STRINGSTRING
GOLGA4 GOLGA4 NRP1 NRP1 TNFRSF1B TNFRSF1B LOC102350310 LOC102350310 LOC102347127 LOC102347127 NUMB NUMB VEGFC VEGFC LOC102366586 LOC102366586 MAP6 MAP6 RELN RELN C1QBP C1QBP LOC102365550 LOC102365550 TP73 TP73 LAYN LAYN NUMBL NUMBL PLXNA2 PLXNA2 DIXDC1 DIXDC1 MDK MDK NGF NGF DRD2 DRD2 TGFB1 TGFB1 WNT2B WNT2B H3BF46_LATCH H3BF46_LATCH H3BF33_LATCH H3BF33_LATCH H3BEX6_LATCH H3BEX6_LATCH H3BE69_LATCH H3BE69_LATCH LOC102365809 LOC102365809 BNC1 BNC1 ZNF335 ZNF335 WNT3A WNT3A IL1RAPL2 IL1RAPL2 LOC102346019 LOC102346019 AMIGO1 AMIGO1 DMTN DMTN DBNL DBNL SOX8 SOX8 MTOR MTOR CIB1 CIB1 H3BA69_LATCH H3BA69_LATCH EFNA5 EFNA5 NEFL NEFL CASS4 CASS4 DHX36 DHX36 H3B938_LATCH H3B938_LATCH LIMS2 LIMS2 H3B8U3_LATCH H3B8U3_LATCH NPTN NPTN CDC42 CDC42 WNT2 WNT2 CYFIP1 CYFIP1 NEURL1 NEURL1 NR2E1 NR2E1 H3B780_LATCH H3B780_LATCH OTP OTP JADE2 JADE2 H3B6N2_LATCH H3B6N2_LATCH PAX6 PAX6 PTN PTN CLDN5 CLDN5 PLXNB2 PLXNB2 CTNNB1 CTNNB1 BMPR2 BMPR2 BAIAP2 BAIAP2 H3B4Z7_LATCH H3B4Z7_LATCH MYOG MYOG METRN METRN SLC7A5 SLC7A5 H3B3V9_LATCH H3B3V9_LATCH MAPT MAPT MYOD1 MYOD1 CUX2 CUX2 SRF SRF DBN1 DBN1 LOC102360711 LOC102360711 ANAPC2 ANAPC2 H3B181_LATCH H3B181_LATCH GFAP GFAP SNW1 SNW1 TESK1 TESK1 C1QTNF9 C1QTNF9 CRKL CRKL DAB2 DAB2 FOXG1 FOXG1 ADD1 ADD1 ALCAM ALCAM FAIM FAIM PLXND1 PLXND1 TIAM1 TIAM1 STK11 STK11 BDNF BDNF FZD3 FZD3 MECP2 MECP2 BRAF BRAF CDH5 CDH5 LRRC45 LRRC45 NKX6-1 NKX6-1 TIAM2 TIAM2 MYF6 MYF6 LOC102347877 LOC102347877 CRK CRK SHTN1 SHTN1 RND2 RND2 DCT DCT BAD BAD LOC102357614 LOC102357614 MYOC MYOC LOC102366200 LOC102366200 ANKRD27 ANKRD27 ADNP ADNP UFL1 UFL1 H3AM01_LATCH H3AM01_LATCH RREB1 RREB1 IL6ST IL6ST LIMS1 LIMS1 LOC102350832 LOC102350832 LOC102358409 LOC102358409 CDKL5 CDKL5 IL6 IL6 TNFSF11 TNFSF11 H3AHE4_LATCH H3AHE4_LATCH RUFY3 RUFY3 GSX2 GSX2 WNT3 WNT3 KDM1A KDM1A LOC102363869 LOC102363869 H3AEV1_LATCH H3AEV1_LATCH GPER1 GPER1 NKX6-2 NKX6-2 LTA LTA CAPRIN2 CAPRIN2 PLXNA3 PLXNA3 XRCC5 XRCC5 LOC102360373 LOC102360373 ILK ILK SYNJ1 SYNJ1 SMAD7 SMAD7 LYN LYN PLXNA1 PLXNA1 ISLR ISLR AMIGO3 AMIGO3 H3A8K8_LATCH H3A8K8_LATCH FN1 FN1 MAG MAG SERPINE2 SERPINE2 IL1RAPL1 IL1RAPL1 RET RET SHANK3 SHANK3 LOC102366847 LOC102366847 LOC102356309 LOC102356309 GLI3 GLI3 LOC102363099 LOC102363099 SEMA4D SEMA4D ITPKA ITPKA H3A2T1_LATCH H3A2T1_LATCH LOC102356030 LOC102356030 H3A2E1_LATCH H3A2E1_LATCH CAPRIN1 CAPRIN1 XRCC2 XRCC2 LIG4 LIG4 SPEN SPEN OPRD1 OPRD1 NTRK2 NTRK2 PLXNB1 PLXNB1 PLXNA3-2 PLXNA3-2 H2ZZI1_LATCH H2ZZI1_LATCH IST1 IST1 SMO SMO SLITRK1 SLITRK1 TRIM32 TRIM32 SERPINF1 SERPINF1 NEDD9 NEDD9 MYADM MYADM EEF2K EEF2K PTPRZ1 PTPRZ1 TRAK1 TRAK1 CHODL CHODL LOC102364341 LOC102364341 SRRT SRRT CLCF1 CLCF1 LOC102347948 LOC102347948 TRIOBP TRIOBP ASPA ASPA ZFYVE27 ZFYVE27 ADIPOQ ADIPOQ H2ZS97_LATCH H2ZS97_LATCH
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
GOLGA4Golgin A4. (2330 aa)
NRP1Neuropilin; Belongs to the neuropilin family. (928 aa)
TNFRSF1BTNF receptor superfamily member 1B. (465 aa)
LOC102350310GBP domain-containing protein. (339 aa)
LOC102347127ADF-H domain-containing protein. (892 aa)
NUMBNUMB endocytic adaptor protein. (659 aa)
VEGFCVascular endothelial growth factor C; Belongs to the PDGF/VEGF growth factor family. (410 aa)
