STRINGSTRING
LOC102358988 LOC102358988 TCF15 TCF15 GPI GPI LOC102354258 LOC102354258 PALB2 PALB2 ACVR2A ACVR2A SMO SMO EOMES EOMES ARMC5 ARMC5 EXOC4 EXOC4 TAF10 TAF10 ITGA3 ITGA3 LOC102358266 LOC102358266 INHBA INHBA LEF1 LEF1 FOXC1 FOXC1 KDM6A KDM6A LOC102353832 LOC102353832 NF2 NF2 POFUT2 POFUT2 SFRP2 SFRP2 FGF8 FGF8 KDM6B KDM6B SETD2 SETD2 SMAD2 SMAD2 WNT3 WNT3 SMAD4 SMAD4 FOXS1 FOXS1 LOC102357009 LOC102357009 POGLUT1 POGLUT1 TWSG1 TWSG1 AMH AMH TBX19 TBX19 H3AM01_LATCH H3AM01_LATCH EXT2 EXT2 ACVR1 ACVR1 H3AP47_LATCH H3AP47_LATCH H3APB2_LATCH H3APB2_LATCH SMAD3 SMAD3 H3ARL7_LATCH H3ARL7_LATCH LOC102365298 LOC102365298 SMAD1 SMAD1 EPHA2 EPHA2 IRX3 IRX3 ACVR2B ACVR2B TP63 TP63 ITGB4 ITGB4 FOXC2 FOXC2 NUP133 NUP133 SCX SCX EPB41L5 EPB41L5 SRF SRF MSGN1 MSGN1 BMPR2 BMPR2 TBXT TBXT NODAL NODAL FGF2 FGF2 WNT3A WNT3A H3BEX6_LATCH H3BEX6_LATCH H3BFW7_LATCH H3BFW7_LATCH H3BFZ2_LATCH H3BFZ2_LATCH HAND1 HAND1 LOC102355265 LOC102355265
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LOC102358988Mothers against decapentaplegic homolog. (614 aa)
TCF15Transcription factor 15. (163 aa)
GPIGlucose-6-phosphate isomerase; Belongs to the GPI family. (555 aa)
LOC102354258Si:ch211-246m6.4. (181 aa)
PALB2PALB2_WD40 domain-containing protein. (874 aa)
ACVR2ASerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (512 aa)
SMOSmoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family. (820 aa)
EOMESEomesodermin. (419 aa)
ARMC5Armadillo repeat containing 5. (811 aa)
EXOC4Exocyst complex component 4. (480 aa)
TAF10Transcription initiation factor TFIID subunit 10; TFIID is a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors; Belongs to the TAF10 family. (142 aa)
ITGA3Integrin subunit alpha 3; Belongs to the integrin alpha chain family. (1012 aa)
LOC102358266Dickkopf WNT signaling pathway inhibitor 1b. (261 aa)
INHBAInhibin subunit beta A. (390 aa)
LEF1Lymphoid enhancer binding factor 1. (397 aa)
FOXC1Forkhead box C1. (471 aa)
KDM6ALysine (K)-specific demethylase 6A. (1452 aa)
LOC102353832Uncharacterized protein. (170 aa)
NF2Neurofibromin 2. (595 aa)
POFUT2Protein O-fucosyltransferase 2. (441 aa)
SFRP2Secreted frizzled related protein 2. (294 aa)
FGF8Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (213 aa)
KDM6BLysine demethylase 6B. (1638 aa)
SETD2SET domain containing 2, histone lysine methyltransferase. (2541 aa)
SMAD2Mothers against decapentaplegic homolog. (467 aa)
WNT3Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (331 aa)
SMAD4MH2 domain-containing protein. (412 aa)
FOXS1Fork-head domain-containing protein. (155 aa)
LOC102357009Southpaw. (414 aa)
POGLUT1Protein O-glucosyltransferase 1. (351 aa)
TWSG1Twisted gastrulation BMP signaling modulator 1. (220 aa)
AMHAnti-Mullerian hormone. (562 aa)
TBX19T-box transcription factor 19. (373 aa)
H3AM01_LATCHIntegrin beta; Belongs to the integrin beta chain family. (769 aa)
EXT2Exostosin glycosyltransferase 2; Belongs to the glycosyltransferase 47 family. (718 aa)
ACVR1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (506 aa)
H3AP47_LATCHHomeobox domain-containing protein. (204 aa)
H3APB2_LATCHFork-head domain-containing protein. (408 aa)
SMAD3Mothers against decapentaplegic homolog. (358 aa)
H3ARL7_LATCHFork-head domain-containing protein. (195 aa)
LOC102365298Uncharacterized protein. (427 aa)
SMAD1Mothers against decapentaplegic homolog. (465 aa)
EPHA2Uncharacterized protein. (979 aa)
IRX3Iroquois homeobox 3. (447 aa)
ACVR2BSerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (515 aa)
TP63Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (637 aa)
ITGB4Integrin beta. (1787 aa)
FOXC2Forkhead box C2. (469 aa)
NUP133Nucleoporin 133; Belongs to the actin family. (1421 aa)
SCXScleraxis bHLH transcription factor. (182 aa)
EPB41L5Erythrocyte membrane protein band 4.1 like 5. (506 aa)
SRFSerum response factor. (520 aa)
MSGN1Mesogenin 1. (182 aa)
BMPR2Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1037 aa)
TBXTT-box transcription factor T. (434 aa)
NODALTGF_BETA_2 domain-containing protein. (409 aa)
FGF2Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (155 aa)
WNT3AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (367 aa)
H3BEX6_LATCHReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (307 aa)
H3BFW7_LATCHBHLH domain-containing protein. (161 aa)
H3BFZ2_LATCHBHLH domain-containing protein. (165 aa)
HAND1Heart and neural crest derivatives expressed 1. (196 aa)
LOC102355265Neurofibromin 2b (merlin). (577 aa)
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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