13 items (Latimeria chalumnae) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	PNPO	Pyridoxamine 5'-phosphate oxidase. (257 aa)
	NOS1	Nitric oxide synthase 1. (1476 aa)
	NDOR1	NADPH-dependent diflavin oxidoreductase 1; Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery. Required for the maturation of extramitochondrial Fe-S proteins. Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis. Transfers electrons from NADPH to the Fe/S cluster of CIAPIN1. In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family. (597 aa)
	NOS2	Nitric oxide synthase; Produces nitric oxide (NO). (1126 aa)
	POR	NADPH--cytochrome P450 reductase; This enzyme is required for electron transfer from NADP to cytochrome P450 in microsomes. It can also provide electron transfer to heme oxygenase and cytochrome B5; In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family. (676 aa)
	TYW1	tRNA-yW synthesizing protein 1 homolog (S. cerevisiae). (759 aa)
	PPCDC	Phosphopantothenoylcysteine decarboxylase. (214 aa)
	NDUFV1	NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. (475 aa)
	IYD	Iodotyrosine deiodinase. (235 aa)
	DUS2	Dihydrouridine synthase 2. (484 aa)
	HAO1	Hydroxyacid oxidase 1. (370 aa)
	HAO2	Hydroxyacid oxidase 2. (356 aa)
	MTRR	5-methyltetrahydrofolate-homocysteine methyltransferase reductase. (720 aa)

Your Current Organism:

Latimeria chalumnae

NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
HAO1	HAO2	ENSLACP00000005585	ENSLACP00000011074	Hydroxyacid oxidase 1.	Hydroxyacid oxidase 2.	0.920
HAO2	HAO1	ENSLACP00000011074	ENSLACP00000005585	Hydroxyacid oxidase 2.	Hydroxyacid oxidase 1.	0.920
IYD	NDUFV1	ENSLACP00000000866	ENSLACP00000007611	Iodotyrosine deiodinase.	NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain.	0.504
IYD	PNPO	ENSLACP00000000866	ENSLACP00000007984	Iodotyrosine deiodinase.	Pyridoxamine 5'-phosphate oxidase.	0.446
NDUFV1	IYD	ENSLACP00000007611	ENSLACP00000000866	NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain.	Iodotyrosine deiodinase.	0.504
NOS1	NOS2	ENSLACP00000007966	ENSLACP00000020145	Nitric oxide synthase 1.	Nitric oxide synthase; Produces nitric oxide (NO).	0.902
NOS2	NOS1	ENSLACP00000020145	ENSLACP00000007966	Nitric oxide synthase; Produces nitric oxide (NO).	Nitric oxide synthase 1.	0.902
PNPO	IYD	ENSLACP00000007984	ENSLACP00000000866	Pyridoxamine 5'-phosphate oxidase.	Iodotyrosine deiodinase.	0.446