STRINGSTRING
H2ZTZ4_LATCH H2ZTZ4_LATCH NTRK2 NTRK2 ARHGEF10 ARHGEF10 SH3TC2 SH3TC2 H3A9H6_LATCH H3A9H6_LATCH LOC102362617 LOC102362617 ILK ILK H3AFZ1_LATCH H3AFZ1_LATCH CDK5 CDK5 LOC102367411 LOC102367411 MYOC MYOC MPP5 MPP5 NDRG1 NDRG1 SH3TC1 SH3TC1 ITGB4 ITGB4 DAG1 DAG1 ADAM22 ADAM22 LAMB2 LAMB2 PARD3 PARD3 NF1 NF1 PRX PRX
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
Your Input:
H2ZTZ4_LATCHFatty acid 2-hydroxylase; Catalyzes stereospecific hydroxylation of free fatty acids at the C-2 position to produce (R)-2-hydroxy fatty acids, which are building blocks of sphingolipids and glycosphingolipids common in neural tissue and epidermis. Plays an essential role in the synthesis of galactosphingolipids of the myelin sheath. Responsible for the synthesis of sphingolipids and glycosphingolipids involved in the formation of epidermal lamellar bodies critical for skin permeability barrier. Participates in the synthesis of glycosphingolipids and a fraction of type II wax diesters i [...] (363 aa)
NTRK2Tyrosine-protein kinase receptor. (819 aa)
ARHGEF10Rho guanine nucleotide exchange factor 10. (1338 aa)
SH3TC2SH3 domain and tetratricopeptide repeats 2. (1203 aa)
H3A9H6_LATCHFatty acid hydroxylase domain-containing protein; Belongs to the sterol desaturase family. (264 aa)
LOC102362617Fatty acid 2-hydroxylase; Catalyzes stereospecific hydroxylation of free fatty acids at the C-2 position to produce (R)-2-hydroxy fatty acids, which are building blocks of sphingolipids and glycosphingolipids common in neural tissue and epidermis. Plays an essential role in the synthesis of galactosphingolipids of the myelin sheath. Responsible for the synthesis of sphingolipids and glycosphingolipids involved in the formation of epidermal lamellar bodies critical for skin permeability barrier. Participates in the synthesis of glycosphingolipids and a fraction of type II wax diesters i [...] (370 aa)
ILKIntegrin linked kinase. (417 aa)
H3AFZ1_LATCHPeptidase S72 domain-containing protein. (633 aa)
CDK5Cyclin dependent kinase 5. (290 aa)
LOC102367411Cytochrome b5 heme-binding domain-containing protein; Belongs to the cytochrome b5 family. (334 aa)
MYOCMyocilin. (272 aa)
MPP5Membrane palmitoylated protein 5; Belongs to the MAGUK family. (678 aa)
NDRG1N-myc downstream regulated 1. (402 aa)
SH3TC1SH3 domain and tetratricopeptide repeats 1. (1263 aa)
ITGB4Integrin beta. (1787 aa)
DAG1Dystroglycan 1. (900 aa)
ADAM22ADAM metallopeptidase domain 22. (728 aa)
LAMB2Laminin subunit beta 2. (1781 aa)
PARD3Par-3 family cell polarity regulator. (1214 aa)
NF1Neurofibromin 1. (2814 aa)
PRXPeriaxin. (1446 aa)
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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