109 items (Latimeria chalumnae) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	MLYCD	Malonyl-CoA decarboxylase. (480 aa)
	PEX7	Peroxisomal biogenesis factor 7. (140 aa)
	HACL1	2-hydroxyacyl-CoA lyase 1; Belongs to the TPP enzyme family. (554 aa)
	H2ZSB4_LATCH	AAA_lid_3 domain-containing protein. (125 aa)
	IDI1	Isopentenyl-diphosphate delta isomerase 1. (278 aa)
	H2ZSP7_LATCH	AB hydrolase-1 domain-containing protein. (107 aa)
	LOC102359944	ABC transmembrane type-1 domain-containing protein. (189 aa)
	ABCD1	ATP binding cassette subfamily D member 1. (749 aa)
	PEX5	Peroxisomal biogenesis factor 5. (666 aa)
	PEX3	Peroxisomal biogenesis factor 3. (373 aa)
	DAO	D-amino acid oxidase. (347 aa)
	FAR2	Fatty acyl-CoA reductase; Catalyzes the reduction of fatty acyl-CoA to fatty alcohols. (429 aa)
	SZT2	Uncharacterized protein. (3053 aa)
	LOC102354541	AB hydrolase-1 domain-containing protein. (314 aa)
	LOC102355603	Carnitine O-acetyltransferase b. (630 aa)
	TMEM135	Transmembrane protein 135. (464 aa)
	PEX11G	Peroxisomal biogenesis factor 11 gamma. (158 aa)
	ACSL4	Acyl-CoA synthetase long chain family member 4. (713 aa)
	H3A1U5_LATCH	Uncharacterized protein. (129 aa)
	H3A2L0_LATCH	Uncharacterized protein. (143 aa)
	HSD17B4	Hydroxysteroid 17-beta dehydrogenase 4. (740 aa)
	MARF1	Meiosis regulator and mRNA stability factor 1. (1759 aa)
	ECI2	Enoyl-CoA delta isomerase 2. (409 aa)
	PHYH	Phytanoyl-CoA 2-hydroxylase. (372 aa)
	ACSL3	Acyl-CoA synthetase long chain family member 3. (711 aa)
	PECR	Peroxisomal trans-2-enoyl-CoA reductase; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (306 aa)
	SLC25A17	Solute carrier family 25 member 17; Belongs to the mitochondrial carrier (TC 2.A.29) family. (268 aa)
	PJVK	Pejvakin. (355 aa)
	ABCD3	ATP binding cassette subfamily D member 3. (684 aa)
	TRIM37	Tripartite motif containing 37. (939 aa)
	HAO1	Hydroxyacid oxidase 1. (370 aa)
	ABCD2	ATP binding cassette subfamily D member 2. (743 aa)
	PODN	Podocan. (621 aa)
	PAOX	Si:dkey-275b16.2. (503 aa)
	MGAT4A	Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase A. (530 aa)
	ACSL6	Uncharacterized protein. (749 aa)
	AGXT	Serine--pyruvate aminotransferase. (426 aa)
	PXMP4	Peroxisomal membrane protein 4; Belongs to the peroxisomal membrane protein PXMP2/4 family. (212 aa)
	PEX13	SH3 domain-containing protein. (381 aa)
	ATAD1	ATPase family AAA domain containing 1; Belongs to the AAA ATPase family. (367 aa)
	CROT	Carnitine O-octanoyltransferase. (612 aa)
	LACC1	Laccase (multicopper oxidoreductase) domain containing 1. (442 aa)
	CAT	Catalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide. (521 aa)
	FAR1	Fatty acyl-CoA reductase; Catalyzes the reduction of fatty acyl-CoA to fatty alcohols. (515 aa)
	PEX19	Peroxisomal biogenesis factor 19. (292 aa)
	ACAD11	APH domain-containing protein. (405 aa)
	PIPOX	Pipecolic acid and sarcosine oxidase. (394 aa)
	PNPLA8	Patatin like phospholipase domain containing 8. (796 aa)
	HMGCR	3-hydroxy-3-methylglutaryl coenzyme A reductase. (882 aa)
	MFF	Mitochondrial fission factor. (345 aa)
	AGPS	Alkylglycerone-phosphate synthase; Catalyzes the exchange of an acyl for a long-chain alkyl group and the formation of the ether bond in the biosynthesis of ether phospholipids; Belongs to the FAD-binding oxidoreductase/transferase type 4 family. (631 aa)
	DDO	D-aspartate oxidase. (338 aa)
	SYT7	Synaptotagmin 7. (286 aa)
	HAO2	Hydroxyacid oxidase 2. (356 aa)
	H3AN88_LATCH	Uncharacterized protein. (780 aa)
	DNM1L	Dynamin 1 like; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (778 aa)