LOC102366586Sema domain-containing protein; Belongs to the semaphorin family. (620 aa)
MAP6Microtubule-associated protein 6a. (300 aa)
RELNReelin. (3462 aa)
C1QBPComplement C1q binding protein. (335 aa)
LOC102365550Uncharacterized protein. (218 aa)
TP73Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (636 aa)
LAYNLayilin. (375 aa)
NUMBLNUMB like endocytic adaptor protein. (590 aa)
PLXNA2Plexin A2. (1897 aa)
DIXDC1DIX domain containing 1. (695 aa)
MDKMidkine. (141 aa)
NGFNerve growth factor; Belongs to the NGF-beta family. (272 aa)
DRD2G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (450 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (401 aa)
WNT2BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (370 aa)
H3BF46_LATCHOlfactomedin-like domain-containing protein. (462 aa)
H3BF33_LATCHOlfactomedin-like domain-containing protein. (464 aa)
H3BEX6_LATCHReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (307 aa)
H3BE69_LATCHPID domain-containing protein. (136 aa)
LOC102365809Si:ch211-113g11.6; Belongs to the semaphorin family. (631 aa)
BNC1Basonuclin 1. (951 aa)
ZNF335Zinc finger protein 335. (1379 aa)
WNT3AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (367 aa)
IL1RAPL2Interleukin 1 receptor accessory protein-like 2. (429 aa)
LOC102346019C1q domain-containing protein. (226 aa)
AMIGO1Adhesion molecule with Ig like domain 1. (506 aa)
DMTNDematin actin binding protein. (406 aa)
DBNLDrebrin like. (512 aa)
SOX8SRY-box transcription factor 8. (477 aa)
MTORMechanistic target of rapamycin kinase; Belongs to the PI3/PI4-kinase family. (1009 aa)
CIB1Calcium and integrin binding 1. (190 aa)
H3BA69_LATCHSi:ch73-330k17.3. (196 aa)
EFNA5Ephrin A5; Belongs to the ephrin family. (185 aa)
NEFLNeurofilament light; Belongs to the intermediate filament family. (555 aa)
CASS4Cas scaffold protein family member 4. (817 aa)
DHX36DEAH-box helicase 36. (1001 aa)
H3B938_LATCHTeneurin N-terminal domain-containing protein. (181 aa)
LIMS2LIM domain-containing protein. (342 aa)
H3B8U3_LATCHSerine/threonine-protein kinase TOR. (1418 aa)
NPTNNeuroplastin. (346 aa)
CDC42Cell division cycle 42. (156 aa)
WNT2Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (358 aa)
CYFIP1Cytoplasmic FMR1-interacting protein; Belongs to the CYFIP family. (1259 aa)
NEURL1Neuralized E3 ubiquitin protein ligase 1. (568 aa)
NR2E1Nuclear receptor subfamily 2 group E member 1. (477 aa)
H3B780_LATCHUncharacterized protein. (370 aa)
OTPOrthopedia homeobox. (333 aa)
JADE2Jade family PHD finger 2. (790 aa)
H3B6N2_LATCHTeneurin N-terminal domain-containing protein. (214 aa)
PAX6Paired box 6. (463 aa)
PTNPleiotrophin. (167 aa)
CLDN5Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (213 aa)
PLXNB2Plexin B2. (1835 aa)
CTNNB1Catenin beta 1. (781 aa)
BMPR2Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1037 aa)
BAIAP2BAI1 associated protein 2. (434 aa)
H3B4Z7_LATCHUncharacterized protein; Belongs to the cullin family. (1385 aa)
MYOGMyogenin. (242 aa)
METRNMeteorin, glial cell differentiation regulator. (310 aa)
SLC7A5Solute carrier family 7 member 5. (522 aa)
H3B3V9_LATCHMyogenic factor. (221 aa)
