STRINGSTRING
ZFPM2 ZFPM2 IFT20 IFT20 BMP7 BMP7 PRMT1 PRMT1 LOC102352268 LOC102352268 MTOR MTOR H3B976_LATCH H3B976_LATCH H3B938_LATCH H3B938_LATCH H3B8U3_LATCH H3B8U3_LATCH CSRP3 CSRP3 WNT2 WNT2 LOC102366172 LOC102366172 TAZ TAZ LOC102365660 LOC102365660 H3B6N2_LATCH H3B6N2_LATCH TBX2 TBX2 NKX2-5 NKX2-5 AKAP13 AKAP13 LOC102350553 LOC102350553 SRF SRF BMP2 BMP2 PTCD2 PTCD2 MYOCD MYOCD H3B181_LATCH H3B181_LATCH MYL7 MYL7 ATG5 ATG5 SAV1 SAV1 MEF2C MEF2C DLL4 DLL4 GJC1 GJC1 IRX3 IRX3 VWA5B2 VWA5B2 ANKRD1 ANKRD1 MED1 MED1 SGCD SGCD TSC1 TSC1 SMAD1 SMAD1 MAML1 MAML1 TNNI1 TNNI1 TBX20 TBX20 PGM5 PGM5 NOX4 NOX4 LOC102353564 LOC102353564 H3APB2_LATCH H3APB2_LATCH ACVR1 ACVR1 H3AM65_LATCH H3AM65_LATCH PDLIM5 PDLIM5 ACADM ACADM SEMA3C SEMA3C SMAD4 SMAD4 LRRC10B LRRC10B SGCZ SGCZ CBY1 CBY1 LOC102351081 LOC102351081 SIRT6 SIRT6 JARID2 JARID2 TGFBR1 TGFBR1 KDM6B KDM6B NPRL3 NPRL3 LOC102347576 LOC102347576 TGFB2 TGFB2 IFRD1 IFRD1 ZMPSTE24 ZMPSTE24 TBX3 TBX3 GREM1 GREM1 SMAD7 SMAD7 EDNRA EDNRA LRRC10 LRRC10 ARID2 ARID2 CXADR CXADR DIPK2A DIPK2A ASB2 ASB2 NRAP NRAP GATA6 GATA6 TNNI3 TNNI3 EYA2 EYA2 GJA5 GJA5 ADRA1A ADRA1A MEF2A MEF2A LOC102355203 LOC102355203 PKP2 PKP2 MAP2K4 MAP2K4 ENG ENG LOC102358988 LOC102358988 BMP4 BMP4 HAND1 HAND1 TNNC1 TNNC1 ZFPM1 ZFPM1 H3BFZ2_LATCH H3BFZ2_LATCH H3BFW7_LATCH H3BFW7_LATCH TGFB1 TGFB1 WNT2B WNT2B
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ZFPM2Zinc finger protein, FOG family member 2. (979 aa)
IFT20Intraflagellar transport 20. (132 aa)
BMP7Bone morphogenetic protein 7. (425 aa)
PRMT1Protein arginine methyltransferase 1; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (320 aa)
LOC102352268Transforming growth factor beta; Belongs to the TGF-beta family. (414 aa)
MTORMechanistic target of rapamycin kinase; Belongs to the PI3/PI4-kinase family. (1009 aa)
H3B976_LATCHUncharacterized protein. (1585 aa)
H3B938_LATCHTeneurin N-terminal domain-containing protein. (181 aa)
H3B8U3_LATCHSerine/threonine-protein kinase TOR. (1418 aa)
CSRP3Cysteine and glycine rich protein 3. (192 aa)
WNT2Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (358 aa)
LOC102366172Uncharacterized protein. (183 aa)
TAZTafazzin family protein; Belongs to the taffazin family. (264 aa)
LOC102365660Uncharacterized protein. (187 aa)
H3B6N2_LATCHTeneurin N-terminal domain-containing protein. (214 aa)
TBX2T-box transcription factor 2. (689 aa)
NKX2-5NK2 homeobox 5. (296 aa)
AKAP13PH domain-containing protein. (644 aa)
LOC102350553Uncharacterized protein. (232 aa)
SRFSerum response factor. (520 aa)
BMP2Bone morphogenetic protein 2. (402 aa)
PTCD2Pentatricopeptide repeat domain 2. (405 aa)
MYOCDMyocardin. (963 aa)
H3B181_LATCHTeneurin transmembrane protein 4. (1031 aa)
MYL7Myosin light chain 7. (182 aa)
ATG5Autophagy protein 5; Involved in autophagic vesicle formation. (275 aa)
SAV1Salvador family WW domain containing protein 1. (393 aa)
MEF2CMyocyte enhancer factor 2C. (462 aa)
DLL4Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (688 aa)
GJC1Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. (390 aa)
IRX3Iroquois homeobox 3. (447 aa)
VWA5B2Von Willebrand factor A domain containing 5B2. (1246 aa)
ANKRD1Ankyrin repeat domain 1. (319 aa)
MED1Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1401 aa)
