(33 nodes) Negative regulation of mitochondrion organization network (Latimeria chalumnae)

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second shell of interactors

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Your Input:
	SLC35F6	Solute carrier family 35 member F6. (374 aa)
	LOC102347917	Uncharacterized protein. (301 aa)
	SLC25A4	Solute carrier family 25 member 4; Belongs to the mitochondrial carrier (TC 2.A.29) family. (298 aa)
	PARL	Presenilin associated, rhomboid-like a. (373 aa)
	OPA1	OPA1 mitochondrial dynamin like GTPase; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (994 aa)
	LOC102354722	Uncharacterized protein. (116 aa)
	GCLC	Glutamate-cysteine ligase catalytic subunit. (655 aa)
	OMA1	OMA1 zinc metallopeptidase. (358 aa)
	LOC102351706	PRELI domain containing 1b. (213 aa)
	BOK	BCL2 family apoptosis regulator BOK. (111 aa)
	VAT1	Vesicle amine transport 1. (414 aa)
	SLC25A6	Solute carrier family 25 member 6; Belongs to the mitochondrial carrier (TC 2.A.29) family. (298 aa)
	FLCN	Folliculin. (576 aa)
	HUWE1	HECT, UBA and WWE domain containing E3 ubiquitin protein ligase 1. (4101 aa)
	SLC25A5	Uncharacterized protein; Belongs to the mitochondrial carrier (TC 2.A.29) family. (298 aa)
	LOC102359041	Zgc:153993. (208 aa)
	PRELID1	PRELI domain containing 1. (216 aa)
	TMEM14A	Transmembrane protein 14A. (101 aa)
	PSMD10	Proteasome 26S subunit, non-ATPase 10. (234 aa)
	BNIP3	BCL2 interacting protein 3. (202 aa)
	TP53	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (401 aa)
	GHITM	Growth hormone inducible transmembrane protein. (354 aa)
	FXN	Frataxin. (194 aa)
	BAK1	BCL2 antagonist/killer 1. (239 aa)
	SLC25A31	Solute carrier family 25 member 31; Belongs to the mitochondrial carrier (TC 2.A.29) family. (321 aa)
	TSPO	Translocator protein. (164 aa)
	RNF41	Ring finger protein 41. (319 aa)
	PINK1	PTEN induced kinase 1. (467 aa)
	TIGAR	TP53 induced glycolysis regulatory phosphatase. (212 aa)
	MUL1	Mitochondrial E3 ubiquitin protein ligase 1. (352 aa)
	IGF1	Insulin like growth factor 1. (136 aa)
	LOC102367579	Translocator protein 2. (163 aa)
	HGF	Hepatocyte growth factor; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Belongs to the peptidase S1 family. Plasminogen subfamily. (720 aa)

Your Current Organism:

Latimeria chalumnae

NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BAK1	LOC102359041	ENSLACP00000018296	ENSLACP00000012675	BCL2 antagonist/killer 1.	Zgc:153993.	0.900
BAK1	TP53	ENSLACP00000018296	ENSLACP00000015915	BCL2 antagonist/killer 1.	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.	0.787
BNIP3	BOK	ENSLACP00000014880	ENSLACP00000009914	BCL2 interacting protein 3.	BCL2 family apoptosis regulator BOK.	0.471
BNIP3	LOC102354722	ENSLACP00000014880	ENSLACP00000003501	BCL2 interacting protein 3.	Uncharacterized protein.	0.901
BNIP3	PINK1	ENSLACP00000014880	ENSLACP00000020138	BCL2 interacting protein 3.	PTEN induced kinase 1.	0.556
BNIP3	TP53	ENSLACP00000014880	ENSLACP00000015915	BCL2 interacting protein 3.	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.	0.412
BOK	BNIP3	ENSLACP00000009914	ENSLACP00000014880	BCL2 family apoptosis regulator BOK.	BCL2 interacting protein 3.	0.471
BOK	LOC102354722	ENSLACP00000009914	ENSLACP00000003501	BCL2 family apoptosis regulator BOK.	Uncharacterized protein.	0.471
FXN	PINK1	ENSLACP00000017270	ENSLACP00000020138	Frataxin.	PTEN induced kinase 1.	0.434
HUWE1	TP53	ENSLACP00000011818	ENSLACP00000015915	HECT, UBA and WWE domain containing E3 ubiquitin protein ligase 1.	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.	0.530
LOC102354722	BNIP3	ENSLACP00000003501	ENSLACP00000014880	Uncharacterized protein.	BCL2 interacting protein 3.	0.901
LOC102354722	BOK	ENSLACP00000003501	ENSLACP00000009914	Uncharacterized protein.	BCL2 family apoptosis regulator BOK.	0.471
LOC102354722	PINK1	ENSLACP00000003501	ENSLACP00000020138	Uncharacterized protein.	PTEN induced kinase 1.	0.452
LOC102354722	TP53	ENSLACP00000003501	ENSLACP00000015915	Uncharacterized protein.	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.	0.412
LOC102359041	BAK1	ENSLACP00000012675	ENSLACP00000018296	Zgc:153993.	BCL2 antagonist/killer 1.	0.900
LOC102359041	TP53	ENSLACP00000012675	ENSLACP00000015915	Zgc:153993.	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.	0.682
LOC102367579	TSPO	ENSLACP00000023211	ENSLACP00000019334	Translocator protein 2.	Translocator protein.	0.908
MUL1	TP53	ENSLACP00000022155	ENSLACP00000015915	Mitochondrial E3 ubiquitin protein ligase 1.	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.	0.537
OMA1	OPA1	ENSLACP00000000842	ENSLACP00000003936	OMA1 zinc metallopeptidase.	OPA1 mitochondrial dynamin like GTPase; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	0.927
OMA1	PARL	ENSLACP00000000842	ENSLACP00000006783	OMA1 zinc metallopeptidase.	Presenilin associated, rhomboid-like a.	0.608