STRINGSTRING
CDC26 CDC26 GEN1 GEN1 CDC27 CDC27 TPR TPR ANAPC7 ANAPC7 ZNF207 ZNF207 CDC23 CDC23 CUL3 CUL3 SPDL1 SPDL1 KNTC1 KNTC1 BCL7A BCL7A ANAPC5 ANAPC5 RIOK2 RIOK2 CDC16 CDC16 CDT1 CDT1 BUB3 BUB3 TEX14 TEX14 H3A0V9_LATCH H3A0V9_LATCH PCID2 PCID2 PLK1 PLK1 MAD2L1BP MAD2L1BP PSMG2 PSMG2 RB1 RB1 ATM ATM ANAPC11 ANAPC11 ZWILCH ZWILCH MAD2L1 MAD2L1 ZW10 ZW10 BCL7C BCL7C XRCC3 XRCC3 FBXO5 FBXO5 PTTG1 PTTG1 H3ASX0_LATCH H3ASX0_LATCH H3ATF5_LATCH H3ATF5_LATCH ANAPC1 ANAPC1 MAD1L1 MAD1L1 DYNC1LI1 DYNC1LI1 TTK TTK BUB1 BUB1 UBE2C UBE2C LCMT1 LCMT1 H3AZY7_LATCH H3AZY7_LATCH ANAPC2 ANAPC2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CDC26Cell division cycle 26. (85 aa)
GEN1GEN1 Holliday junction 5' flap endonuclease. (899 aa)
CDC27Cell division cycle 27. (833 aa)
TPRTranslocated promoter region, nuclear basket protein. (2360 aa)
ANAPC7Anaphase promoting complex subunit 7. (565 aa)
ZNF207Zinc finger protein 207. (482 aa)
CDC23Cell division cycle 23. (581 aa)
CUL3Cullin 3; Belongs to the cullin family. (769 aa)
SPDL1Protein Spindly; Required for the localization of dynein and dynactin to the mitotic kintochore. Dynein is believed to control the initial lateral interaction between the kinetochore and spindle microtubules and to facilitate the subsequent formation of end-on kinetochore-microtubule attachments mediated by the NDC80 complex; Belongs to the Spindly family. (614 aa)
KNTC1Kinetochore associated 1. (2225 aa)
BCL7ABAF chromatin remodeling complex subunit BCL7A. (236 aa)
ANAPC5Anaphase promoting complex subunit 5. (755 aa)
RIOK2RIO kinase 2. (542 aa)
CDC16Cell division cycle 16. (545 aa)
CDT1Chromatin licensing and DNA replication factor 1. (520 aa)
BUB3BUB3 mitotic checkpoint protein. (361 aa)
TEX14Protein kinase domain-containing protein. (937 aa)
H3A0V9_LATCHDUF5595 domain-containing protein. (661 aa)
PCID2PCI domain containing 2. (452 aa)
PLK1Serine/threonine-protein kinase PLK. (595 aa)
MAD2L1BPMAD2L1 binding protein. (419 aa)
PSMG2Proteasome assembly chaperone 2. (205 aa)
RB1Uncharacterized protein. (411 aa)
ATMATM serine/threonine kinase. (2375 aa)
ANAPC11APC11 anaphase promoting complex subunit 11 homolog (yeast). (84 aa)
ZWILCHZwilch kinetochore protein. (512 aa)
MAD2L1Mitotic arrest deficient 2 like 1. (202 aa)
ZW10Zw10 kinetochore protein. (708 aa)
BCL7CUncharacterized protein. (219 aa)
XRCC3DNA repair protein; Involved in the homologous recombination repair (HRR) pathway of double-stranded DNA, thought to repair chromosomal fragmentation, translocations and deletions; Belongs to the RecA family. RAD51 subfamily. (358 aa)
FBXO5F-box protein 5. (313 aa)
PTTG1Uncharacterized protein. (171 aa)
H3ASX0_LATCHKinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (397 aa)
H3ATF5_LATCHCdc6_C domain-containing protein. (525 aa)
ANAPC1Anaphase promoting complex subunit 1. (1891 aa)
MAD1L1Mitotic arrest deficient 1 like 1. (684 aa)
DYNC1LI1Dynein light intermediate chain; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes. (502 aa)
TTKTTK protein kinase. (889 aa)
BUB1BUB1 mitotic checkpoint serine/threonine kinase. (1272 aa)
UBE2CUbiquitin conjugating enzyme E2 C; Belongs to the ubiquitin-conjugating enzyme family. (179 aa)
LCMT1Leucine carboxyl methyltransferase 1; Methylates the carboxyl group of the C-terminal leucine residue of protein phosphatase 2A catalytic subunits to form alpha- leucine ester residues; Belongs to the methyltransferase superfamily. LCMT family. (325 aa)
H3AZY7_LATCHKelch-like family member 22. (628 aa)
ANAPC2Anaphase promoting complex subunit 2; Belongs to the cullin family. (816 aa)
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.