(11 nodes) Glycine metabolic process network (Latimeria chalumnae)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

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protein homology

Your Input:
	AMT	Aminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine; Belongs to the GcvT family. (422 aa)
	AGXT2	Alanine--glyoxylate aminotransferase 2; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (516 aa)
	HAO1	Hydroxyacid oxidase 1. (370 aa)
	GCSH	Glycine cleavage system H protein; The H protein shuttles the methylamine group of glycine from the P protein to the T protein; Belongs to the GcvH family. (177 aa)
	DHFR	Dihydrofolate reductase. (206 aa)
	GLDC	Glycine cleavage system P protein; The glycine cleavage system catalyzes the degradation of glycine. (914 aa)
	SHMT1	Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. (474 aa)
	LOC102360320	L-threonine dehydrogenase. (371 aa)
	PHGDH	Phosphoglycerate dehydrogenase. (522 aa)
	SHMT2	Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. (542 aa)
	LOC102346865	Threonine aldolase 1. (417 aa)

Your Current Organism:

Latimeria chalumnae

NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AGXT2	AMT	ENSLACP00000004295	ENSLACP00000017424	Alanine--glyoxylate aminotransferase 2; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.	Aminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine; Belongs to the GcvT family.	0.407
AGXT2	GLDC	ENSLACP00000004295	ENSLACP00000010100	Alanine--glyoxylate aminotransferase 2; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.	Glycine cleavage system P protein; The glycine cleavage system catalyzes the degradation of glycine.	0.956
AGXT2	HAO1	ENSLACP00000004295	ENSLACP00000005585	Alanine--glyoxylate aminotransferase 2; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.	Hydroxyacid oxidase 1.	0.868
AGXT2	LOC102346865	ENSLACP00000004295	ENSLACP00000019944	Alanine--glyoxylate aminotransferase 2; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.	Threonine aldolase 1.	0.936
AGXT2	SHMT2	ENSLACP00000004295	ENSLACP00000021709	Alanine--glyoxylate aminotransferase 2; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.	Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family.	0.925
AMT	AGXT2	ENSLACP00000017424	ENSLACP00000004295	Aminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine; Belongs to the GcvT family.	Alanine--glyoxylate aminotransferase 2; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.	0.407
AMT	DHFR	ENSLACP00000017424	ENSLACP00000007736	Aminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine; Belongs to the GcvT family.	Dihydrofolate reductase.	0.953
AMT	GCSH	ENSLACP00000017424	ENSLACP00000006340	Aminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine; Belongs to the GcvT family.	Glycine cleavage system H protein; The H protein shuttles the methylamine group of glycine from the P protein to the T protein; Belongs to the GcvH family.	0.999
AMT	GLDC	ENSLACP00000017424	ENSLACP00000010100	Aminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine; Belongs to the GcvT family.	Glycine cleavage system P protein; The glycine cleavage system catalyzes the degradation of glycine.	0.999
AMT	HAO1	ENSLACP00000017424	ENSLACP00000005585	Aminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine; Belongs to the GcvT family.	Hydroxyacid oxidase 1.	0.506
AMT	LOC102346865	ENSLACP00000017424	ENSLACP00000019944	Aminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine; Belongs to the GcvT family.	Threonine aldolase 1.	0.712
AMT	PHGDH	ENSLACP00000017424	ENSLACP00000015657	Aminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine; Belongs to the GcvT family.	Phosphoglycerate dehydrogenase.	0.723
AMT	SHMT1	ENSLACP00000017424	ENSLACP00000011159	Aminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine; Belongs to the GcvT family.	Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family.	0.911
AMT	SHMT2	ENSLACP00000017424	ENSLACP00000021709	Aminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine; Belongs to the GcvT family.	Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family.	0.990
DHFR	AMT	ENSLACP00000007736	ENSLACP00000017424	Dihydrofolate reductase.	Aminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine; Belongs to the GcvT family.	0.953
DHFR	GCSH	ENSLACP00000007736	ENSLACP00000006340	Dihydrofolate reductase.	Glycine cleavage system H protein; The H protein shuttles the methylamine group of glycine from the P protein to the T protein; Belongs to the GcvH family.	0.926
DHFR	GLDC	ENSLACP00000007736	ENSLACP00000010100	Dihydrofolate reductase.	Glycine cleavage system P protein; The glycine cleavage system catalyzes the degradation of glycine.	0.928
DHFR	SHMT1	ENSLACP00000007736	ENSLACP00000011159	Dihydrofolate reductase.	Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family.	0.852
DHFR	SHMT2	ENSLACP00000007736	ENSLACP00000021709	Dihydrofolate reductase.	Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family.	0.975
GCSH	AMT	ENSLACP00000006340	ENSLACP00000017424	Glycine cleavage system H protein; The H protein shuttles the methylamine group of glycine from the P protein to the T protein; Belongs to the GcvH family.	Aminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine; Belongs to the GcvT family.	0.999