STRINGSTRING
FKBP1A FKBP1A KCNIP3 KCNIP3 WNK4 WNK4 KCNS1 KCNS1 LOC102354291 LOC102354291 KLHL35 KLHL35 ABCC9 ABCC9 DRD3 DRD3 RAMP3 RAMP3 PTPN6 PTPN6 H2ZZF8_LATCH H2ZZF8_LATCH PDGFB PDGFB NEDD4L NEDD4L H3A068_LATCH H3A068_LATCH CASQ1 CASQ1 H3A0M2_LATCH H3A0M2_LATCH LOC102352528 LOC102352528 LRRC55 LRRC55 LOC102352804 LOC102352804 CNTN1 CNTN1 NETO2 NETO2 PTPN3 PTPN3 FFAR1 FFAR1 KCNE4 KCNE4 TMC2 TMC2 ATF4 ATF4 STAC STAC LOC102363383 LOC102363383 VIP VIP CABP5 CABP5 PKD2 PKD2 KCNE3 KCNE3 HECW1 HECW1 WNK3 WNK3 SARAF SARAF CABP4 CABP4 SERPINE2 SERPINE2 SCN1B SCN1B CACNG6 CACNG6 H3A855_LATCH H3A855_LATCH APLNR APLNR ATP1B3 ATP1B3 R3HDM1 R3HDM1 FMR1 FMR1 AMIGO3 AMIGO3 ANO6 ANO6 LYN LYN HTT HTT DHRS7C DHRS7C CHP1 CHP1 PLPP4 PLPP4 BAX BAX PLA2G6 PLA2G6 RANGRF RANGRF CYBA CYBA PIK3CG PIK3CG NETO1 NETO1 INPP5K INPP5K CASQ2 CASQ2 GPER1 GPER1 H3AF01_LATCH H3AF01_LATCH LOC102361922 LOC102361922 WWP2 WWP2 EPB41 EPB41 H3AGN2_LATCH H3AGN2_LATCH FGF11 FGF11 LOC102357829 LOC102357829 H3AHJ4_LATCH H3AHJ4_LATCH LRRC38 LRRC38 CDK5 CDK5 H3AJC3_LATCH H3AJC3_LATCH KCNQ1 KCNQ1 HOMER3 HOMER3 REM1 REM1 RAB44 RAB44 HECW2 HECW2 KCNAB3 KCNAB3 TESC TESC STK39 STK39 H3AM01_LATCH H3AM01_LATCH AKAP6 AKAP6 KCNAB2 KCNAB2 PCSK9 PCSK9 UCN UCN CASK CASK KCNG1 KCNG1 LOC102357515 LOC102357515 CACNG1 CACNG1 CBARP CBARP STIM1 STIM1 STIM2 STIM2 SNTA1 SNTA1 H3ASC2_LATCH H3ASC2_LATCH SCN3B SCN3B LOC102359041 LOC102359041 KCNIP2 KCNIP2 AKAP7 AKAP7 LOC102362971 LOC102362971 TRPC1 TRPC1 H3ATR2_LATCH H3ATR2_LATCH H3ATX3_LATCH H3ATX3_LATCH WFS1 WFS1 JPH2 JPH2 SLC8B1 SLC8B1 DPP10 DPP10 SLC30A1 SLC30A1 SESTD1 SESTD1 SPG11 SPG11 RRAD RRAD CAV1 CAV1 JPH3 JPH3 H3AYA9_LATCH H3AYA9_LATCH CACNB4 CACNB4 HOMER1 HOMER1 NKAIN4 NKAIN4 ATG5 ATG5 ADCYAP1R1 ADCYAP1R1 KCNRG KCNRG KCNS2 KCNS2 STAC2 STAC2 H3B1J8_LATCH H3B1J8_LATCH JPH1 JPH1 IL16 IL16 KCNE2 KCNE2 KCNE1 KCNE1 DRD4 DRD4 NOS1AP NOS1AP SLMAP SLMAP H3B4G8_LATCH H3B4G8_LATCH STC1 STC1 NKX2-5 NKX2-5 LOC102350639 LOC102350639 CACNB1 CACNB1 LOC102359325 LOC102359325 CTNNB1 CTNNB1 NEDD4 NEDD4 CLIC2 CLIC2 CACNB2 CACNB2 H3B845_LATCH H3B845_LATCH BAK1 BAK1 FGF14 FGF14 ABCC8 ABCC8 WNK2 WNK2 RNF207 RNF207 CRACR2A CRACR2A FHL1 FHL1 AMIGO1 AMIGO1 KLHL24 KLHL24 REM2 REM2 PSEN2 PSEN2 CACNB3 CACNB3 NKAIN1 NKAIN1 FGF12 FGF12 NKAIN2 NKAIN2 LOC102354490 LOC102354490 HOMER2 HOMER2 COMMD1 COMMD1 CABP1 CABP1 TGFB1 TGFB1 WNK1 WNK1 CAV3 CAV3 DRD2 DRD2 P2RX1 P2RX1 H3BGE9_LATCH H3BGE9_LATCH ORAI1 ORAI1 SCN4B SCN4B SCN2B SCN2B F2 F2 UBASH3B UBASH3B PACSIN3 PACSIN3 PLCG1 PLCG1 LOC102351798 LOC102351798 LGALS3 LGALS3 R3HDM2 R3HDM2 STAC3 STAC3 LOC102352351 LOC102352351 LOC102362796 LOC102362796 GRIN3B GRIN3B VMP1 VMP1 CHP2 CHP2 P2RX4 P2RX4 EPO EPO TSPAN13 TSPAN13 LOC102359410 LOC102359410 G6PD G6PD FKBP1B FKBP1B TMEM38B TMEM38B THY1 THY1 H2ZUR7_LATCH H2ZUR7_LATCH EFHB EFHB H2ZTT6_LATCH H2ZTT6_LATCH LOC102355203 LOC102355203 LOC102350220 LOC102350220 LOC102351466 LOC102351466 CNTD1 CNTD1 H2ZRT6_LATCH H2ZRT6_LATCH LOC102353789 LOC102353789
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
FKBP1APeptidylprolyl isomerase. (142 aa)
KCNIP3Potassium voltage-gated channel interacting protein 3. (213 aa)
WNK4WNK lysine deficient protein kinase 4. (1163 aa)
KCNS1Potassium voltage-gated channel modifier subfamily S member 1; Belongs to the potassium channel family. (463 aa)
