(47 nodes) Sensory perception of smell network (Latimeria chalumnae)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	H3A900_LATCH	Uncharacterized protein. (166 aa)
	H3A8D2_LATCH	G_PROTEIN_RECEP_F1_2 domain-containing protein. (365 aa)
	LOC102366831	Olfactory receptor. (311 aa)
	LOC102367600	Olfactory receptor. (319 aa)
	H3A6Z7_LATCH	Bardet-Biedl syndrome 1. (596 aa)
	H3A624_LATCH	Uncharacterized protein. (591 aa)
	CNGA4	Cyclic nucleotide gated channel subunit alpha 4. (533 aa)
	H3A458_LATCH	Vomeronasal type-1 receptor. (288 aa)
	LOC102346419	Olfactory receptor. (317 aa)
	LOC102351357	Olfactory receptor. (320 aa)
	LOC102366570	Olfactory receptor. (324 aa)
	LOC102364958	Olfactory receptor. (320 aa)
	SLC6A3	Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (624 aa)
	LOC102362379	G_PROTEIN_RECEP_F1_2 domain-containing protein. (319 aa)
	H2ZXP3_LATCH	Uncharacterized protein. (173 aa)
	BBS4	Bardet-Biedl syndrome 4. (537 aa)
	H2ZXG6_LATCH	Uncharacterized protein. (135 aa)
	H2ZWN0_LATCH	Reverse transcriptase domain-containing protein. (142 aa)
	LOC102345612	Olfactory receptor. (315 aa)
	LOC102363837	Olfactory receptor. (340 aa)
	TTC8	Tetratricopeptide repeat domain 8. (534 aa)
	LOC102358549	Vomeronasal type-1 receptor. (318 aa)
	DRD2	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (450 aa)
	H3BD69_LATCH	G_PROTEIN_RECEP_F1_2 domain-containing protein. (279 aa)
	H3BCB5_LATCH	Uncharacterized protein. (307 aa)
	GPR148	G_PROTEIN_RECEP_F1_2 domain-containing protein. (306 aa)
	H3B8L7_LATCH	Reverse transcriptase domain-containing protein. (526 aa)
	UBR3	E3 ubiquitin-protein ligase; Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N- terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation. (1851 aa)
	CNGA2	Cyclic nucleotide gated channel subunit alpha 2. (745 aa)
	ADCY3	Adenylate cyclase type 3; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1099 aa)
	LOC102349476	G_PROTEIN_RECEP_F1_2 domain-containing protein. (325 aa)
	NAV2	Neuron navigator 2a. (1109 aa)
	NXNL2	Nucleoredoxin like 2. (157 aa)
	OMP	Olfactory marker protein. (159 aa)
	LOC102346831	G_PROTEIN_RECEP_F1_2 domain-containing protein. (322 aa)
	H3AKY8_LATCH	Uncharacterized protein. (620 aa)
	H3AKA2_LATCH	G_PROTEIN_RECEP_F1_2 domain-containing protein. (333 aa)
	LOC102347675	Vomeronasal 2, receptor 1. (913 aa)
	H3AIN6_LATCH	G_PROTEIN_RECEP_F1_2 domain-containing protein. (345 aa)
	LOC102345801	Olfactory receptor. (321 aa)
	H3AH58_LATCH	Uncharacterized protein. (107 aa)
	H3AG29_LATCH	Uncharacterized protein. (600 aa)
	LOC102351278	Olfactory receptor. (308 aa)
	MKKS	McKusick-Kaufman syndrome. (575 aa)
	H3AA55_LATCH	Uncharacterized protein. (329 aa)
	LOC102367093	Olfactory receptor. (311 aa)
	H3A992_LATCH	Olfactory receptor. (330 aa)

Your Current Organism:

Latimeria chalumnae

NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ADCY3	CNGA2	ENSLACP00000015140	ENSLACP00000015947	Adenylate cyclase type 3; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Cyclic nucleotide gated channel subunit alpha 2.	0.726
ADCY3	CNGA4	ENSLACP00000015140	ENSLACP00000004899	Adenylate cyclase type 3; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Cyclic nucleotide gated channel subunit alpha 4.	0.401
BBS4	H3A6Z7_LATCH	ENSLACP00000002102	ENSLACP00000005418	Bardet-Biedl syndrome 4.	Bardet-Biedl syndrome 1.	0.998
BBS4	TTC8	ENSLACP00000002102	ENSLACP00000022744	Bardet-Biedl syndrome 4.	Tetratricopeptide repeat domain 8.	0.997
CNGA2	ADCY3	ENSLACP00000015947	ENSLACP00000015140	Cyclic nucleotide gated channel subunit alpha 2.	Adenylate cyclase type 3; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.726
CNGA2	CNGA4	ENSLACP00000015947	ENSLACP00000004899	Cyclic nucleotide gated channel subunit alpha 2.	Cyclic nucleotide gated channel subunit alpha 4.	0.949
CNGA2	OMP	ENSLACP00000015947	ENSLACP00000011246	Cyclic nucleotide gated channel subunit alpha 2.	Olfactory marker protein.	0.627
CNGA4	ADCY3	ENSLACP00000004899	ENSLACP00000015140	Cyclic nucleotide gated channel subunit alpha 4.	Adenylate cyclase type 3; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.401
CNGA4	CNGA2	ENSLACP00000004899	ENSLACP00000015947	Cyclic nucleotide gated channel subunit alpha 4.	Cyclic nucleotide gated channel subunit alpha 2.	0.949
DRD2	SLC6A3	ENSLACP00000020922	ENSLACP00000002580	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family.	Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.	0.727
H3A6Z7_LATCH	BBS4	ENSLACP00000005418	ENSLACP00000002102	Bardet-Biedl syndrome 1.	Bardet-Biedl syndrome 4.	0.998
H3A6Z7_LATCH	MKKS	ENSLACP00000005418	ENSLACP00000006659	Bardet-Biedl syndrome 1.	McKusick-Kaufman syndrome.	0.444
H3A6Z7_LATCH	TTC8	ENSLACP00000005418	ENSLACP00000022744	Bardet-Biedl syndrome 1.	Tetratricopeptide repeat domain 8.	0.998
MKKS	H3A6Z7_LATCH	ENSLACP00000006659	ENSLACP00000005418	McKusick-Kaufman syndrome.	Bardet-Biedl syndrome 1.	0.444
OMP	CNGA2	ENSLACP00000011246	ENSLACP00000015947	Olfactory marker protein.	Cyclic nucleotide gated channel subunit alpha 2.	0.627
SLC6A3	DRD2	ENSLACP00000002580	ENSLACP00000020922	Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family.	0.727
TTC8	BBS4	ENSLACP00000022744	ENSLACP00000002102	Tetratricopeptide repeat domain 8.	Bardet-Biedl syndrome 4.	0.997
TTC8	H3A6Z7_LATCH	ENSLACP00000022744	ENSLACP00000005418	Tetratricopeptide repeat domain 8.	Bardet-Biedl syndrome 1.	0.998