal microtubule associated. (1901 aa)
	PTF1A	Pancreas associated transcription factor 1a. (266 aa)
	NEUROD1	Neurogenic differentiation factor. (340 aa)
	NEUROD4	Neurogenic differentiation factor. (334 aa)
	TSPAN12	Tetraspanin 12; Belongs to the tetraspanin (TM4SF) family. (236 aa)
	FJX1	Four-jointed box kinase 1. (316 aa)
	IGFN1	Immunoglobulin like and fibronectin type III domain containing 1, tandem duplicate 2. (1498 aa)
	VSX1	Visual system homeobox 1. (347 aa)
	ATP2B4	Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1233 aa)
	FOXN4	Forkhead box N4. (514 aa)
	MEGF11	Multiple EGF like domains 11. (963 aa)
	IGSF22	Immunoglobulin superfamily member 22. (1326 aa)
	ZHX2	Zinc fingers and homeoboxes 2. (828 aa)
	CRB1	Crumbs cell polarity complex component 1. (1366 aa)
	RORB	RAR related orphan receptor B. (463 aa)
	RPGRIP1	RPGR interacting protein 1. (1244 aa)
	NAGLU	N-acetyl-alpha-glucosaminidase. (614 aa)
	GPM6A	Glycoprotein M6A. (298 aa)
	BSG	Basigin (Ok blood group). (368 aa)
	CABP4	Calcium binding protein 4. (240 aa)
	H3A0S5_LATCH	Uncharacterized protein. (547 aa)
	NTRK2	Tyrosine-protein kinase receptor. (819 aa)
	BBS4	Bardet-Biedl syndrome 4. (537 aa)

Your Current Organism:

Latimeria chalumnae

NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth

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TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

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structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

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node degree of proteins in your network (given the current score cut-off)

... network coordinates:

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a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ATOH7	FOXN4	ENSLACP00000019888	ENSLACP00000013000	Atonal bHLH transcription factor 7.	Forkhead box N4.	0.593
ATOH7	VSX1	ENSLACP00000019888	ENSLACP00000013422	Atonal bHLH transcription factor 7.	Visual system homeobox 1.	0.617
BBS4	RPGRIP1L	ENSLACP00000002102	ENSLACP00000022895	Bardet-Biedl syndrome 4.	RPGRIP1 like.	0.475
BBS4	TTC8	ENSLACP00000002102	ENSLACP00000022744	Bardet-Biedl syndrome 4.	Tetratricopeptide repeat domain 8.	0.997
BHLHE23	VSX1	ENSLACP00000018359	ENSLACP00000013422	Basic helix-loop-helix family member e23.	Visual system homeobox 1.	0.447
CABP4	RPGRIP1	ENSLACP00000005286	ENSLACP00000006689	Calcium binding protein 4.	RPGR interacting protein 1.	0.614
CNTF	FGF2	ENSLACP00000022760	ENSLACP00000019200	Uncharacterized protein.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.534
CNTF	NTRK2	ENSLACP00000022760	ENSLACP00000003030	Uncharacterized protein.	Tyrosine-protein kinase receptor.	0.436
FAT3	FJX1	ENSLACP00000002697	ENSLACP00000014731	Uncharacterized protein.	Four-jointed box kinase 1.	0.701
FGF2	CNTF	ENSLACP00000019200	ENSLACP00000022760	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Uncharacterized protein.	0.534
FGF2	NTRK2	ENSLACP00000019200	ENSLACP00000003030	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Tyrosine-protein kinase receptor.	0.746
FJX1	FAT3	ENSLACP00000014731	ENSLACP00000002697	Four-jointed box kinase 1.	Uncharacterized protein.	0.701
FOXN4	ATOH7	ENSLACP00000013000	ENSLACP00000019888	Forkhead box N4.	Atonal bHLH transcription factor 7.	0.593
FOXN4	PTF1A	ENSLACP00000013000	ENSLACP00000015592	Forkhead box N4.	Pancreas associated transcription factor 1a.	0.586
FOXN4	SOX8	ENSLACP00000013000	ENSLACP00000018883	Forkhead box N4.	SRY-box transcription factor 8.	0.477
FOXN4	VSX1	ENSLACP00000013000	ENSLACP00000013422	Forkhead box N4.	Visual system homeobox 1.	0.634
H3A0S5_LATCH	RPGRIP1	ENSLACP00000003246	ENSLACP00000006689	Uncharacterized protein.	RPGR interacting protein 1.	0.446
H3A0S5_LATCH	RPGRIP1L	ENSLACP00000003246	ENSLACP00000022895	Uncharacterized protein.	RPGRIP1 like.	0.698
NTRK2	CNTF	ENSLACP00000003030	ENSLACP00000022760	Tyrosine-protein kinase receptor.	Uncharacterized protein.	0.436
NTRK2	FGF2	ENSLACP00000003030	ENSLACP00000019200	Tyrosine-protein kinase receptor.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.746