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| | ACSL1 | Acyl-CoA synthetase long chain family member 1. (702 aa) |
| | ATP5F1A | ATP synthase subunit alpha; Produces ATP from ADP in the presence of a proton gradient across the membrane. (553 aa) |
| | UMPS | Uridine monophosphate synthetase. (290 aa) |
| | LOC106702268 | Uncharacterized protein. (107 aa) |
| | H2ZS04_LATCH | Guanylate cyclase. (828 aa) |
| | TK2 | Thymidine kinase 2. (233 aa) |
| | TBPL1 | TATA-box binding protein like 1. (124 aa) |
| | LOC102359008 | Uncharacterized protein. (1519 aa) |
| | LOC102363111 | AMP-binding_C domain-containing protein. (185 aa) |
| | LOC102351936 | Guanylate cyclase domain-containing protein. (203 aa) |
| | H2ZTP3_LATCH | Guanylate cyclase domain-containing protein. (178 aa) |
| | LOC102351310 | Adenine phosphoribosyltransferase. (119 aa) |
| | ASPDH | Aspartate dehydrogenase domain containing. (285 aa) |
| | PAPSS1 | 3'-phosphoadenosine 5'-phosphosulfate synthase 1. (603 aa) |
| | AK4 | Adenylate kinase 4, mitochondrial; Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Efficiently phosphorylates AMP and dAMP using ATP as phosphate donor, but phosphorylates only AMP when using GTP as phosphate donor. Also displays broad nucleoside diphosphate kinase activity. (229 aa) |
| | HAAO | Uncharacterized protein. (252 aa) |
| | DCAKD | Dephospho-CoA kinase domain containing. (244 aa) |
| | LOC102347240 | Pribosyltran_N domain-containing protein. (322 aa) |
| | LOC102352017 | Zgc:174895. (223 aa) |
| | ADSS1 | Adenylosuccinate synthetase isozyme 1; Component of the purine nucleotide cycle (PNC), which interconverts IMP and AMP to regulate the nucleotide levels in various tissues, and which contributes to glycolysis and ammoniagenesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. (449 aa) |
| | ELOVL4 | Elongation of very long chain fatty acids protein. (292 aa) |
| | RFK | Riboflavin kinase. (155 aa) |
| | QPRT | Nicotinate-nucleotide pyrophosphorylase [carboxylating]; Involved in the catabolism of quinolinic acid (QA). Belongs to the NadC/ModD family. (324 aa) |
| | ADSL | Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. (500 aa) |
| | ELOVL1 | Elongation of very long chain fatty acids protein 1; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that exhibits activity toward saturated C18 to C26 acyl-CoA substrates, with the highest activity towards C22:0 acyl-CoA. May participate to the production of both saturated and monounsaturated VLCFAs of different chain lengths that [...] (302 aa) |
| | ACAT1 | Acetyl-CoA acetyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family. (422 aa) |
| | AMPD2 | AMP deaminase; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. (823 aa) |
| | UPP1 | Uridine phosphorylase; Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis. (313 aa) |
| | GARS1 | Glycyl-tRNA synthetase. (520 aa) |
| | ACSL4 | Acyl-CoA synthetase long chain family member 4. (713 aa) |
| | IDO2 | Indoleamine 2,3-dioxygenase 1. (425 aa) |
| | ACLY | ATP citrate lyase. (978 aa) |
| | DTYMK | Deoxythymidylate kinase. (189 aa) |
| | LOC102346876 | Elongation of very long chain fatty acids protein. (265 aa) |
| | LOC102355337 | Zgc:110540. (270 aa) |
| | IMPDH2 | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. (524 aa) |
| | ATIC | 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase. (594 aa) |
| | ADCY4 | Adenylate cyclase type 4; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1092 aa) |
| | PPAT | Amidophosphoribosyltransferase; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. (444 aa) |
| | PRPS1 | Pribosyltran_N domain-containing protein. (339 aa) |
| | SLC25A13 | Solute carrier family 25 member 13; Belongs to the mitochondrial carrier (TC 2.A.29) family. (682 aa) |
| | UCKL1 | Uridine-cytidine kinase 1 like 1. (550 aa) |
| | NAMPT | Nicotinamide phosphoribosyltransferase; Belongs to the NAPRTase family. (492 aa) |
| | DGUOK | Deoxyguanosine kinase. (286 aa) |
| | LOC106704948 | Uncharacterized protein; Belongs to the adenylate kinase family. (552 aa) |
