STRINGSTRING
TSC2 TSC2 LRRC1 LRRC1 BBS4 BBS4 TRAF6 TRAF6 LOC102354865 LOC102354865 OPA1 OPA1 LMO4 LMO4 PTCH1 PTCH1 ABL2 ABL2 MTHFD1L MTHFD1L KDM6A KDM6A LIAS LIAS SEC24B SEC24B SFRP2 SFRP2 LOC102362951 LOC102362951 CECR2 CECR2 SETD2 SETD2 CLUAP1 CLUAP1 LOC102353169 LOC102353169 HECTD1 HECTD1 SHROOM3 SHROOM3 H3AJF8_LATCH H3AJF8_LATCH MTHFR MTHFR SUFU SUFU H3ALU1_LATCH H3ALU1_LATCH ARHGAP35 ARHGAP35 STIL STIL FZD3 FZD3 TSC1 TSC1 VASP VASP IFT57 IFT57 PRKACB PRKACB APAF1 APAF1 PTK7 PTK7 SALL4 SALL4 CTHRC1 CTHRC1 GLMN GLMN DEAF1 DEAF1 DVL3 DVL3 DVL2 DVL2 H3B780_LATCH H3B780_LATCH ABL1 ABL1 MTHFD1 MTHFD1 TMED2 TMED2 PHACTR4 PHACTR4 BMP7 BMP7 TGFB1 TGFB1 ST14 ST14 DVL1 DVL1 MKS1 MKS1 FUZ FUZ M3XL62_LATCH M3XL62_LATCH
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
TSC2TSC complex subunit 2. (1836 aa)
LRRC1Uncharacterized protein. (155 aa)
BBS4Bardet-Biedl syndrome 4. (537 aa)
TRAF6TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (559 aa)
LOC102354865Uncharacterized protein. (746 aa)
OPA1OPA1 mitochondrial dynamin like GTPase; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (994 aa)
LMO4LIM domain only 4b. (165 aa)
PTCH1Patched 1. (1287 aa)
ABL2Tyrosine-protein kinase. (1175 aa)
MTHFD1LUncharacterized protein. (90 aa)
KDM6ALysine (K)-specific demethylase 6A. (1452 aa)
LIASLipoyl synthase, mitochondrial; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. (387 aa)
SEC24BSEC24 homolog B, COPII coat complex component. (1197 aa)
SFRP2Secreted frizzled related protein 2. (294 aa)
LOC102362951Protein kinase, cAMP-dependent, catalytic, alpha, genome duplicate a; Belongs to the protein kinase superfamily. (351 aa)
CECR2CECR2 histone acetyl-lysine reader. (1363 aa)
SETD2SET domain containing 2, histone lysine methyltransferase. (2541 aa)
CLUAP1Clusterin associated protein 1. (348 aa)
LOC102353169Uncharacterized protein. (245 aa)
HECTD1HECT domain E3 ubiquitin protein ligase 1. (2580 aa)
SHROOM3Shroom family member 3. (1790 aa)
H3AJF8_LATCHPeptidase S1 domain-containing protein. (483 aa)
MTHFRMethylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. (650 aa)
SUFUSUFU negative regulator of hedgehog signaling. (422 aa)
H3ALU1_LATCHUncharacterized protein. (1358 aa)
ARHGAP35Rho GTPase activating protein 35b. (1487 aa)
STILSTIL centriolar assembly protein. (1298 aa)
FZD3Frizzled class receptor 3; Belongs to the G-protein coupled receptor Fz/Smo family. (604 aa)
TSC1TSC complex subunit 1. (1217 aa)
VASPVasodilator stimulated phosphoprotein. (444 aa)
IFT57Intraflagellar transport 57. (428 aa)
PRKACBUncharacterized protein; Belongs to the protein kinase superfamily. (351 aa)
APAF1Apoptotic peptidase activating factor 1. (1202 aa)
PTK7Protein tyrosine kinase 7 (inactive); Belongs to the protein kinase superfamily. Tyr protein kinase family. (1067 aa)
SALL4Spalt like transcription factor 4. (1002 aa)
CTHRC1Collagen triple helix repeat containing 1. (151 aa)
GLMNGlomulin, FKBP associated protein. (597 aa)
DEAF1DEAF1 transcription factor. (565 aa)
DVL3Dishevelled segment polarity protein 3. (716 aa)
DVL2Dishevelled segment polarity protein 2. (401 aa)
H3B780_LATCHUncharacterized protein. (370 aa)
ABL1Tyrosine-protein kinase. (1156 aa)
MTHFD1Methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1. (930 aa)
TMED2Transmembrane p24 trafficking protein 2. (208 aa)
PHACTR4Phosphatase and actin regulator. (702 aa)
BMP7Bone morphogenetic protein 7. (425 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (401 aa)
ST14Suppressor of tumorigenicity 14 protein homolog; Degrades extracellular matrix. (845 aa)
DVL1Dishevelled segment polarity protein 1. (552 aa)
MKS1MKS transition zone complex subunit 1. (561 aa)
FUZFuzzy planar cell polarity protein. (426 aa)
M3XL62_LATCHUncharacterized protein. (269 aa)
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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