LOC102354291Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (169 aa)
KLHL35Kelch like family member 35. (600 aa)
ABCC9ATP binding cassette subfamily C member 9. (1555 aa)
DRD3Dopamine receptor D3; Belongs to the G-protein coupled receptor 1 family. (443 aa)
RAMP3Receptor activity modifying protein 3. (117 aa)
PTPN6Protein tyrosine phosphatase non-receptor type 6. (338 aa)
H2ZZF8_LATCHRecoverin 3. (164 aa)
PDGFBPDGF_2 domain-containing protein; Belongs to the PDGF/VEGF growth factor family. (209 aa)
NEDD4LE3 ubiquitin-protein ligase. (876 aa)
H3A068_LATCHG_PROTEIN_RECEP_F1_2 domain-containing protein. (326 aa)
CASQ1Calsequestrin; Calsequestrin is a high-capacity, moderate affinity, calcium- binding protein and thus acts as an internal calcium store in muscle. (466 aa)
H3A0M2_LATCHUncharacterized protein. (676 aa)
LOC102352528G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (391 aa)
LRRC55Leucine rich repeat containing 55. (283 aa)
LOC102352804Phosphoinositide phospholipase C. (1172 aa)
CNTN1Contactin 1. (1009 aa)
NETO2Neuropilin and tolloid like 2. (521 aa)
PTPN3Tyrosine-protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class subfamily. (871 aa)
FFAR1Free fatty acid receptor 1. (279 aa)
KCNE4Potassium voltage-gated channel subfamily E regulatory subunit 4. (167 aa)
TMC2Transmembrane channel-like protein. (908 aa)
ATF4Activating transcription factor 4. (374 aa)
STACSH3 and cysteine rich domain. (279 aa)
LOC102363383EF-hand domain-containing protein; Belongs to the S-100 family. (100 aa)
VIPVasoactive intestinal peptide. (205 aa)
CABP5Calcium binding protein 5. (173 aa)
PKD2Polycystin 2, transient receptor potential cation channel. (890 aa)
KCNE3Uncharacterized protein. (92 aa)
HECW1HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1. (1549 aa)
WNK3WNK lysine deficient protein kinase 3. (1769 aa)
SARAFStore-operated calcium entry associated regulatory factor. (349 aa)
CABP4Calcium binding protein 4. (240 aa)
SERPINE2Serpin family E member 2; Belongs to the serpin family. (403 aa)
SCN1BSodium voltage-gated channel beta subunit 1. (221 aa)
CACNG6Voltage-dependent calcium channel gamma-1 subunit; Regulatory subunit of the voltage-gated calcium channel that gives rise to L-type calcium currents in skeletal muscle. Regulates channel inactivation kinetics. (253 aa)
H3A855_LATCHG_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (320 aa)
APLNRApelin receptor; Belongs to the G-protein coupled receptor 1 family. (366 aa)
ATP1B3Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (280 aa)
R3HDM1R3H domain containing 1. (1107 aa)
FMR1Fragile X mental retardation 1. (627 aa)
AMIGO3Adhesion molecule with Ig like domain 3. (510 aa)
ANO6Anoctamin. (766 aa)
LYNTyrosine-protein kinase. (515 aa)
HTTHuntingtin. (3125 aa)
DHRS7CDehydrogenase/reductase 7C; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (311 aa)
CHP1Calcineurin like EF-hand protein 1. (195 aa)
PLPP4Phospholipid phosphatase 4. (269 aa)
BAXUncharacterized protein. (223 aa)
PLA2G6Phospholipase A2 group VI. (815 aa)
RANGRFUncharacterized protein. (203 aa)
CYBACytochrome b-245 alpha chain. (187 aa)
PIK3CGPhosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma; Belongs to the PI3/PI4-kinase family. (1106 aa)
NETO1Neuropilin and tolloid like 1. (385 aa)