MAPTMicrotubule-associated protein. (436 aa)
MYOD1Myogenic factor. (251 aa)
CUX2Homeobox protein cut-like. (1394 aa)
SRFSerum response factor. (520 aa)
DBN1Drebrin 1. (684 aa)
LOC102360711PDGF_2 domain-containing protein; Belongs to the PDGF/VEGF growth factor family. (299 aa)
ANAPC2Anaphase promoting complex subunit 2; Belongs to the cullin family. (816 aa)
H3B181_LATCHTeneurin transmembrane protein 4. (1031 aa)
GFAPGlial fibrillary acidic protein; Belongs to the intermediate filament family. (449 aa)
SNW1SNW domain containing 1. (536 aa)
TESK1Testis associated actin remodelling kinase 1. (600 aa)
C1QTNF9C1q domain-containing protein. (198 aa)
CRKLCRK like proto-oncogene, adaptor protein. (219 aa)
DAB2DAB adaptor protein 2. (745 aa)
FOXG1Forkhead box G1. (409 aa)
ADD1Adducin 1. (805 aa)
ALCAMActivated leukocyte cell adhesion molecule. (530 aa)
FAIMFas apoptotic inhibitory molecule. (179 aa)
PLXND1Plexin D1. (1875 aa)
TIAM1T cell lymphoma invasion and metastasis 1. (1606 aa)
STK11Serine/threonine kinase 11; Belongs to the protein kinase superfamily. (442 aa)
BDNFBrain-derived neurotrophic factor; Promotes the survival of neuronal populations that are all located either in the central nervous system or directly connected to it; Belongs to the NGF-beta family. (254 aa)
FZD3Frizzled class receptor 3; Belongs to the G-protein coupled receptor Fz/Smo family. (604 aa)
MECP2Methyl-CpG binding protein 2. (459 aa)
BRAFB-Raf proto-oncogene, serine/threonine kinase. (768 aa)
CDH5Uncharacterized protein; Cadherins are calcium-dependent cell adhesion proteins. (772 aa)
LRRC45Leucine rich repeat containing 45. (679 aa)
NKX6-1NK6 homeobox 1. (316 aa)
TIAM2T cell lymphoma invasion and metastasis 2. (1727 aa)
MYF6Myogenic factor 6. (272 aa)
LOC102347877Uncharacterized protein. (1033 aa)
CRKCRK proto-oncogene, adaptor protein. (310 aa)
SHTN1Shootin 1. (403 aa)
RND2Rho family GTPase 2. (238 aa)
DCTDopachrome tautomerase. (521 aa)
BADUncharacterized protein. (175 aa)
LOC102357614Fork-head domain-containing protein. (345 aa)
MYOCMyocilin. (272 aa)
LOC102366200Uncharacterized protein; Belongs to the semaphorin family. (627 aa)
ANKRD27Ankyrin repeat domain 27. (888 aa)
ADNPActivity dependent neuroprotector homeobox. (1116 aa)
UFL1UFM1 specific ligase 1. (792 aa)
H3AM01_LATCHIntegrin beta; Belongs to the integrin beta chain family. (769 aa)
RREB1Ras responsive element binding protein 1. (1516 aa)
IL6STInterleukin 6 signal transducer. (922 aa)
LIMS1LIM domain-containing protein. (398 aa)
LOC102350832Zgc:77748. (293 aa)
LOC102358409Uncharacterized protein. (534 aa)
CDKL5Cyclin dependent kinase like 5. (1033 aa)
IL6Uncharacterized protein. (149 aa)
TNFSF11TNF superfamily member 11; Belongs to the tumor necrosis factor family. (169 aa)
H3AHE4_LATCHUncharacterized protein. (463 aa)
RUFY3RUN and FYVE domain containing 3. (715 aa)
GSX2GS homeobox 2. (279 aa)
WNT3Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (331 aa)
KDM1ALysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family. (820 aa)
LOC102363869Si:dkey-28e7.3. (942 aa)
H3AEV1_LATCHTNF_2 domain-containing protein. (230 aa)