	H3APB7_LATCH	Mitochondrial E3 ubiquitin protein ligase 1a. (243 aa)
	PEX1	Peroxisomal biogenesis factor 1. (1292 aa)
	HSDL2	Hydroxysteroid dehydrogenase like 2. (414 aa)
	PEX14	Peroxisomal biogenesis factor 14. (317 aa)
	LOC102360171	Si:dkey-32e23.4; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (426 aa)
	PEX10	Peroxisomal biogenesis factor 10. (315 aa)
	ACOX2	Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family. (618 aa)
	LOC102359768	Dehydrogenase/reductase (SDR family) member 4. (284 aa)
	RIDA	Reactive intermediate imine deaminase A homolog. (137 aa)
	PXMP2	Peroxisomal membrane protein 2; Belongs to the peroxisomal membrane protein PXMP2/4 family. (192 aa)
	ACOX3	Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family. (708 aa)
	MVK	Mevalonate kinase; Catalyzes the phosphorylation of mevalonate to mevalonate 5- phosphate, a key step in isoprenoid and cholesterol biosynthesis. Belongs to the GHMP kinase family. Mevalonate kinase subfamily. (401 aa)
	CRAT	Carnitine O-acetyltransferase; Belongs to the carnitine/choline acetyltransferase family. (631 aa)
	URAD	Ureidoimidazoline (2-oxo-4-hydroxy-4-carboxy-5-) decarboxylase. (175 aa)
	PEX2	Peroxisomal biogenesis factor 2. (299 aa)
	MUL1	Mitochondrial E3 ubiquitin protein ligase 1. (352 aa)
	LOC102360643	Uricase; Catalyzes the oxidation of uric acid to 5-hydroxyisourate, which is further processed to form (S)-allantoin. Belongs to the uricase family. (306 aa)
	FAM185A	Family with sequence similarity 185 member A. (385 aa)
	M3XGG2_LATCH	5-hydroxyisourate hydrolase; Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily. (141 aa)
	ACOT8	Acyl-CoA thioesterase 8. (332 aa)
	ECH1	Enoyl-CoA hydratase 1. (323 aa)
	PEX16	Peroxisomal membrane protein PEX16. (325 aa)
	ABCD4	ATP-binding cassette, sub-family D (ALD), member 4. (438 aa)
	PEX11A	Peroxisomal biogenesis factor 11 alpha. (249 aa)
	PEX26	Peroxisomal biogenesis factor 26. (303 aa)
	IDH2	Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (402 aa)
	PEX11B	Peroxisomal biogenesis factor 11 beta. (244 aa)
	PRDX5	Peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Prx5 subfamily. (190 aa)
	DECR2	2,4-dienoyl-CoA reductase 2. (300 aa)
	ACOX1	Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family. (661 aa)
	PEX12	Peroxisome assembly protein 12; Required for protein import into peroxisomes. Belongs to the pex2/pex10/pex12 family. (356 aa)
	NUDT17	Nudix hydrolase 17. (292 aa)
	TYSND1	Trypsin domain containing 1. (589 aa)
	ACOXL	Acyl-CoA oxidase like. (219 aa)
	LOC102358226	AAA domain-containing protein. (235 aa)
	TMEM35A	Transmembrane protein 35A. (166 aa)
	GNPAT	Glyceronephosphate O-acyltransferase; Belongs to the GPAT/DAPAT family. (686 aa)
	PIK3C3	Phosphatidylinositol 3-kinase catalytic subunit type 3. (825 aa)
	ACAA1	Acetyl-CoA acyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family. (425 aa)
	PHYHD1	Phytanoyl-CoA dioxygenase domain containing 1. (293 aa)
	NUDT12	Nudix hydrolase 12. (460 aa)
	FNDC5	Fibronectin type III domain containing 5. (207 aa)
	IDH1	Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (414 aa)
	H3B2Z1_LATCH	Uncharacterized protein. (109 aa)
	PODNL1	Podocan like 1. (599 aa)
	ZADH2	Zinc binding alcohol dehydrogenase domain containing 2. (403 aa)
	PEX5L	Peroxisomal biogenesis factor 5 like. (563 aa)
	LOC102350445	Malate synthase-like. (539 aa)