| | AK3 | GTP:AMP phosphotransferase AK3, mitochondrial; Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Has GTP:AMP phosphotransferase and ITP:AMP phosphotransferase activities. (227 aa) |
| | GUCY2F | Guanylate cyclase. (1115 aa) |
| | PAICS | AIRC domain-containing protein. (1029 aa) |
| | PANK2 | Pantothenate kinase 2. (368 aa) |
| | NMNAT1 | Nicotinamide-nucleotide adenylyltransferase. (286 aa) |
| | H3A8S5_LATCH | Nicotinate phosphoribosyltransferase. (581 aa) |
| | LOC102350392 | Hypoxanthine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. (214 aa) |
| | ATP5J | ATP synthase-coupling factor 6, mitochondrial; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain; Belongs to the eukaryotic ATPase subunit F6 family. (110 aa) |
| | NME6 | Nucleoside diphosphate kinase. (188 aa) |
| | NME1 | Nucleoside diphosphate kinase. (172 aa) |
| | LOC102351204 | DUF1053 domain-containing protein. (254 aa) |
| | ADCY5-2 | AC_N domain-containing protein. (323 aa) |
| | ACSL6 | Uncharacterized protein. (749 aa) |
| | ELOVL5 | Elongation of very long chain fatty acids protein. (219 aa) |
| | NPR1 | Guanylate cyclase. (1062 aa) |
| | H3AB00_LATCH | ANF_receptor domain-containing protein. (223 aa) |
| | H3AB06_LATCH | Guanylate cyclase domain-containing protein. (1528 aa) |
| | UCK2 | Uridine-cytidine kinase 2. (180 aa) |
| | GUCY1A1 | Guanylate cyclase 1 soluble subunit alpha 1; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1298 aa) |
| | ADCY7 | Adenylate cyclase type 7; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1047 aa) |
| | ELOVL2 | Elongation of very long chain fatty acids protein 2; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Acts specifically toward polyunsaturated acyl-CoA with the higher activity toward C20:4(n-6) acyl-CoA. Condensing enzyme that catalyzes the synthesis of polyunsaturated very long chain fatty acid (C20- and C22-PUFA). May participate to the production [...] (266 aa) |
| | KARS1 | Lysine--tRNA ligase. (618 aa) |
| | NMNAT3 | Nicotinamide-nucleotide adenylyltransferase. (290 aa) |
| | ADCY9 | Adenylate cyclase 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1340 aa) |
| | PPCDC | Phosphopantothenoylcysteine decarboxylase. (214 aa) |
| | ATP5MC3 | ATP synthase membrane subunit c locus 3; Belongs to the ATPase C chain family. (143 aa) |
| | H3AE67_LATCH | Si:ch211-215j19.12; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (252 aa) |
| | PANK1 | Pantothenate kinase 1. (370 aa) |
| | COASY | Coenzyme A synthase. (544 aa) |
| | H3AF20_LATCH | Si:ch211-243j20.2. (511 aa) |
| | H3AFH5_LATCH | Guanylate cyclase. (817 aa) |
| | NMNAT2 | Nicotinamide nucleotide adenylyltransferase 2. (202 aa) |
| | GMPS | Guanine monophosphate synthase. (683 aa) |
| | AK5 | Adenylate kinase 5; Belongs to the adenylate kinase family. (296 aa) |
| | PAPSS2 | 3'-phosphoadenosine 5'-phosphosulfate synthase 2. (619 aa) |
| | ADCY5 | Adenylate cyclase 5; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (824 aa) |
| | LOC106703556 | Natriuretic peptide A-like. (129 aa) |
| | KMO | Kynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid. (474 aa) |
| | LOC102364365 | Natriuretic peptide A-like. (130 aa) |
| | RRM1 | Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. (763 aa) |
| | IMPDH1 | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. (515 aa) |
| | PFAS | Phosphoribosylformylglycinamidine synthase. (1082 aa) |
| | ATP6V1A | ATPase H+ transporting V1 subunit A. (617 aa) |
| | ATP5F1C | ATP synthase F1 subunit gamma. (493 aa) |
| | H3AKY9_LATCH | Uncharacterized protein. (111 aa) |
| | CMPK2 | Cytidine/uridine monophosphate kinase 2. (381 aa) |
| | ATP5F1B | ATP synthase subunit beta; Produces ATP from ADP in the presence of a proton gradient across the membrane. (312 aa) |
| | LOC102358088 | Guanylate cyclase domain-containing protein; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (663 aa) |
| | H3AMS8_LATCH | Uncharacterized protein; Belongs to the adenylate kinase family. (171 aa) |
| | ATP5F1D | ATP synthase F1 subunit delta. (166 aa) |
| | AK9 | Adenylate kinase 9. (1928 aa) |
| | STOML2 | Stomatin like 2. (294 aa) |
