STRINGSTRING
H3BE69_LATCH H3BE69_LATCH BCL9L BCL9L LOC102352268 LOC102352268 LRG1 LRG1 TGFB3 TGFB3 MTOR MTOR H3B8U3_LATCH H3B8U3_LATCH ENG ENG LOC102358988 LOC102358988 BMP4 BMP4 JAG1 JAG1 CTNNB1 CTNNB1 BMP2 BMP2 DAB2 DAB2 H3AVL9_LATCH H3AVL9_LATCH RGCC RGCC LOXL2 LOXL2 TBX20 TBX20 SMAD3 SMAD3 ACVR1 ACVR1 IL6 IL6 SMAD4 SMAD4 LOC102351081 LOC102351081 SMAD2 SMAD2 TGFBR1 TGFBR1 BAMBI BAMBI TGFB2 TGFB2 LEF1 LEF1 TGFBR2 TGFBR2 GLIPR2 GLIPR2 MDK MDK TGFB1 TGFB1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
H3BE69_LATCHPID domain-containing protein. (136 aa)
BCL9LBCL9 like. (1514 aa)
LOC102352268Transforming growth factor beta; Belongs to the TGF-beta family. (414 aa)
LRG1LRRCT domain-containing protein. (337 aa)
TGFB3Transforming growth factor beta; Belongs to the TGF-beta family. (409 aa)
MTORMechanistic target of rapamycin kinase; Belongs to the PI3/PI4-kinase family. (1009 aa)
H3B8U3_LATCHSerine/threonine-protein kinase TOR. (1418 aa)
ENGEndoglin. (674 aa)
LOC102358988Mothers against decapentaplegic homolog. (614 aa)
BMP4Bone morphogenetic protein 4. (460 aa)
JAG1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1220 aa)
CTNNB1Catenin beta 1. (781 aa)
BMP2Bone morphogenetic protein 2. (402 aa)
DAB2DAB adaptor protein 2. (745 aa)
H3AVL9_LATCHLysyl oxidase-like 3b. (475 aa)
RGCCRegulator of cell cycle. (127 aa)
LOXL2Lysyl oxidase like 2. (773 aa)
TBX20T-box transcription factor 20. (441 aa)
SMAD3Mothers against decapentaplegic homolog. (358 aa)
ACVR1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (506 aa)
IL6Uncharacterized protein. (149 aa)
SMAD4MH2 domain-containing protein. (412 aa)
LOC102351081Bone morphogenetic protein 16. (396 aa)
SMAD2Mothers against decapentaplegic homolog. (467 aa)
TGFBR1Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (507 aa)
BAMBIBMP and activin membrane-bound inhibitor homolog; Negatively regulates TGF-beta signaling. Belongs to the BAMBI family. (259 aa)
TGFB2Transforming growth factor beta; Belongs to the TGF-beta family. (415 aa)
LEF1Lymphoid enhancer binding factor 1. (397 aa)
TGFBR2TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (585 aa)
GLIPR2GLI pathogenesis related 2; Belongs to the CRISP family. (153 aa)
MDKMidkine. (141 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (401 aa)
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
Server load: medium (46%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.