STRINGSTRING
GSK3A GSK3A LOC102347966 LOC102347966 GSK3B GSK3B ATP2B4 ATP2B4 ROCK1 ROCK1 LOC102360622 LOC102360622 TRIM63 TRIM63 EDN1 EDN1 LMCD1 LMCD1 LOC102358988 LOC102358988 P2RX4 P2RX4 G6PD G6PD TNFRSF1B TNFRSF1B AKAP6 AKAP6 LOC102356355 LOC102356355 IL6ST IL6ST SMAD4 SMAD4 H3AF01_LATCH H3AF01_LATCH IGFBP5 IGFBP5 PDE9A PDE9A ERRFI1 ERRFI1 TOMM70 TOMM70 GLRX3 GLRX3 MLIP MLIP HAND2 HAND2 H3A551_LATCH H3A551_LATCH PARP2 PARP2 PARP1 PARP1 CTDP1 CTDP1 ADRA1A ADRA1A LOC102355203 LOC102355203
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
GSK3AGlycogen synthase kinase 3 alpha a; Belongs to the protein kinase superfamily. (463 aa)
LOC102347966SCP domain-containing protein; Belongs to the CRISP family. (163 aa)
GSK3BGlycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily. (420 aa)
ATP2B4Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1233 aa)
ROCK1Rho associated coiled-coil containing protein kinase 1; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (1350 aa)
LOC102360622Phosphodiesterase. (504 aa)
TRIM63Tripartite motif containing 63. (354 aa)
EDN1Endothelin 1. (216 aa)
LMCD1LIM and cysteine rich domains 1. (375 aa)
LOC102358988Mothers against decapentaplegic homolog. (614 aa)
P2RX4P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (391 aa)
G6PDGlucose-6-phosphate 1-dehydrogenase; Catalyzes the rate-limiting step of the oxidative pentose- phosphate pathway, which represents a route for the dissimilation of carbohydrates besides glycolysis. (430 aa)
TNFRSF1BTNF receptor superfamily member 1B. (465 aa)
AKAP6Uncharacterized protein. (901 aa)
LOC102356355TNFR-Cys domain-containing protein. (163 aa)
IL6STInterleukin 6 signal transducer. (922 aa)
SMAD4MH2 domain-containing protein. (412 aa)
H3AF01_LATCHUncharacterized protein. (658 aa)
IGFBP5Insulin like growth factor binding protein 5. (279 aa)
PDE9APhosphodiesterase. (519 aa)
ERRFI1ERBB receptor feedback inhibitor 1. (468 aa)
TOMM70Translocase of outer mitochondrial membrane 70. (601 aa)
GLRX3Glutaredoxin 3. (332 aa)
MLIPUncharacterized protein. (1070 aa)
HAND2Heart and neural crest derivatives expressed 2. (210 aa)
H3A551_LATCHPhosphodiesterase. (437 aa)
PARP2Poly [ADP-ribose] polymerase. (502 aa)
PARP1Poly [ADP-ribose] polymerase; Poly-ADP-ribosyltransferase that mediates poly-ADP- ribosylation of proteins and plays a key role in DNA repair. (1011 aa)
CTDP1RNA polymerase II subunit A C-terminal domain phosphatase; This promotes the activity of RNA polymerase II. (846 aa)
ADRA1AAdrenoceptor alpha 1A. (459 aa)
LOC102355203Na_H_Exchanger domain-containing protein. (161 aa)
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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