(90 nodes) Sensory perception of sound network (Latimeria chalumnae)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	H2ZSI5_LATCH	Uncharacterized protein. (91 aa)
	PDZD7	PDZ domain containing 7. (505 aa)
	TECTA	Tectorin alpha. (2122 aa)
	FZD4	Frizzled class receptor 4; Belongs to the G-protein coupled receptor Fz/Smo family. (530 aa)
	SLC1A3	Amino acid transporter. (441 aa)
	H2ZY86_LATCH	Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family. (177 aa)
	H2ZYB6_LATCH	Uncharacterized protein. (324 aa)
	LOXHD1	Lipoxygenase homology domains 1. (2403 aa)
	CFAP57	Cilia and flagella associated protein 57. (743 aa)
	MYO3A	Myosin IIIA; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (600 aa)
	OTOS	Otospiralin. (87 aa)
	H3A1B7_LATCH	Uncharacterized protein. (378 aa)
	GABRA5	Gamma-aminobutyric acid type A receptor alpha5 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (454 aa)
	MYO7A	Myosin VIIA; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2185 aa)
	SCARB2	Scavenger receptor class B member 2; Belongs to the CD36 family. (375 aa)
	TMC2	Transmembrane channel-like protein. (908 aa)
	KIT	KIT proto-oncogene, receptor tyrosine kinase; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (937 aa)
	H3A478_LATCH	PDZ domain-containing protein. (297 aa)
	EYA4	Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family. (620 aa)
	H3A4P0_LATCH	Ig-like domain-containing protein. (174 aa)
	H3A4S8_LATCH	Uncharacterized protein. (2030 aa)
	PJVK	Pejvakin. (355 aa)
	SLC26A5	Solute carrier family 26 member 5. (755 aa)
	EPYC	Epiphycan. (266 aa)
	NIPBL	Nipped-B protein. (2707 aa)
	MYO3B	Myosin IIIB; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (805 aa)
	PKHD1L1	PKHD1 like 1. (4001 aa)
	H3A9U0_LATCH	PDZ domain-containing protein. (234 aa)
	MKKS	McKusick-Kaufman syndrome. (575 aa)
	HEXB	Beta-hexosaminidase. (552 aa)
	LOC102362960	Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. (256 aa)
	RIPOR2	RHO family interacting cell polarization regulator 2. (1059 aa)
	LRIG1	Leucine rich repeats and immunoglobulin like domains 1. (1097 aa)
	GRXCR1	Glutaredoxin and cysteine rich domain containing 1. (213 aa)
	LOC102363509	Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. (248 aa)
	H3AHJ4_LATCH	Ion_trans domain-containing protein; Belongs to the potassium channel family. (298 aa)
	MYO6	Myosin VI; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1230 aa)
	H3AIG1_LATCH	Uncharacterized protein. (317 aa)
	PTPRQ	Protein tyrosine phosphatase receptor type Q. (1795 aa)
	H3AIX4_LATCH	Uncharacterized protein. (418 aa)
	CLDN7	Claudin 7b. (145 aa)
	DDIT3	DNA damage inducible transcript 3. (256 aa)
	KCNQ1	Potassium voltage-gated channel subfamily Q member 1; Belongs to the potassium channel family. (351 aa)
	H3AJV8_LATCH	Beta_helix domain-containing protein. (504 aa)
	CRYM	Crystallin mu. (226 aa)
	ROR1	Receptor tyrosine kinase like orphan receptor 1. (769 aa)
	ADGRV1	Adhesion G protein-coupled receptor V1. (5847 aa)
	CNTN5	Contactin 5. (669 aa)
	H3AM41_LATCH	G8 domain-containing protein. (1861 aa)
	UCN	Urocortin. (167 aa)
	ESPNL	Espin like. (997 aa)
	NAV2	Neuron navigator 2a. (1109 aa)
	USH1G	USH1 protein network component sans. (471 aa)
	COCH	Cochlin. (547 aa)
	H3ARY7_LATCH	Uncharacterized protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2293 aa)
	MARVELD2	MARVEL domain containing 2. (563 aa)
	GRXCR2	Glutaredoxin and cysteine rich domain containing 2. (260 aa)
	USP53	Ubiquitin specific peptidase 53. (1167 aa)
	LOC102350991	Uncharacterized protein. (1471 aa)
	WFS1	Wolframin ER transmembrane glycoprotein. (876 aa)
	TMTC4	Transmembrane O-mannosyltransferase targeting cadherins 4. (743 aa)
	LHFPL5	LHFPL tetraspan subfamily member 5. (222 aa)
	SOBP	Sine oculis binding protein homolog. (634 aa)
	TMIE	Transmembrane inner ear. (130 aa)
	PGAP1	GPI inositol-deacylase; Involved in inositol deacylation of GPI-anchored proteins. GPI inositol deacylation may important for efficient transport of GPI- anchored proteins from the endoplasmic reticulum to the Golgi. (722 aa)
	LOC102359345	Transmembrane O-methyltransferase. (268 aa)
	LHFPL4	LHFPL tetraspan subfamily member 4. (151 aa)
	H3AZT3_LATCH	GRB2 related adaptor protein b. (99 aa)
	TPRN	Taperin. (771 aa)
	HPN	Hepsin; Belongs to the peptidase S1 family. (415 aa)
	CDKN2D	Cyclin dependent kinase inhibitor 2D. (168 aa)
	CDC14A	Uncharacterized protein. (612 aa)
	OTOA	Otoancorin. (997 aa)
	H3B339_LATCH	Uncharacterized protein. (531 aa)
	FBXO11	F-box protein 11. (879 aa)
	TSPEAR	Thrombospondin type laminin G domain and EAR repeats. (426 aa)
	OTOG	Otogelin. (2804 aa)
	EYA1	Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family. (646 aa)
	MYO15A	Myosin XVA; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (3520 aa)
	MYO7B	Myosin VIIB; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2098 aa)
	CLRN3	Clarin 3. (230 aa)
	OTOGL	Otogelin like. (2821 aa)
	USH1C	USH1 protein network component harmonin. (830 aa)
	ESPN	Espin. (862 aa)
	LRIG2	Leucine rich repeats and immunoglobulin like domains 2. (1024 aa)
	H3BBK0_LATCH	Uncharacterized protein. (783 aa)
	P2RX2	P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (388 aa)
	SLC17A8	Solute carrier family 17 member 8. (439 aa)
	HOMER2	Homer scaffold protein 2. (354 aa)
	SPNS2	Sphingolipid transporter 2. (362 aa)