INPP5KInositol polyphosphate-5-phosphatase K. (476 aa)
CASQ2Calsequestrin; Calsequestrin is a high-capacity, moderate affinity, calcium- binding protein and thus acts as an internal calcium store in muscle. (412 aa)
GPER1G protein-coupled estrogen receptor 1; Belongs to the G-protein coupled receptor 1 family. (366 aa)
H3AF01_LATCHUncharacterized protein. (658 aa)
LOC102361922Dopamine receptor D2 like; Belongs to the G-protein coupled receptor 1 family. (448 aa)
WWP2E3 ubiquitin-protein ligase. (883 aa)
EPB41Erythrocyte membrane protein band 4.1. (873 aa)
H3AGN2_LATCHUncharacterized protein. (687 aa)
FGF11Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (246 aa)
LOC102357829G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (313 aa)
H3AHJ4_LATCHIon_trans domain-containing protein; Belongs to the potassium channel family. (298 aa)
LRRC38Leucine rich repeat containing 38. (292 aa)
CDK5Cyclin dependent kinase 5. (290 aa)
H3AJC3_LATCHGalectin. (249 aa)
KCNQ1Potassium voltage-gated channel subfamily Q member 1; Belongs to the potassium channel family. (351 aa)
HOMER3Homer scaffold protein 3b. (361 aa)
REM1RRAD and GEM like GTPase 1. (300 aa)
RAB44Uncharacterized protein. (687 aa)
HECW2HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2. (1586 aa)
KCNAB3Potassium voltage-gated channel subfamily A regulatory beta subunit 3. (330 aa)
TESCTescalcin. (218 aa)
STK39Serine/threonine kinase 39. (493 aa)
H3AM01_LATCHIntegrin beta; Belongs to the integrin beta chain family. (769 aa)
AKAP6Uncharacterized protein. (901 aa)
KCNAB2Potassium voltage-gated channel subfamily A regulatory beta subunit 2. (400 aa)
PCSK9Proprotein convertase subtilisin/kexin type 9. (672 aa)
UCNUrocortin. (167 aa)
CASKCalcium/calmodulin dependent serine protein kinase; Belongs to the MAGUK family. (692 aa)
KCNG1Potassium voltage-gated channel modifier subfamily G member 1; Belongs to the potassium channel family. (508 aa)
LOC102357515Uncharacterized protein. (633 aa)
CACNG1Voltage-dependent calcium channel gamma-1 subunit; Regulatory subunit of the voltage-gated calcium channel that gives rise to L-type calcium currents in skeletal muscle. Regulates channel inactivation kinetics. (226 aa)
CBARPCACN subunit beta associated regulatory protein. (667 aa)
STIM1Stromal interaction molecule 1. (662 aa)
STIM2Stromal interaction molecule 2. (639 aa)
SNTA1Syntrophin alpha 1. (481 aa)
H3ASC2_LATCHSolute carrier family 30 member 10. (464 aa)
SCN3BSodium voltage-gated channel beta subunit 3. (216 aa)
LOC102359041Zgc:153993. (208 aa)
KCNIP2Potassium voltage-gated channel interacting protein 2. (98 aa)
AKAP7A-kinase anchoring protein 7. (427 aa)
LOC102362971Si:rp71-17i16.5; Belongs to the PI3/PI4-kinase family. (1081 aa)
TRPC1Transient receptor potential cation channel subfamily C member 1; Belongs to the transient receptor (TC 1.A.4) family. (793 aa)
H3ATR2_LATCHUncharacterized protein. (282 aa)
H3ATX3_LATCHUncharacterized protein. (199 aa)
WFS1Wolframin ER transmembrane glycoprotein. (876 aa)
JPH2Junctophilin; Junctophilins contribute to the formation of junctional membrane complexes (JMCs) which link the plasma membrane with the endoplasmic or sarcoplasmic reticulum in excitable cells. Provides a structural foundation for functional cross-talk between the cell surface and intracellular calcium release channels. (779 aa)