	LONP2	Lon protease homolog 2, peroxisomal; ATP-dependent serine protease that mediates the selective degradation of misfolded and unassembled polypeptides in the peroxisomal matrix. Necessary for type 2 peroxisome targeting signal (PTS2)-containing protein processing and facilitates peroxisome matrix protein import; Belongs to the peptidase S16 family. ECO:0000256\|PROSITE-. (855 aa)
	AMACR	Alpha-methylacyl-CoA racemase. (402 aa)
	NUDT19	Nudix hydrolase 19. (388 aa)
	IDE	Insulin degrading enzyme; Belongs to the peptidase M16 family. (1016 aa)
	EHHADH	Enoyl-CoA hydratase and 3-hydroxyacyl CoA dehydrogenase. (537 aa)

Your Current Organism:

Latimeria chalumnae

NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ABCD1	ABCD2	ENSLACP00000001162	ENSLACP00000005686	ATP binding cassette subfamily D member 1.	ATP binding cassette subfamily D member 2.	0.901
ABCD1	ABCD3	ENSLACP00000001162	ENSLACP00000005299	ATP binding cassette subfamily D member 1.	ATP binding cassette subfamily D member 3.	0.792
ABCD1	ABCD4	ENSLACP00000001162	ENSLACP00000021089	ATP binding cassette subfamily D member 1.	ATP-binding cassette, sub-family D (ALD), member 4.	0.654
ABCD1	ACOX1	ENSLACP00000001162	ENSLACP00000019825	ATP binding cassette subfamily D member 1.	Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family.	0.575
ABCD1	ACSL3	ENSLACP00000001162	ENSLACP00000004477	ATP binding cassette subfamily D member 1.	Acyl-CoA synthetase long chain family member 3.	0.417
ABCD1	ACSL4	ENSLACP00000001162	ENSLACP00000003329	ATP binding cassette subfamily D member 1.	Acyl-CoA synthetase long chain family member 4.	0.417
ABCD1	ATAD1	ENSLACP00000001162	ENSLACP00000008272	ATP binding cassette subfamily D member 1.	ATPase family AAA domain containing 1; Belongs to the AAA ATPase family.	0.578
ABCD1	ECH1	ENSLACP00000001162	ENSLACP00000021236	ATP binding cassette subfamily D member 1.	Enoyl-CoA hydratase 1.	0.472
ABCD1	ECI2	ENSLACP00000001162	ENSLACP00000004153	ATP binding cassette subfamily D member 1.	Enoyl-CoA delta isomerase 2.	0.685
ABCD1	FAM185A	ENSLACP00000001162	ENSLACP00000021821	ATP binding cassette subfamily D member 1.	Family with sequence similarity 185 member A.	0.662
ABCD1	H2ZSB4_LATCH	ENSLACP00000001162	ENSLACP00000000285	ATP binding cassette subfamily D member 1.	AAA_lid_3 domain-containing protein.	0.578
ABCD1	H3AN88_LATCH	ENSLACP00000001162	ENSLACP00000011109	ATP binding cassette subfamily D member 1.	Uncharacterized protein.	0.443
ABCD1	HSD17B4	ENSLACP00000001162	ENSLACP00000003889	ATP binding cassette subfamily D member 1.	Hydroxysteroid 17-beta dehydrogenase 4.	0.476
ABCD1	HSDL2	ENSLACP00000001162	ENSLACP00000012557	ATP binding cassette subfamily D member 1.	Hydroxysteroid dehydrogenase like 2.	0.504
ABCD1	LOC102358226	ENSLACP00000001162	ENSLACP00000019027	ATP binding cassette subfamily D member 1.	AAA domain-containing protein.	0.541
ABCD1	LOC102359944	ENSLACP00000001162	ENSLACP00000000437	ATP binding cassette subfamily D member 1.	ABC transmembrane type-1 domain-containing protein.	0.632
ABCD1	PEX11A	ENSLACP00000001162	ENSLACP00000020644	ATP binding cassette subfamily D member 1.	Peroxisomal biogenesis factor 11 alpha.	0.679
ABCD1	PEX11B	ENSLACP00000001162	ENSLACP00000020386	ATP binding cassette subfamily D member 1.	Peroxisomal biogenesis factor 11 beta.	0.679
ABCD1	PEX11G	ENSLACP00000001162	ENSLACP00000003324	ATP binding cassette subfamily D member 1.	Peroxisomal biogenesis factor 11 gamma.	0.618
ABCD1	PEX12	ENSLACP00000001162	ENSLACP00000019682	ATP binding cassette subfamily D member 1.	Peroxisome assembly protein 12; Required for protein import into peroxisomes. Belongs to the pex2/pex10/pex12 family.	0.736