Your Current Organism:

Latimeria chalumnae

NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ADGRV1	GRXCR1	ENSLACP00000010057	ENSLACP00000008466	Adhesion G protein-coupled receptor V1.	Glutaredoxin and cysteine rich domain containing 1.	0.441
ADGRV1	H3A478_LATCH	ENSLACP00000010057	ENSLACP00000004449	Adhesion G protein-coupled receptor V1.	PDZ domain-containing protein.	0.543
ADGRV1	H3A4S8_LATCH	ENSLACP00000010057	ENSLACP00000004649	Adhesion G protein-coupled receptor V1.	Uncharacterized protein.	0.535
ADGRV1	H3A9U0_LATCH	ENSLACP00000010057	ENSLACP00000006411	Adhesion G protein-coupled receptor V1.	PDZ domain-containing protein.	0.530
ADGRV1	H3AIG1_LATCH	ENSLACP00000010057	ENSLACP00000009432	Adhesion G protein-coupled receptor V1.	Uncharacterized protein.	0.543
ADGRV1	LOC102350991	ENSLACP00000010057	ENSLACP00000012767	Adhesion G protein-coupled receptor V1.	Uncharacterized protein.	0.755
ADGRV1	MYO6	ENSLACP00000010057	ENSLACP00000009303	Adhesion G protein-coupled receptor V1.	Myosin VI; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.	0.582
ADGRV1	OTOG	ENSLACP00000010057	ENSLACP00000017545	Adhesion G protein-coupled receptor V1.	Otogelin.	0.458
ADGRV1	OTOGL	ENSLACP00000010057	ENSLACP00000017922	Adhesion G protein-coupled receptor V1.	Otogelin like.	0.458
ADGRV1	PDZD7	ENSLACP00000010057	ENSLACP00000000972	Adhesion G protein-coupled receptor V1.	PDZ domain containing 7.	0.873
ADGRV1	SLC17A8	ENSLACP00000010057	ENSLACP00000019961	Adhesion G protein-coupled receptor V1.	Solute carrier family 17 member 8.	0.685
ADGRV1	TMC2	ENSLACP00000010057	ENSLACP00000004291	Adhesion G protein-coupled receptor V1.	Transmembrane channel-like protein.	0.431
ADGRV1	USH1C	ENSLACP00000010057	ENSLACP00000018193	Adhesion G protein-coupled receptor V1.	USH1 protein network component harmonin.	0.868
ADGRV1	USH1G	ENSLACP00000010057	ENSLACP00000012126	Adhesion G protein-coupled receptor V1.	USH1 protein network component sans.	0.690
ADGRV1	WFS1	ENSLACP00000010057	ENSLACP00000013099	Adhesion G protein-coupled receptor V1.	Wolframin ER transmembrane glycoprotein.	0.685
CDC14A	CDKN2D	ENSLACP00000015952	ENSLACP00000015676	Uncharacterized protein.	Cyclin dependent kinase inhibitor 2D.	0.593
CDKN2D	CDC14A	ENSLACP00000015676	ENSLACP00000015952	Cyclin dependent kinase inhibitor 2D.	Uncharacterized protein.	0.593
CFAP57	H2ZSI5_LATCH	ENSLACP00000002568	ENSLACP00000000356	Cilia and flagella associated protein 57.	Uncharacterized protein.	0.611
CLDN7	LOC102362960	ENSLACP00000009714	ENSLACP00000006965	Claudin 7b.	Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.	0.474
CLDN7	LOC102363509	ENSLACP00000009714	ENSLACP00000008554	Claudin 7b.	Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.	0.492