SLC8B1Solute carrier family 8 member B1; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (539 aa)
DPP10Dipeptidyl peptidase like 10; Belongs to the peptidase S9B family. (612 aa)
SLC30A1Solute carrier family 30 member 1. (518 aa)
SESTD1SEC14 and spectrin domain containing 1. (615 aa)
SPG11SPG11 vesicle trafficking associated, spatacsin. (2438 aa)
RRADRRAD, Ras related glycolysis inhibitor and calcium channel regulator. (306 aa)
CAV1Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (148 aa)
JPH3Junctophilin; Junctophilins contribute to the formation of junctional membrane complexes (JMCs) which link the plasma membrane with the endoplasmic or sarcoplasmic reticulum in excitable cells. Provides a structural foundation for functional cross-talk between the cell surface and intracellular calcium release channels. (758 aa)
H3AYA9_LATCHProtein kinase domain-containing protein. (357 aa)
CACNB4Calcium channel, voltage-dependent, beta 4a subunit. (477 aa)
HOMER1Homer scaffold protein 1. (367 aa)
NKAIN4Sodium/potassium transporting ATPase interacting 4. (91 aa)
ATG5Autophagy protein 5; Involved in autophagic vesicle formation. (275 aa)
ADCYAP1R1ADCYAP receptor type I; Belongs to the G-protein coupled receptor 2 family. (337 aa)
KCNRGPotassium channel regulator. (275 aa)
KCNS2Potassium voltage-gated channel modifier subfamily S member 2; Belongs to the potassium channel family. (479 aa)
STAC2SH3 and cysteine rich domain 2. (375 aa)
H3B1J8_LATCHAKAP7_NLS domain-containing protein. (240 aa)
JPH1Junctophilin; Junctophilins contribute to the formation of junctional membrane complexes (JMCs) which link the plasma membrane with the endoplasmic or sarcoplasmic reticulum in excitable cells. Provides a structural foundation for functional cross-talk between the cell surface and intracellular calcium release channels. (639 aa)
IL16Pro-interleukin-16; Interleukin-16 stimulates a migratory response in CD4+ lymphocytes, monocytes, and eosinophils. Primes CD4+ T-cells for IL-2 and IL-15 responsiveness. Also induces T-lymphocyte expression of interleukin 2 receptor. Ligand for CD4. (1208 aa)
KCNE2Potassium voltage-gated channel subfamily E regulatory subunit 2. (125 aa)
KCNE1Uncharacterized protein. (122 aa)
DRD4Dopamine receptor D4; Belongs to the G-protein coupled receptor 1 family. (382 aa)
NOS1APUncharacterized protein. (192 aa)
SLMAPSarcolemma associated protein. (782 aa)
H3B4G8_LATCHUncharacterized protein; Belongs to the peptidase S9B family. (801 aa)
STC1Stanniocalcin 1. (250 aa)
NKX2-5NK2 homeobox 5. (296 aa)
LOC102350639G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (374 aa)
CACNB1Calcium voltage-gated channel auxiliary subunit beta 1. (625 aa)
LOC102359325Calcium binding protein 2a. (225 aa)
CTNNB1Catenin beta 1. (781 aa)
NEDD4NEDD4 E3 ubiquitin protein ligase. (1313 aa)
CLIC2Chloride intracellular channel protein; Belongs to the chloride channel CLIC family. (251 aa)
CACNB2Calcium voltage-gated channel auxiliary subunit beta 2. (548 aa)
H3B845_LATCHG_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (299 aa)
BAK1BCL2 antagonist/killer 1. (239 aa)
FGF14Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (163 aa)
ABCC8ATP binding cassette subfamily C member 8. (1591 aa)
