STRINGSTRING
MCOLN1 MCOLN1 HCN4 HCN4 CFTR CFTR ITPR1 ITPR1 CNGA4 CNGA4 PKD2 PKD2 CNGA1 CNGA1 CNGB1 CNGB1 H3AEK5_LATCH H3AEK5_LATCH H3AFD4_LATCH H3AFD4_LATCH CNGB3 CNGB3 ITPR2 ITPR2 TPCN1 TPCN1 RYR3 RYR3 RYR2 RYR2 H3AW07_LATCH H3AW07_LATCH H3AWQ1_LATCH H3AWQ1_LATCH HCN2 HCN2 TRPA1 TRPA1 TRPM2 TRPM2 CNGA3 CNGA3 PEX5L PEX5L CNGA2 CNGA2 H3B2G0_LATCH H3B2G0_LATCH HCN1 HCN1 H3B6R7_LATCH H3B6R7_LATCH ITPR3 ITPR3 MCOLN2 MCOLN2 MCOLN3 MCOLN3 LOC102347960 LOC102347960 RYR1 RYR1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
MCOLN1Mucolipin 1. (563 aa)
HCN4Hyperpolarization activated cyclic nucleotide gated potassium channel 4. (1184 aa)
CFTRCystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane. Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelial fluid layer. (1491 aa)
ITPR1Inositol 1,4,5-trisphosphate receptor type 1. (2725 aa)
CNGA4Cyclic nucleotide gated channel subunit alpha 4. (533 aa)
PKD2Polycystin 2, transient receptor potential cation channel. (890 aa)
CNGA1Cyclic nucleotide gated channel subunit alpha 1. (542 aa)
CNGB1Cyclic nucleotide gated channel subunit beta 1. (726 aa)
H3AEK5_LATCHAquaporin 1a (Colton blood group), tandem duplicate 1; Belongs to the MIP/aquaporin (TC 1.A.8) family. (268 aa)
H3AFD4_LATCHCyclic nucleotide-binding domain-containing protein. (486 aa)
CNGB3Cyclic nucleotide gated channel subunit beta 3. (449 aa)
ITPR2Inositol 1,4,5-trisphosphate receptor type 2. (1923 aa)
TPCN1Two pore segment channel 1. (708 aa)
RYR3Uncharacterized protein. (3558 aa)
RYR2Ryanodine receptor 2b (cardiac). (3465 aa)
H3AW07_LATCHIon_trans domain-containing protein. (308 aa)
H3AWQ1_LATCHUncharacterized protein. (1126 aa)
HCN2Hyperpolarization activated cyclic nucleotide gated potassium and sodium channel 2. (946 aa)
TRPA1Transient receptor potential cation channel subfamily A member 1; Belongs to the transient receptor (TC 1.A.4) family. (1138 aa)
TRPM2Transient receptor potential cation channel subfamily M member 2. (1473 aa)
CNGA3Cyclic nucleotide gated channel subunit alpha 3. (662 aa)
PEX5LPeroxisomal biogenesis factor 5 like. (563 aa)
CNGA2Cyclic nucleotide gated channel subunit alpha 2. (745 aa)
H3B2G0_LATCHUncharacterized protein. (967 aa)
HCN1Hyperpolarization activated cyclic nucleotide gated potassium channel 1. (473 aa)
H3B6R7_LATCHIon_trans domain-containing protein. (303 aa)
ITPR3Inositol 1,4,5-trisphosphate receptor type 3. (2675 aa)
MCOLN2Mucolipin 2. (538 aa)
MCOLN3Mucolipin 3. (558 aa)
LOC102347960Two pore segment channel 3. (743 aa)
RYR1Ryanodine receptor 1. (5024 aa)
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
Server load: low (12%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.