| | PRTFDC1 | Hypoxanthine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. (226 aa) |
| | H3ANZ2_LATCH | Uncharacterized protein. (440 aa) |
| | LOC102351946 | Guanylate cyclase. (1068 aa) |
| | CMPK1 | UMP-CMP kinase; Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and CMP as phosphate acceptors. Also displays broad nucleoside diphosphate kinase activity; Belongs to the adenylate kinase family. UMP-CMP kinase subfamily. (213 aa) |
| | DMAC2L | Distal membrane arm assembly complex 2 like. (199 aa) |
| | ADCY8 | AC_N domain-containing protein. (266 aa) |
| | PDHX | Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex. (534 aa) |
| | GUCY2D | Guanylate cyclase. (1026 aa) |
| | PRPSAP2 | Phosphoribosyl pyrophosphate synthetase associated protein 2. (357 aa) |
| | H3AQU6_LATCH | AC_N domain-containing protein. (191 aa) |
| | LOC102361881 | Guanylate cyclase domain-containing protein; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (612 aa) |
| | ADSS2 | Adenylosuccinate synthetase; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. (460 aa) |
| | DCK | Deoxycytidine kinase. (263 aa) |
| | PPCS | Phosphopantothenoylcysteine synthetase. (331 aa) |
| | PDHA1 | Pyruvate dehydrogenase E1 component subunit alpha; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (400 aa) |
| | AK6 | Adenylate kinase isoenzyme 6; Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates. May have a role in nuclear energy homeostasis. Has also ATPase activity. May be involved in regulation of Cajal body (CB) formation; Belongs to the adenylate kinase family. AK6 subfamily. (174 aa) |
| | NDUFB2 | NADH:ubiquinone oxidoreductase subunit B2. (101 aa) |
| | ATP5MF | Uncharacterized protein. (89 aa) |
| | ACSL5 | Acyl-CoA synthetase long chain family member 5. (683 aa) |
| | GCDH | Glutaryl-CoA dehydrogenase. (437 aa) |
| | GUK1 | Guanylate kinase 1. (210 aa) |
| | NMRK1 | Nicotinamide riboside kinase 1. (212 aa) |
| | MPC2 | Mitochondrial pyruvate carrier; Mediates the uptake of pyruvate into mitochondria. Belongs to the mitochondrial pyruvate carrier (MPC) (TC 2.A.105) family. (131 aa) |
| | NADK2 | NAD kinase 2, mitochondrial; Mitochondrial NAD(+) kinase that phosphorylates NAD(+) to yield NADP(+). Can use both ATP or inorganic polyphosphate as the phosphoryl donor. (427 aa) |
| | ATP5PO | ATP synthase peripheral stalk subunit OSCP. (184 aa) |
| | RRM2 | Ribonucleotide reductase regulatory subunit M2. (389 aa) |
| | LRGUK | Leucine rich repeats and guanylate kinase domain containing. (595 aa) |
| | FCSK | Fucose kinase. (956 aa) |
| | ATP5MC2 | ATP synthase membrane subunit c locus 2; Belongs to the ATPase C chain family. (140 aa) |
| | FLAD1 | Flavin adenine dinucleotide synthetase 1. (523 aa) |
| | ACACB | Acetyl-CoA carboxylase beta. (2311 aa) |
| | ACSS1 | Acetyl-coenzyme A synthetase. (645 aa) |
| | GUCY2C | Guanylate cyclase. (685 aa) |
| | PDHB | Pyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. (393 aa) |
| | MLYCD | Malonyl-CoA decarboxylase. (480 aa) |
| | H3AWZ8_LATCH | Uncharacterized protein. (385 aa) |
| | LOC102364477 | AMP-binding domain-containing protein. (704 aa) |
| | HTD2 | Hydroxyacyl-thioester dehydratase type 2. (235 aa) |
| | H3AYB6_LATCH | Uncharacterized protein. (401 aa) |
| | NME3 | NME/NM23 nucleoside diphosphate kinase 3; Belongs to the NDK family. (131 aa) |
| | ADCY3 | Adenylate cyclase type 3; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1099 aa) |
| | ELOVL7 | Elongation of very long chain fatty acids protein. (272 aa) |
| | CTPS1 | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. (594 aa) |
| | NME7 | Nucleoside diphosphate kinase 7; Belongs to the NDK family. (376 aa) |
| | NME5 | NME/NM23 family member 5; Belongs to the NDK family. (270 aa) |
| | DCTD | dCMP deaminase. (202 aa) |
| | GUCD1 | Guanylyl cyclase domain containing 1. (236 aa) |
| | H3B661_LATCH | Elongation of very long chain fatty acids protein. (265 aa) |
| | LOC102360556 | NAD kinase b. (400 aa) |
| | NADSYN1 | Glutamine-dependent NAD(+) synthetase; In the C-terminal section; belongs to the NAD synthetase family. (706 aa) |
