(16 nodes) Motor neuron axon guidance network (Latimeria chalumnae)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	RNF165	Ring finger protein 165. (351 aa)
	MYCBP2	MYC binding protein 2. (5051 aa)
	LOC102356949	Netrin 2. (513 aa)
	SEMA3F	Semaphorin 3F; Belongs to the semaphorin family. (772 aa)
	SLIT1	Slit guidance ligand 1. (925 aa)
	H3AC70_LATCH	LRRNT domain-containing protein. (132 aa)
	NTN1	Netrin 1. (604 aa)
	LOC102346244	Uncharacterized protein. (567 aa)
	CDK5	Cyclin dependent kinase 5. (290 aa)
	LHX4	LIM homeobox 4. (312 aa)
	SLIT2	Slit guidance ligand 2. (1372 aa)
	RHOH	Ras homolog family member H. (189 aa)
	LOC102362077	Ras homolog gene family, member Gc. (192 aa)
	RHOG	Ras homolog family member G. (191 aa)
	LHX3	LIM homeobox 3. (313 aa)
	LAMC2	Uncharacterized protein. (1189 aa)

Your Current Organism:

Latimeria chalumnae

NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
H3AC70_LATCH	SLIT1	ENSLACP00000007241	ENSLACP00000006092	LRRNT domain-containing protein.	Slit guidance ligand 1.	0.908
H3AC70_LATCH	SLIT2	ENSLACP00000007241	ENSLACP00000012299	LRRNT domain-containing protein.	Slit guidance ligand 2.	0.900
LOC102346244	SLIT1	ENSLACP00000008799	ENSLACP00000006092	Uncharacterized protein.	Slit guidance ligand 1.	0.719
LOC102356949	SLIT1	ENSLACP00000005653	ENSLACP00000006092	Netrin 2.	Slit guidance ligand 1.	0.719
LOC102362077	RHOG	ENSLACP00000013451	ENSLACP00000014649	Ras homolog gene family, member Gc.	Ras homolog family member G.	0.901
NTN1	SLIT1	ENSLACP00000007761	ENSLACP00000006092	Netrin 1.	Slit guidance ligand 1.	0.698
RHOG	LOC102362077	ENSLACP00000014649	ENSLACP00000013451	Ras homolog family member G.	Ras homolog gene family, member Gc.	0.901
SEMA3F	SLIT1	ENSLACP00000005773	ENSLACP00000006092	Semaphorin 3F; Belongs to the semaphorin family.	Slit guidance ligand 1.	0.559
SLIT1	H3AC70_LATCH	ENSLACP00000006092	ENSLACP00000007241	Slit guidance ligand 1.	LRRNT domain-containing protein.	0.908
SLIT1	LOC102346244	ENSLACP00000006092	ENSLACP00000008799	Slit guidance ligand 1.	Uncharacterized protein.	0.719
SLIT1	LOC102356949	ENSLACP00000006092	ENSLACP00000005653	Slit guidance ligand 1.	Netrin 2.	0.719
SLIT1	NTN1	ENSLACP00000006092	ENSLACP00000007761	Slit guidance ligand 1.	Netrin 1.	0.698
SLIT1	SEMA3F	ENSLACP00000006092	ENSLACP00000005773	Slit guidance ligand 1.	Semaphorin 3F; Belongs to the semaphorin family.	0.559
SLIT2	H3AC70_LATCH	ENSLACP00000012299	ENSLACP00000007241	Slit guidance ligand 2.	LRRNT domain-containing protein.	0.900