WNK2WNK lysine deficient protein kinase 2. (1994 aa)
RNF207Ring finger protein 207. (648 aa)
CRACR2AUncharacterized protein. (316 aa)
FHL1Four and a half LIM domains 1. (232 aa)
AMIGO1Adhesion molecule with Ig like domain 1. (506 aa)
KLHL24Kelch like family member 24. (596 aa)
REM2RRAD and GEM like GTPase 2. (295 aa)
PSEN2Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (458 aa)
CACNB3Calcium voltage-gated channel auxiliary subunit beta 3. (486 aa)
NKAIN1Sodium/potassium transporting ATPase interacting 1. (208 aa)
FGF12Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (243 aa)
NKAIN2Sodium/potassium transporting ATPase interacting 2. (79 aa)
LOC102354490Apelin receptor a; Belongs to the G-protein coupled receptor 1 family. (356 aa)
HOMER2Homer scaffold protein 2. (354 aa)
COMMD1Copper metabolism domain containing 1. (188 aa)
CABP1Calcium binding protein 1. (217 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (401 aa)
WNK1WNK lysine deficient protein kinase 1. (2654 aa)
CAV3Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (153 aa)
DRD2G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (450 aa)
P2RX1P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (403 aa)
H3BGE9_LATCHUncharacterized protein. (273 aa)
ORAI1ORAI calcium release-activated calcium modulator 1. (256 aa)
SCN4BSodium voltage-gated channel beta subunit 4. (210 aa)
SCN2BSodium voltage-gated channel beta subunit 2. (215 aa)
F2Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family. (618 aa)
UBASH3BUbiquitin associated and SH3 domain containing B. (607 aa)
PACSIN3Protein kinase C and casein kinase substrate in neurons 3. (486 aa)
PLCG11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1219 aa)
LOC102351798Galectin. (167 aa)
LGALS3Galectin. (274 aa)
R3HDM2R3H domain containing 2. (971 aa)
STAC3SH3 and cysteine rich domain 3. (373 aa)
LOC102352351C-C motif chemokine. (88 aa)
LOC102362796Uncharacterized protein. (451 aa)
GRIN3BGlutamate ionotropic receptor NMDA type subunit 3B. (907 aa)
VMP1Vacuole membrane protein 1. (406 aa)
CHP2Calcineurin like EF-hand protein 2. (194 aa)
P2RX4P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (391 aa)
EPOErythropoietin. (179 aa)
TSPAN13Tetraspanin 13; Belongs to the tetraspanin (TM4SF) family. (203 aa)
LOC102359410G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (387 aa)
G6PDGlucose-6-phosphate 1-dehydrogenase; Catalyzes the rate-limiting step of the oxidative pentose- phosphate pathway, which represents a route for the dissimilation of carbohydrates besides glycolysis. (430 aa)
FKBP1BPeptidylprolyl isomerase. (79 aa)
TMEM38BTransmembrane protein 38B. (302 aa)
THY1Thy-1 cell surface antigen. (165 aa)
H2ZUR7_LATCHUncharacterized protein. (73 aa)
EFHBEF-hand domain family member B. (578 aa)
H2ZTT6_LATCHPhosphoinositide phospholipase C. (404 aa)
LOC102355203Na_H_Exchanger domain-containing protein. (161 aa)
LOC102350220Dipeptidyl-peptidase 6b; Belongs to the peptidase S9B family. (418 aa)
LOC102351466Uncharacterized protein. (201 aa)
CNTD1Cyclin N-terminal domain containing 1. (274 aa)
H2ZRT6_LATCHUncharacterized protein. (78 aa)
LOC102353789G_PROTEIN_RECEP_F1_2 domain-containing protein. (344 aa)
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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