SGCDUncharacterized protein. (62 aa)
TSC1TSC complex subunit 1. (1217 aa)
SMAD1Mothers against decapentaplegic homolog. (465 aa)
MAML1Mastermind like transcriptional coactivator 1. (1039 aa)
TNNI1Troponin I1, slow skeletal type. (171 aa)
TBX20T-box transcription factor 20. (441 aa)
PGM5Phosphoglucomutase 5; Belongs to the phosphohexose mutase family. (567 aa)
NOX4NADPH oxidase 4. (541 aa)
LOC102353564Uncharacterized protein. (161 aa)
H3APB2_LATCHFork-head domain-containing protein. (408 aa)
ACVR1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (506 aa)
H3AM65_LATCHMediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (472 aa)
PDLIM5PDZ and LIM domain 5. (629 aa)
ACADMAcyl-CoA dehydrogenase medium chain. (424 aa)
SEMA3CSemaphorin 3C; Belongs to the semaphorin family. (550 aa)
SMAD4MH2 domain-containing protein. (412 aa)
LRRC10BLeucine rich repeat containing 10B. (278 aa)
SGCZSarcoglycan zeta. (106 aa)
CBY1Uncharacterized protein. (127 aa)
LOC102351081Bone morphogenetic protein 16. (396 aa)
SIRT6Sirtuin 6. (375 aa)
JARID2Jumonji and AT-rich interaction domain containing 2. (906 aa)
TGFBR1Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (507 aa)
KDM6BLysine demethylase 6B. (1638 aa)
NPRL3NPR3 like, GATOR1 complex subunit. (396 aa)
LOC102347576SH3 domain-containing protein. (2968 aa)
TGFB2Transforming growth factor beta; Belongs to the TGF-beta family. (415 aa)
IFRD1Interferon related developmental regulator 1. (446 aa)
ZMPSTE24CAAX prenyl protease; Proteolytically removes the C-terminal three residues of farnesylated proteins; Belongs to the peptidase M48A family. (453 aa)
TBX3T-box transcription factor 3. (713 aa)
GREM1Gremlin 1, DAN family BMP antagonist. (189 aa)
SMAD7Mothers against decapentaplegic homolog. (377 aa)
EDNRAEndothelin receptor type A; Belongs to the G-protein coupled receptor 1 family. (424 aa)
LRRC10Uncharacterized protein. (244 aa)
ARID2AT-rich interaction domain 2. (1771 aa)
CXADRCXADR Ig-like cell adhesion molecule. (297 aa)
DIPK2ADivergent protein kinase domain 2A. (434 aa)
ASB2Ankyrin repeat and SOCS box containing 2. (658 aa)
NRAPNebulin related anchoring protein. (1783 aa)
GATA6GATA binding protein 6. (503 aa)
TNNI3Uncharacterized protein. (240 aa)
EYA2Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family. (579 aa)
GJA5Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. (371 aa)
ADRA1AAdrenoceptor alpha 1A. (459 aa)
MEF2AMyocyte enhancer factor 2A. (468 aa)
LOC102355203Na_H_Exchanger domain-containing protein. (161 aa)
PKP2Uncharacterized protein. (815 aa)
MAP2K4Mitogen-activated protein kinase kinase 4; Belongs to the protein kinase superfamily. (463 aa)
ENGEndoglin. (674 aa)
LOC102358988Mothers against decapentaplegic homolog. (614 aa)
BMP4Bone morphogenetic protein 4. (460 aa)
HAND1Heart and neural crest derivatives expressed 1. (196 aa)
TNNC1Troponin C type 1a (slow). (164 aa)
ZFPM1Zinc finger protein, FOG family member 1. (1017 aa)
H3BFZ2_LATCHBHLH domain-containing protein. (165 aa)
H3BFW7_LATCHBHLH domain-containing protein. (161 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (401 aa)
WNT2BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (370 aa)
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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