GPER1G protein-coupled estrogen receptor 1; Belongs to the G-protein coupled receptor 1 family. (366 aa)
NKX6-2NK6 homeobox 2. (278 aa)
LTALymphotoxin alpha. (166 aa)
CAPRIN2Caprin family member 2. (1014 aa)
PLXNA3Sema domain-containing protein. (698 aa)
XRCC5X-ray repair cross complementing 5. (606 aa)
LOC102360373Fork-head domain-containing protein. (374 aa)
ILKIntegrin linked kinase. (417 aa)
SYNJ1Synaptojanin 1. (1563 aa)
SMAD7Mothers against decapentaplegic homolog. (377 aa)
LYNTyrosine-protein kinase. (515 aa)
PLXNA1Plexin A1. (1387 aa)
ISLRImmunoglobulin superfamily containing leucine rich repeat. (673 aa)
AMIGO3Adhesion molecule with Ig like domain 3. (510 aa)
H3A8K8_LATCHSema domain-containing protein. (2101 aa)
FN1Fibronectin 1. (2295 aa)
MAGMyelin associated glycoprotein. (633 aa)
SERPINE2Serpin family E member 2; Belongs to the serpin family. (403 aa)
IL1RAPL1Interleukin 1 receptor accessory protein like 1. (437 aa)
RETRet proto-oncogene; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1090 aa)
SHANK3SH3 and multiple ankyrin repeat domains 3. (1187 aa)
LOC102366847Uncharacterized protein; Belongs to the semaphorin family. (542 aa)
LOC102356309Uncharacterized protein. (314 aa)
GLI3GLI family zinc finger 3. (1456 aa)
LOC102363099S_100 domain-containing protein; Belongs to the S-100 family. (98 aa)
SEMA4DSemaphorin 4D; Belongs to the semaphorin family. (862 aa)
ITPKAKinase; Belongs to the inositol phosphokinase (IPK) family. (308 aa)
H3A2T1_LATCHUncharacterized protein. (573 aa)
LOC102356030Uncharacterized protein. (313 aa)
H3A2E1_LATCHPlexin_cytopl domain-containing protein. (415 aa)
CAPRIN1Cell cycle associated protein 1. (642 aa)
XRCC2X-ray repair cross complementing 2. (282 aa)
LIG4DNA ligase. (911 aa)
SPENSpen family transcriptional repressor. (3610 aa)
OPRD1Opioid receptor delta 1; Belongs to the G-protein coupled receptor 1 family. (376 aa)
NTRK2Tyrosine-protein kinase receptor. (819 aa)
PLXNB1Plexin B1. (2146 aa)
PLXNA3-2Plexin A3. (1193 aa)
H2ZZI1_LATCHRING-type domain-containing protein. (424 aa)
IST1IST1 factor associated with ESCRT-III. (260 aa)
SMOSmoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family. (820 aa)
SLITRK1SLIT and NTRK like family member 1. (679 aa)
TRIM32Tripartite motif containing 32. (647 aa)
SERPINF1Serpin family F member 1; Belongs to the serpin family. (420 aa)
NEDD9Neural precursor cell expressed, developmentally down-regulated 9. (901 aa)
MYADMMyeloid associated differentiation marker. (314 aa)
EEF2KEukaryotic elongation factor 2 kinase. (512 aa)
PTPRZ1Protein tyrosine phosphatase receptor type Z1. (2273 aa)
TRAK1Trafficking kinesin protein 1. (853 aa)
CHODLChondrolectin. (286 aa)
LOC102364341Uncharacterized protein. (271 aa)
SRRTSerrate, RNA effector molecule. (832 aa)
CLCF1Cardiotrophin like cytokine factor 1. (235 aa)
LOC102347948Uncharacterized protein. (290 aa)
TRIOBPPH domain-containing protein. (597 aa)
ASPAAspartoacylase. (249 aa)
ZFYVE27Uncharacterized protein. (280 aa)
ADIPOQAdiponectin, C1Q and collagen domain containing. (259 aa)
H2ZS97_LATCHTNF_2 domain-containing protein. (143 aa)
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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