| | DLAT | Acetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (629 aa) |
| | LOC102359843 | Guanylate cyclase domain-containing protein. (611 aa) |
| | H3B7J3_LATCH | Guanylate cyclase. (822 aa) |
| | TK1 | Thymidine kinase. (239 aa) |
| | PANK4 | Pantothenate kinase 4; Belongs to the type II pantothenate kinase family. (780 aa) |
| | TYMS | Thymidylate synthetase. (309 aa) |
| | ATP5MC1 | ATP synthase membrane subunit c locus 1; Belongs to the ATPase C chain family. (139 aa) |
| | PRPSAP1 | Phosphoribosyl pyrophosphate synthetase associated protein 1. (290 aa) |
| | LOC102356272 | Lysine--tRNA ligase. (511 aa) |
| | PANK3 | Pantothenate kinase 3. (370 aa) |
| | H3BAZ9_LATCH | Adenylate kinase 5, like; Belongs to the adenylate kinase family. (437 aa) |
| | AK1 | Adenylate kinase isoenzyme 1; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Also displays broad nucleoside diphosphate kinase activity. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism. (211 aa) |
| | ACOT7 | Acyl-CoA thioesterase 7. (318 aa) |
| | ADCY6 | Adenylate cyclase 6; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (894 aa) |
| | LOC102349899 | Guanylate cyclase domain-containing protein; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (657 aa) |
| | HPRT1 | Hypoxanthine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. (180 aa) |
| | UCK1 | Uridine-cytidine kinase; Belongs to the uridine kinase family. (270 aa) |
| | LOC102345276 | Adenylosuccinate synthetase; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. (405 aa) |
| | AFMID | Kynurenine formamidase; Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation. Kynurenine may be further oxidized to nicotinic acid, NAD(H) and NADP(H). Required for elimination of toxic metabolites. (293 aa) |
| | NME4 | Nucleoside diphosphate kinase. (166 aa) |
| | LOC102358019 | Uncharacterized protein. (83 aa) |
| | TGFB1 | Transforming growth factor beta; Belongs to the TGF-beta family. (401 aa) |
| | ACACA | Acetyl-CoA carboxylase alpha. (2312 aa) |
| | AMPD3 | AMP deaminase; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. (773 aa) |
| | AK7 | Adenylate kinase 7. (711 aa) |
| | ATP5MG | ATP synthase subunit; Mitochondrial membrane ATP synthase (F1F0 ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F1 - containing the extramembraneous catalytic core, and F0 - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F1 is coupled via a rotary mechanism of the central stalk subunits to proto [...] (107 aa) |
| | AMPD1 | AMP deaminase; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. (706 aa) |
| | ACSS2 | Acyl-CoA synthetase short chain family member 2. (687 aa) |
| | LOC102349787 | Uncharacterized protein. (91 aa) |
| | LOC102357659 | Uncharacterized protein. (518 aa) |
| | ATP5PB | ATP synthase peripheral stalk-membrane subunit b. (250 aa) |
| | NADK | NAD kinase. (308 aa) |
| | ATP6 | ATP synthase subunit a; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subuni [...] (220 aa) |
| | ATP5PD | ATP synthase subunit d, mitochondrial; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the cent [...] (161 aa) |
| | GART | Trifunctional purine biosynthetic protein adenosine-3; In the C-terminal section; belongs to the GART family. In the central section; belongs to the AIR synthase family. (1031 aa) |
| | ADK | Adenosine kinase. (302 aa) |
| | CDA | Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family. (145 aa) |
| | AK2 | Adenylate kinase 2; Belongs to the adenylate kinase family. (217 aa) |
| | SYNPR-2 | Nicotinamide phosphoribosyltransferase; Belongs to the NAPRTase family. (493 aa) |
| | KYNU | Kynureninase. (278 aa) |
| | ELOVL6 | Elongation of very long chain fatty acids protein 6; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that elongates fatty acids with 12, 14 and 16 carbons with higher activity toward C16:0 acyl-CoAs. Catalyzes the synthesis of unsaturated C16 long chain fatty acids and, to a lesser extent, C18:0 and those with low desaturation degre [...] (265 aa) |
| | ATP8 | ATP synthase protein 8; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subuni [...] (55 aa) |
